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Structure of EGFR_D770_N771insNPG/V948R in complex with covalent inhibitor Osimertinib.
Descriptor:	1,2-ETHANEDIOL, CITRIC ACID, Epidermal growth factor receptor, ...
Authors:	Skene, R.J, Lane, W.
Deposit date:	2021-01-21
Release date:	2021-09-22
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non-Small Cell Lung Cancer. Cancer Discov, 11, 2021

Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
Descriptor:	COPPER (I) ION, Plastocyanin
Authors:	Crowley, P.B, Matias, P.M, Mi, H, Firbank, S.J, Banfield, M.J, Dennison, C.
Deposit date:	2008-04-18
Release date:	2008-07-08
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Regulation of protein function: crystal packing interfaces and conformational dimerization. Biochemistry, 47, 2008

Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
Descriptor:	COPPER (II) ION, MAGNESIUM ION, Plastocyanin
Authors:	Crowley, P.B, Matias, P.M, Mi, H, Firbank, S.J, Banfield, M.J, Dennison, C.
Deposit date:	2008-04-18
Release date:	2008-07-08
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.72 Å)
Cite:	Regulation of protein function: crystal packing interfaces and conformational dimerization. Biochemistry, 47, 2008

Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
Descriptor:	COPPER (I) ION, Plastocyanin, ZINC ION
Authors:	Crowley, P.B, Matias, P.M, Mi, H, Firbank, S.J, Banfield, M.J, Dennison, C.
Deposit date:	2008-04-18
Release date:	2008-07-08
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Regulation of protein function: crystal packing interfaces and conformational dimerization. Biochemistry, 47, 2008