2Z9V
| Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxamine | Descriptor: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Aspartate aminotransferase, GLYCEROL, ... | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | Deposit date: | 2007-09-26 | Release date: | 2007-11-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
|
|
2ZAA
| Crystal Structure of Family 7 Alginate Lyase A1-II' H191N/Y284F in Complex with Substrate (GGMG) | Descriptor: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, Alginate lyase, GLYCEROL | Authors: | Ogura, K, Yamasaki, M, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2007-10-02 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Substrate Recognition in Tunnel of Family 7 Alginate Lyase from Sphingomonas sp. A1 To be Published
|
|
2Z42
| Crystal Structure of Family 7 Alginate Lyase A1-II' from Sphingomonas sp. A1 | Descriptor: | Alginate lyase, SULFATE ION | Authors: | Ogura, K, Yamasaki, M, Hashimoto, W, Mikami, B, Murata, K. | Deposit date: | 2007-06-12 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Substrate Recognition by Family 7 Alginagte Lyase from Sphingomonas sp. A1 To be published
|
|
2ZAB
| Crystal Structure of Family 7 Alginate Lyase A1-II' Y284F in Cmplex with Product (GGG) | Descriptor: | Alginate lyase, GLYCEROL, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid | Authors: | Ogura, K, Yamasaki, M, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2007-10-02 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Substrate Recognition in Tunnel of Family 7 Alginate Lyase from Sphingomonas sp. A1 To be Published
|
|
2Z9X
| Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxyl-L-alanine | Descriptor: | 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, ALANINE, Aspartate aminotransferase, ... | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | Deposit date: | 2007-09-26 | Release date: | 2007-11-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
|
|
3AFL
| Crystal structure of exotype alginate lyase Atu3025 H531A complexed with alginate trisaccharide | Descriptor: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, Oligo alginate lyase | Authors: | Ochiai, A, Yamasaki, M, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2010-03-09 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Crystal structure of exotype alginate lyase Atu3025 from Agrobacterium tumefaciens J.Biol.Chem., 285, 2010
|
|
6B30
| Structure of RORgt in complex with a novel inverse agonist 1 | Descriptor: | N-[(1R)-1-(4-methoxyphenyl)-2-oxo-2-{[4-(trimethylsilyl)phenyl]amino}ethyl]-N-methyl-3-oxo-2,3-dihydro-1,2-oxazole-5-carboxamide, Nuclear receptor ROR-gamma | Authors: | Skene, R.J, Hoffman, I. | Deposit date: | 2017-09-20 | Release date: | 2018-01-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Discovery of orally efficacious ROR gamma t inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds. Bioorg. Med. Chem., 26, 2018
|
|
6B31
| Structure of RORgt in complex with a novel inverse agonist 2 | Descriptor: | (3S)-N~1~-(3-chloro-4-cyanophenyl)-N~5~-(1,3-diethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-6-yl)-3-methylpentanediamide, Nuclear receptor ROR-gamma | Authors: | Skene, R.J, Hoffman, I. | Deposit date: | 2017-09-20 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Identification of novel quinazolinedione derivatives as ROR gamma t inverse agonist. Bioorg. Med. Chem., 26, 2018
|
|
6B33
| Structure of RORgt in complex with a novel inverse agonist 3 | Descriptor: | (2R)-N~2~-(3-chloro-4-cyanophenyl)-N~4~-[3-(cyclopropylmethyl)-2,4-dioxo-1-(propan-2-yl)-1,2,3,4-tetrahydroquinazolin-6-yl]morpholine-2,4-dicarboxamide, Nuclear receptor ROR-gamma | Authors: | Skene, R.J, Hoffman, I, Snell, G. | Deposit date: | 2017-09-20 | Release date: | 2018-11-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Design and Synthesis of Conformationally Constrained ROR gamma t Inverse Agonists. Chemmedchem, 2019
|
|
6BR2
| Structure of RORgt in complex with a novel isoquinoline inverse agonist. | Descriptor: | (1R)-N-(4-tert-butyl-3-fluorophenyl)-6-methoxy-2-[(3-oxo-2,3-dihydro-1,2-oxazol-5-yl)acetyl]-1,2,3,4-tetrahydroisoquinoline-1-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Nuclear receptor ROR-gamma | Authors: | Skene, R.J, Hoffman, I. | Deposit date: | 2017-11-29 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor gamma t Inverse Agonist. J. Med. Chem., 61, 2018
|
|
6BR3
| Structure of RORgt in complex with a novel inverse agonist TAK-828. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Nuclear receptor ROR-gamma, {cis-3-[(5R)-5-[(7-fluoro-1,1-dimethyl-1H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridine-6(5H)-carbonyl]cyclobutyl}acetic acid | Authors: | Skene, R.J, Hoffman, I. | Deposit date: | 2017-11-29 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor gamma t Inverse Agonist. J. Med. Chem., 61, 2018
|
|
2ZOT
| |
2ZOU
| Crystal structure of human F-spondin reeler domain (fragment 2) | Descriptor: | 1,2-ETHANEDIOL, Spondin-1 | Authors: | Nagae, M, Nogi, T, Takagi, J. | Deposit date: | 2008-06-07 | Release date: | 2008-10-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of the F-spondin reeler domain reveals a unique beta-sandwich fold with a deformable disulfide-bonded loop Acta Crystallogr.,Sect.D, 64, 2008
|
|