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4H69
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BU of 4h69 by Molmil
Crystal Structure of the Allene Oxide Cyclase 2 from Physcomitrella patens complexed with substrate analog
Descriptor: (9Z)-11-{(2R,3S)-3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}undec-9-enoic acid, Allene oxide cyclase, ISOPROPYL ALCOHOL, ...
Authors:Neumann, P, Ficner, R.
Deposit date:2012-09-19
Release date:2012-10-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Physcomitrella patens AOC1 and AOC2: Insights into the Enzyme Mechanism and Differences in Substrate Specificity.
Plant Physiol., 160, 2012
3CGN
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BU of 3cgn by Molmil
Crystal Structure of thermophilic SlyD
Descriptor: Peptidyl-prolyl cis-trans isomerase, SULFATE ION
Authors:Neumann, P, Loew, C, Stubbs, M.T, Balbach, J.
Deposit date:2008-03-06
Release date:2009-03-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus
J.Mol.Biol., 398, 2010
5HSA
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BU of 5hsa by Molmil
Alcohol Oxidase AOX1 from Pichia Pastoris
Descriptor: ARABINO-FLAVIN-ADENINE DINUCLEOTIDE, Alcohol oxidase 1, CALCIUM ION, ...
Authors:Neumann, P, Ficner, R, Feussner, I, Koch, C.
Deposit date:2016-01-25
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of Alcohol Oxidase from Pichia pastoris.
Plos One, 11, 2016
3FT7
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BU of 3ft7 by Molmil
Crystal structure of an extremely stable dimeric protein from sulfolobus islandicus
Descriptor: GLYCEROL, Uncharacterized protein ORF56
Authors:Neumann, P, Loew, C, Weininger, U, Stubbs, M.T.
Deposit date:2009-01-12
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Stability Analysis of an Extremely Stable Dimeric DNA Binding Protein from Sulfolobus islandicus
Biochemistry, 48, 2009
3FD7
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BU of 3fd7 by Molmil
Crystal structure of Onconase C87A/C104A-ONC
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein P-30, ...
Authors:Neumann, P, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Stubbs, M.T.
Deposit date:2008-11-25
Release date:2009-12-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.531 Å)
Cite:Impact of the C-terminal disulfide bond on the folding and stability of onconase.
Chembiochem, 11, 2010
8ARU
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BU of 8aru by Molmil
Crystal Structure of human formylglycine generating enzyme
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Formylglycine-generating enzyme
Authors:Neumann, P, Dickmanns, A, Ficner, R, Rudolph, M.G.
Deposit date:2022-08-17
Release date:2023-08-23
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal Structure of human formylglycine generating enzyme E130A mutant
To be published
3MWQ
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BU of 3mwq by Molmil
Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor
Descriptor: GLYCEROL, Ribonuclease pancreatic, LINKER, ...
Authors:Neumann, P, Leich, F.
Deposit date:2010-05-06
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor
Febs J., 278, 2011
3MWR
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BU of 3mwr by Molmil
Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor
Descriptor: GLYCEROL, Ribonuclease pancreatic, LINKER, ...
Authors:Neumann, P, Leich, F.
Deposit date:2010-05-06
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor
Febs J., 278, 2011
4KGD
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BU of 4kgd by Molmil
High-resolution crystal structure of pyruvate oxidase from L. plantarum in complex with phosphate
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ...
Authors:Neumann, P, Tittmann, K.
Deposit date:2013-04-29
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Observation of a stable carbene at the active site of a thiamin enzyme.
Nat.Chem.Biol., 9, 2013
4KXX
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BU of 4kxx by Molmil
Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate
Descriptor: (2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Neumann, P, Luedtke, S, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4KXU
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BU of 4kxu by Molmil
Human transketolase in covalent complex with donor ketose D-fructose-6-phosphate
Descriptor: 1,2-ETHANEDIOL, D-SORBITOL-6-PHOSPHATE, MAGNESIUM ION, ...
Authors:Neumann, P, Luedtke, S, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4KXY
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BU of 4kxy by Molmil
Human transketolase in complex with ThDP analogue (R)-2-(1,2-dihydroxyethyl)-3-deaza-ThDP
Descriptor: 1,2-ETHANEDIOL, 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[(1R)-1,2-dihydroxyethyl]-3-methylthiophen-2-yl}ethyl trihydrogen diphosphate, CALCIUM ION, ...
Authors:Neumann, P, Luedtke, S, Erixon, K.M, Leeper, F, Kluger, R, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4KXW
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BU of 4kxw by Molmil
Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 2
Descriptor: 1,2-ETHANEDIOL, D-XYLITOL-5-PHOSPHATE, MAGNESIUM ION, ...
Authors:Neumann, P, Luedtke, S, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4KXV
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BU of 4kxv by Molmil
Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 1
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, D-XYLITOL-5-PHOSPHATE, ...
Authors:Neumann, P, Luedtke, S, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
3E7W
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BU of 3e7w by Molmil
Crystal structure of DLTA: Implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains
Descriptor: ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1, PHOSPHATE ION
Authors:Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T.
Deposit date:2008-08-19
Release date:2008-09-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
J.Biol.Chem., 283, 2008
3E7X
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BU of 3e7x by Molmil
Crystal structure of DLTA: implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains
Descriptor: ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1
Authors:Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T.
Deposit date:2008-08-19
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
J.Biol.Chem., 283, 2008
3EY6
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BU of 3ey6 by Molmil
Crystal structure of the FK506-binding domain of human FKBP38
Descriptor: FK506-binding protein 8
Authors:Parthier, C, Maestre-Martinez, M, Neumann, P, Edlich, F, Fischer, G, Luecke, C, Stubbs, M.T.
Deposit date:2008-10-19
Release date:2009-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding.
J.Mol.Recognit., 24, 2011
7NZJ
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BU of 7nzj by Molmil
Structure of bsTrmB apo
Descriptor: GLYCEROL, SODIUM ION, tRNA (guanine-N(7)-)-methyltransferase
Authors:Blersch, K.F, Ficner, R, Neumann, P.
Deposit date:2021-03-24
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021
7NYB
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BU of 7nyb by Molmil
TrmB complex with SAM
Descriptor: S-ADENOSYLMETHIONINE, tRNA (guanine-N(7)-)-methyltransferase
Authors:Blersch, K.F, Ficner, R, Neumann, P.
Deposit date:2021-03-22
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021
7NZI
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BU of 7nzi by Molmil
TrmB complex with SAH
Descriptor: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase
Authors:Blersch, K.F, Ficner, R, Neumann, P.
Deposit date:2021-03-24
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021
4RV7
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BU of 4rv7 by Molmil
Characterization of an essential diadenylate cyclase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Diadenylate cyclase, HEXANE-1,6-DIOL, ...
Authors:Dickmanns, A, Neumann, P, Ficner, R.
Deposit date:2014-11-25
Release date:2015-01-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Biochemical Analysis of the Essential Diadenylate Cyclase CdaA from Listeria monocytogenes.
J.Biol.Chem., 290, 2015
4RLE
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BU of 4rle by Molmil
Crystal structure of the c-di-AMP binding PII-like protein DarA
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, NICKEL (II) ION, Uncharacterized protein YaaQ
Authors:Dickmanns, A, Neumann, P, Ficner, R.
Deposit date:2014-10-16
Release date:2014-12-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA.
J.Biol.Chem., 290, 2015
1ICT
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BU of 1ict by Molmil
MONOCLINIC FORM OF HUMAN TRANSTHYRETIN COMPLEXED WITH THYROXINE (T4)
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN
Authors:Wojtczak, A, Neumann, P, Cody, V.
Deposit date:2001-04-02
Release date:2002-04-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a new polymorphic monoclinic form of human transthyretin at 3 A resolution reveals a mixed complex between unliganded and T4-bound tetramers of TTR.
Acta Crystallogr.,Sect.D, 57, 2001
2QKH
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BU of 2qkh by Molmil
Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP
Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, D(-)-TARTARIC ACID, Glucose-dependent insulinotropic polypeptide, ...
Authors:Parthier, C, Kleinschmidt, M, Neumann, P, Rudolph, R, Manhart, S, Schlenzig, D, Fanghanel, J, Rahfeld, J.-U, Demuth, H.-U, Stubbs, M.T.
Deposit date:2007-07-11
Release date:2007-08-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QC7
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BU of 2qc7 by Molmil
Crystal structure of the protein-disulfide isomerase related chaperone ERp29
Descriptor: Endoplasmic reticulum protein ERp29
Authors:Barak, N.N, Sevvana, M, Neumann, P, Malesevic, M, Naumann, K, Fischer, G, Sheldrick, G.M, Stubbs, M.T, Ferrari, D.M.
Deposit date:2007-06-19
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29.
J.Mol.Biol., 385, 2009

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