4GK6
| |
4HR3
| |
4I1Y
| |
4IJN
| |
4HDT
| |
4IV6
| |
4IZ9
| |
3GVC
| |
3GVG
| |
3GWC
| |
3H81
| |
2O8M
| Crystal structure of the S139A mutant of Hepatitis C Virus NS3/4A protease | Descriptor: | Protease, SODIUM ION, ZINC ION | Authors: | Fischmann, T.O, Prongay, A.J, Madison, V.M, Yao, N. | Deposit date: | 2006-12-12 | Release date: | 2007-10-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization J.Med.Chem., 50, 2007
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|
4EYE
| |
4DI1
| |
4DQ8
| |
4EGF
| |
4DIE
| |
4EO9
| |
4F3W
| |
4F47
| |
4DXL
| |
4ED4
| |
4EGE
| |
4EMD
| |
3HZU
| |