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7USW
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BU of 7usw by Molmil
Structure of Expanded C. elegans TMC-1 complex
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jeong, H, Clark, S, Gouaux, E.
Deposit date:2022-04-26
Release date:2022-10-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
1Z98
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BU of 1z98 by Molmil
Crystal structure of the spinach aquaporin SoPIP2;1 in a closed conformation
Descriptor: CADMIUM ION, aquaporin
Authors:Tornroth-Horsefield, S, Hedfalk, K, Johanson, U, Karlsson, M, Neutze, R, Kjellbom, P.
Deposit date:2005-04-01
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural mechanism of plant aquaporin gating
Nature, 439, 2006
6D9G
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BU of 6d9g by Molmil
X-ray Structure of the FAB Fragment of 15B8, a Murine Monoclonal Antibody Specific for the Human Serotonin Transporter
Descriptor: Antibody heavy chain Fab, Antibody light chain Fab
Authors:Coleman, J.A, Yang, D, Gouaux, E.
Deposit date:2018-04-29
Release date:2019-04-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
5XLS
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BU of 5xls by Molmil
Crystal structure of UraA in occluded conformation
Descriptor: 12-TUNGSTOPHOSPHATE, URACIL, Uracil permease
Authors:Yu, X.Z, Yang, G.H, Yan, C.Y, Yan, N.
Deposit date:2017-05-11
Release date:2017-07-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters
Cell Res., 27, 2017
7LGU
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BU of 7lgu by Molmil
Structure of human prestin in the presence of NaCl
Descriptor: CHLORIDE ION, CHOLESTEROL, DECANE, ...
Authors:Ge, J, Gouaux, E.
Deposit date:2021-01-21
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Molecular mechanism of prestin electromotive signal amplification.
Cell, 184, 2021
7LGW
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BU of 7lgw by Molmil
Structure of human Prestin in nanodisc in the presence of NaCl
Descriptor: CHLORIDE ION, CHOLESTEROL, DECANE, ...
Authors:Ge, J, Gouaux, E.
Deposit date:2021-01-21
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular mechanism of prestin electromotive signal amplification.
Cell, 184, 2021
7LH3
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BU of 7lh3 by Molmil
Structure of human prestin in the presence of sodium sulfate
Descriptor: Prestin
Authors:Ge, J, Gouaux, E.
Deposit date:2021-01-21
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular mechanism of prestin electromotive signal amplification.
Cell, 184, 2021
7LH2
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BU of 7lh2 by Molmil
Structure of human prestin in the presence of sodium salicylate and sodium sulfate
Descriptor: 2-HYDROXYBENZOIC ACID, CHOLESTEROL, Prestin
Authors:Ge, J, Gouaux, E.
Deposit date:2021-01-21
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Molecular mechanism of prestin electromotive signal amplification.
Cell, 184, 2021
8T1P
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BU of 8t1p by Molmil
Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ADPVi: BmrCD_OC-ADPVi
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ...
Authors:Tang, Q, Mchaourab, H.S.
Deposit date:2023-06-02
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8SZC
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BU of 8szc by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-1HT/ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2023-05-29
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8T3K
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BU of 8t3k by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP2
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2023-06-07
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
7JG1
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BU of 7jg1 by Molmil
Dimeric Immunoglobin A (dIgA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ...
Authors:Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M.
Deposit date:2020-07-18
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structures of Secretory and dimeric Immunoglobulin A.
Elife, 9, 2020
7JG2
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BU of 7jg2 by Molmil
Secretory Immunoglobin A (SIgA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ...
Authors:Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M.
Deposit date:2020-07-18
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structures of Secretory and dimeric Immunoglobulin A.
Elife, 9, 2020
4Q13
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BU of 4q13 by Molmil
Apo Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant with a glucocorticoid receptor-interacting protein 1 NR box II peptide
Descriptor: Estrogen receptor, Glucocorticoid receptor-interacting protein 1 NR box II peptide
Authors:Fanning, S.W, Panchamukhi, S, Greene, G.L.
Deposit date:2014-04-02
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
4PXM
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BU of 4pxm by Molmil
The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide
Descriptor: ESTRADIOL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Fanning, S.W, Panchamukhi, S, Greene, G.L.
Deposit date:2014-03-24
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
4Q50
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BU of 4q50 by Molmil
The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with 4-hydroxytamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen receptor, SULFATE ION
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2014-04-15
Release date:2015-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
4EZC
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BU of 4ezc by Molmil
Crystal Structure of the UT-B Urea Transporter from Bos Taurus
Descriptor: OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Urea transporter 1, beta-D-glucopyranose, ...
Authors:Cao, Y, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2012-05-02
Release date:2012-06-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EZD
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BU of 4ezd by Molmil
Crystal Structure of the UT-B Urea Transporter from Bos Taurus Bound to Selenourea
Descriptor: OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Urea transporter 1, beta-D-glucopyranose, ...
Authors:Cao, Y, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2012-05-02
Release date:2012-06-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
5HD8
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BU of 5hd8 by Molmil
Crystal structure of disulfide cross-linked D417C ClC-ec1
Descriptor: CHLORIDE ION, FAB FRAGMENT (HEAVY CHAIN), FAB FRAGMENT (LIGHT CHAIN), ...
Authors:Mathews, I.I, Khantwal, C.M, Maduke, M.
Deposit date:2016-01-05
Release date:2017-01-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Conformational change in CLC transporters: beyond the rotation of Gluex
To be published
5D6M
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BU of 5d6m by Molmil
Mn(II)-loaded MnCcP.1
Descriptor: Cytochrome c peroxidase, mitochondrial, MANGANESE (II) ION, ...
Authors:Robinson, H, Gao, Y.-G, Hosseinzadeh, P, Lu, Y.
Deposit date:2015-08-12
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.653 Å)
Cite:Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions.
Biochemistry, 55, 2016
6B4C
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BU of 6b4c by Molmil
Structure of Viperin from Trichoderma virens
Descriptor: CITRATE ANION, SULFATE ION, Viperin
Authors:Huang, R.H, Selvadurai, K.
Deposit date:2017-09-26
Release date:2018-07-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Reconstitution and substrate specificity for isopentenyl pyrophosphate of the antiviral radical SAM enzyme viperin.
J.Biol.Chem., 293, 2018
3SKP
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BU of 3skp by Molmil
The structure of apo-human transferrin C-lobe with bound sulfate ions
Descriptor: SULFATE ION, Serotransferrin
Authors:Noinaj, N, Steere, A.N, Mason, A.B, Buchanan, S.K.
Deposit date:2011-06-22
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for iron piracy by pathogenic Neisseria.
Nature, 483, 2012
6BL6
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BU of 6bl6 by Molmil
Crystallization of lipid A transporter MsbA from Salmonella typhimurium
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Padayatti, P.S, Stanfield, R.L, Zhang, Q, Wilson, I.A, Lee, S.C.
Deposit date:2017-11-09
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
3CLL
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BU of 3cll by Molmil
Crystal structure of the Spinach Aquaporin SoPIP2;1 S115E mutant
Descriptor: Aquaporin
Authors:Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Trnroth-Horsefield, S.
Deposit date:2008-03-19
Release date:2009-02-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating.
J.Mol.Biol., 387, 2009
3CN6
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BU of 3cn6 by Molmil
Crystal structure of the Spinach Aquaporin SoPIP2;1 S274E mutant
Descriptor: Aquaporin, CADMIUM ION
Authors:Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Tornroth-Horsefield, S.
Deposit date:2008-03-25
Release date:2009-02-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating.
J.Mol.Biol., 387, 2009

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数据于2024-07-17公开中

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