5R97
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![BU of 5r97 by Molmil](/molmil-images/mine/5r97) | PanDDA analysis group deposition Form1 MAP kinase p38-alpha -- Fragment N13662a in complex with MAP kinase p38-alpha | Descriptor: | 4-(piperidin-1-yl)-1,2,5-oxadiazol-3-amine, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | De Nicola, G.F, Nichols, C.E. | Deposit date: | 2020-03-04 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.438 Å) | Cite: | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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5R9L
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![BU of 5r9l by Molmil](/molmil-images/mine/5r9l) | |
5RA3
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![BU of 5ra3 by Molmil](/molmil-images/mine/5ra3) | |
5R8E
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![BU of 5r8e by Molmil](/molmil-images/mine/5r8e) | PanDDA analysis group deposition INTERLEUKIN-1 BETA -- Fragment Z57475877 in complex with INTERLEUKIN-1 BETA | Descriptor: | Interleukin-1 beta, SULFATE ION, ~{N}-(2-ethyl-1,2,3,4-tetrazol-5-yl)butanamide | Authors: | De Nicola, G.F, Nichols, C.E. | Deposit date: | 2020-03-03 | Release date: | 2020-04-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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5R8Q
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![BU of 5r8q by Molmil](/molmil-images/mine/5r8q) | |
5R98
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![BU of 5r98 by Molmil](/molmil-images/mine/5r98) | |
5R9N
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![BU of 5r9n by Molmil](/molmil-images/mine/5r9n) | |
5R9Z
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![BU of 5r9z by Molmil](/molmil-images/mine/5r9z) | |
5R85
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![BU of 5r85 by Molmil](/molmil-images/mine/5r85) | |
5R8G
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![BU of 5r8g by Molmil](/molmil-images/mine/5r8g) | |
5R8X
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![BU of 5r8x by Molmil](/molmil-images/mine/5r8x) | |
5R9D
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![BU of 5r9d by Molmil](/molmil-images/mine/5r9d) | |
5R9T
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![BU of 5r9t by Molmil](/molmil-images/mine/5r9t) | PanDDA analysis group deposition Form1 MAP kinase p38-alpha -- Fragment N13477a in complex with MAP kinase p38-alpha | Descriptor: | 6-methyl-5-[(4-propan-2-ylphenyl)amino]-2~{H}-1,2,4-triazin-3-one, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | De Nicola, G.F, Nichols, C.E. | Deposit date: | 2020-03-04 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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5RA9
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![BU of 5ra9 by Molmil](/molmil-images/mine/5ra9) | |
5R8C
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![BU of 5r8c by Molmil](/molmil-images/mine/5r8c) | |
5R8U
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![BU of 5r8u by Molmil](/molmil-images/mine/5r8u) | |
5R9B
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![BU of 5r9b by Molmil](/molmil-images/mine/5r9b) | |
5R9S
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![BU of 5r9s by Molmil](/molmil-images/mine/5r9s) | |
5R8D
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![BU of 5r8d by Molmil](/molmil-images/mine/5r8d) | |
5R8V
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![BU of 5r8v by Molmil](/molmil-images/mine/5r8v) | |
5R9A
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![BU of 5r9a by Molmil](/molmil-images/mine/5r9a) | |
5R9Q
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![BU of 5r9q by Molmil](/molmil-images/mine/5r9q) | |
5R8I
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![BU of 5r8i by Molmil](/molmil-images/mine/5r8i) | |
5RA5
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![BU of 5ra5 by Molmil](/molmil-images/mine/5ra5) | |
5R91
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![BU of 5r91 by Molmil](/molmil-images/mine/5r91) | |