6YXA
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![BU of 6yxa by Molmil](/molmil-images/mine/6yxa) | Structure of the bifunctional Rel enzyme from B. subtilis | Descriptor: | GTP pyrophosphokinase, MANGANESE (II) ION | Authors: | Pausch, P, Bange, G. | Deposit date: | 2020-04-30 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel. Cell Rep, 32, 2020
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6YVC
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5JAK
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![BU of 5jak by Molmil](/molmil-images/mine/5jak) | Crystal structure of the flagellar assembly factor FliW | Descriptor: | Flagellar assembly factor FliW | Authors: | Altegoer, F, Bange, G. | Deposit date: | 2016-04-12 | Release date: | 2016-08-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural basis for the CsrA-dependent modulation of translation initiation by an ancient regulatory protein. Proc.Natl.Acad.Sci.USA, 113, 2016
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5JRL
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5JQF
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![BU of 5jqf by Molmil](/molmil-images/mine/5jqf) | Crystal structure of the lasso peptide Sphingopyxin I (SpI) | Descriptor: | Sphingopyxin I | Authors: | Fage, C.D, Hegemann, J.D, Harms, K, Bange, G, Marahiel, M.A. | Deposit date: | 2016-05-04 | Release date: | 2016-09-14 | Last modified: | 2021-06-16 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase. Angew. Chem. Int. Ed. Engl., 55, 2016
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5J8Q
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5JRK
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![BU of 5jrk by Molmil](/molmil-images/mine/5jrk) | Crystal Structure of the Sphingopyxin I Lasso Peptide Isopeptidase SpI-IsoP (SeMet-derived) | Descriptor: | Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein, beta-D-glucopyranose | Authors: | Fage, C.D, Hegemann, J.D, Bange, G, Marahiel, M.A. | Deposit date: | 2016-05-06 | Release date: | 2016-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase. Angew.Chem.Int.Ed.Engl., 55, 2016
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7OJ2
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![BU of 7oj2 by Molmil](/molmil-images/mine/7oj2) | Bacillus subtilis IMPDH in complex with Ap4A | Descriptor: | GLYCEROL, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION | Authors: | Giammarinaro, P.I, Bange, G. | Deposit date: | 2021-05-13 | Release date: | 2022-09-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
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7OG5
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8A0A
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![BU of 8a0a by Molmil](/molmil-images/mine/8a0a) | Bacillus subtilis SPbeta prophage master regulator MrpR | Descriptor: | Bacillus subtilis SPbeta prophage master regulator MrpR | Authors: | Czech, L, Bange, G. | Deposit date: | 2022-05-27 | Release date: | 2023-06-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and functional characterization of MrpR, the master repressor of the Bacillus subtilis prophage SP beta. Nucleic Acids Res., 51, 2023
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8AJJ
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8AG8
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6TI2
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6TWJ
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6TWM
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![BU of 6twm by Molmil](/molmil-images/mine/6twm) | Product bound structure of the Ectoine utilization protein EutE (DoeB) from Ruegeria pomeroyi | Descriptor: | 2,4-DIAMINOBUTYRIC ACID, ACETATE ION, N-acetyl-L-2,4-diaminobutyric acid deacetylase, ... | Authors: | Mais, C.-N, Altegoer, F, Bange, G. | Deposit date: | 2020-01-13 | Release date: | 2020-05-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex. J.Biol.Chem., 295, 2020
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8AJK
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![BU of 8ajk by Molmil](/molmil-images/mine/8ajk) | Crystal structure of a C43S variant from the disulfide reductase MerA from Staphylococcus aureus | Descriptor: | FAD-containing oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Weiland, P, Altegoer, F, Bange, G. | Deposit date: | 2022-07-28 | Release date: | 2023-03-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | MerA functions as a hypothiocyanous acid reductase and defense mechanism in Staphylococcus aureus. Mol.Microbiol., 119, 2023
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6TWK
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![BU of 6twk by Molmil](/molmil-images/mine/6twk) | Substrate bound structure of the Ectoine utilization protein EutD (DoeA) from Halomonas elongata | Descriptor: | (2~{R})-4-azanyl-2-[[(1~{S})-1-oxidanylethyl]amino]butanoic acid, (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Ectoine hydrolase DoeA | Authors: | Mais, C.-N, Altegoer, F, Bange, G. | Deposit date: | 2020-01-13 | Release date: | 2020-05-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex. J.Biol.Chem., 295, 2020
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8BP7
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![BU of 8bp7 by Molmil](/molmil-images/mine/8bp7) | Citrate-bound hexamer of Synechococcus elongatus citrate synthase | Descriptor: | CITRIC ACID, Citrate synthase, MAGNESIUM ION, ... | Authors: | Mais, C.-N, Sendker, F, Bange, G. | Deposit date: | 2022-11-16 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature, 628, 2024
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6TWL
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5MAW
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5NJT
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![BU of 5njt by Molmil](/molmil-images/mine/5njt) | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Beckert, B, Abdelshahid, M, Schaefer, H, Steinchen, W, Arenz, S, Berninghausen, O, Beckmann, R, Bange, G, Turgay, K, Wilson, D.N. | Deposit date: | 2017-03-29 | Release date: | 2017-06-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. EMBO J., 36, 2017
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5NLA
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5AFF
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![BU of 5aff by Molmil](/molmil-images/mine/5aff) | Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA binding site | Descriptor: | RIBOSOMAL PROTEIN L11, RIBOSOMAL PROTEIN L5, SYMPORTIN 1 | Authors: | Calvino, F.R, Kharde, S, Wild, K, Bange, G, Sinning, I. | Deposit date: | 2015-01-21 | Release date: | 2015-04-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.398 Å) | Cite: | Symportin 1 Chaperones 5S Rnp Assembly During Ribosome Biogenesis by Occupying an Essential Rrna-Binding Site. Nat.Commun., 6, 2015
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5DED
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![BU of 5ded by Molmil](/molmil-images/mine/5ded) | Crystal structure of the small alarmone synthethase 1 from Bacillus subtilis bound to its product pppGpp | Descriptor: | GTP pyrophosphokinase YjbM, MAGNESIUM ION, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | Authors: | Steinchen, W, Schuhmacher, J.S, Altegoer, F, Bange, G. | Deposit date: | 2015-08-25 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.942 Å) | Cite: | Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone. Proc.Natl.Acad.Sci.USA, 112, 2015
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5DEC
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