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Crystal structure of the N-terminal truncated PAS domain from the hERG potassium channel
Descriptor:	Potassium voltage-gated channel subfamily H member 2
Authors:	Adaixo, R, Morais-Cabral, J.H, Harley, C.A.
Deposit date:	2012-10-23
Release date:	2013-03-27
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.12 Å)
Cite:	Structural properties of PAS domains from the KCNH potassium channels Plos One, 8, 2013

4HQA

Crystal structure of PAS domain from the human ERG (hERG) potassium channel
Descriptor:	Potassium voltage-gated channel subfamily H member 2
Authors:	Adaixo, R, Morais-Cabral, J.H, Harley, C.A.
Deposit date:	2012-10-25
Release date:	2013-03-27
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (1.96 Å)
Cite:	Structural properties of PAS domains from the KCNH potassium channels Plos One, 8, 2013

4HP4

Crystal structure of PAS domain from the fruit-fly ELK potassium channel
Descriptor:	Eag-like K[+] channel, GLYCEROL, SULFATE ION
Authors:	Adaixo, R, Morais-Cabral, J.H.
Deposit date:	2012-10-23
Release date:	2013-03-27
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural properties of PAS domains from the KCNH potassium channels Plos One, 8, 2013

5BUT

Crystal structure of inactive conformation of KtrAB K+ transporter
Descriptor:	Ktr system potassium uptake protein A,Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, POTASSIUM ION
Authors:	Vieira-Pires, R.S, Morais-Cabral, J.H.
Deposit date:	2015-06-04
Release date:	2016-01-27
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (5.97 Å)
Cite:	Dissecting the Molecular Mechanism of Nucleotide-Dependent Activation of the KtrAB K+ Transporter. Plos Biol., 14, 2016

5FG8

Drosophila CaMKII-wt in complex with a fragment of the Eag potassium channel and Mg2+/ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II alpha chain, GLYCEROL, ...
Authors:	Castro-Rodrigues, A.F, Morais-Cabral, J.H.
Deposit date:	2015-12-20
Release date:	2016-12-28
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.955 Å)
Cite:	The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. J.Mol.Biol., 430, 2018

1VP6

M.loti ion channel cylic nucleotide binding domain
Descriptor:	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel
Authors:	Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H.
Deposit date:	2004-10-14
Release date:	2004-10-26
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell(Cambridge,Mass.), 119, 2004

1U12

M. loti cyclic nucleotide binding domain mutant
Descriptor:	IODIDE ION, POTASSIUM ION, SULFATE ION, ...
Authors:	Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H.
Deposit date:	2004-07-14
Release date:	2004-11-30
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel Cell(Cambridge,Mass.), 119, 2004

1K4D

Potassium Channel KcsA-Fab complex in low concentration of K+
Descriptor:	DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
Authors:	Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R.
Deposit date:	2001-10-07
Release date:	2001-11-14
Last modified:	2021-10-27
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature, 414, 2001

1K4C

Potassium Channel KcsA-Fab complex in high concentration of K+
Descriptor:	DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
Authors:	Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R.
Deposit date:	2001-10-07
Release date:	2001-11-14
Last modified:	2021-10-27
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature, 414, 2001

3CO2

Mlotik1 ion channel cyclic-nucleotide binding domain mutant
Descriptor:	Mlotik1 ion channel protein
Authors:	Clayton, G.M, Alteiri, S.L, Thomas, L.R, Morais-Cabral, J.H.
Deposit date:	2008-03-27
Release date:	2008-08-05
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Structural and Energetic Analysis of Activation by a Cyclic Nucleotide Binding Domain. J.Mol.Biol., 381, 2008

3CLP

M. loti cyclic-nucleotide binding domain mutant 2
Descriptor:	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein
Authors:	Clayton, G.M, Altieri, S.L, Thomas, L.R, Morais-Cabral, J.H.
Deposit date:	2008-03-19
Release date:	2008-08-05
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural and Energetic Analysis of Activation by a Cyclic Nucleotide Binding Domain. J.Mol.Biol., 381, 2008

3CL1

M. loti cyclic-nucleotide binding domain, cyclic-GMP bound
Descriptor:	CHLORIDE ION, CYCLIC GUANOSINE MONOPHOSPHATE, Mll3241 protein, ...
Authors:	Clayton, G.M, Alteiri, S.L, Thomas, L.R, Morais-Cabral, J.H.
Deposit date:	2008-03-18
Release date:	2008-08-05
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structural and Energetic Analysis of Activation by a Cyclic Nucleotide Binding Domain. J.Mol.Biol., 381, 2008

3BEH

Structure of a Bacterial Cyclic Nucleotide Regulated Ion Channel
Descriptor:	LAURYL DIMETHYLAMINE-N-OXIDE, Mll3241 protein, POTASSIUM ION
Authors:	Clayton, G.M, Morais-Cabral, J.H.
Deposit date:	2007-11-18
Release date:	2008-01-15
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel. Proc.Natl.Acad.Sci.USA, 105, 2008

5H9B

Drosophila CaMKII-wt in complex with a fragment of the Eag potassium channel and Mg2+/AMPPN
Descriptor:	AMP PHOSPHORAMIDATE, Calcium/calmodulin-dependent protein kinase II, isoform C, ...
Authors:	Castro-Rodrigues, A.F, Morais-Cabral, J.H.
Deposit date:	2015-12-27
Release date:	2017-01-11
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. J.Mol.Biol., 430, 2018

5HIT

Crystal Structure Analysis of Ca2+-calmodulin and a C-terminal EAG1 channel fragment
Descriptor:	CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily H member 1
Authors:	Marques-Carvalho, M.J, Morais-Cabral, J.H.
Deposit date:	2016-01-12
Release date:	2016-09-14
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Molecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium Channel. Structure, 24, 2016

5HU3

Drosophila CaMKII-D136N in complex with a phosphorylated fragment of the Eag potassium channel and Mg2+/ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II alpha chain, MAGNESIUM ION, ...
Authors:	Castro-Rodrigues, A.F, Morais-Cabral, J.H.
Deposit date:	2016-01-27
Release date:	2017-02-01
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (1.885 Å)
Cite:	The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. J.Mol.Biol., 430, 2018

5O7B

CRYSTAL STRUCTURE OF THE SLR0328 TYROSINE PHOSPHATASE WZB FROM SYNECHOCYSTIS SP. PCC 6803
Descriptor:	Putative low molecular weight protein-tyrosine-phosphatase slr0328
Authors:	Leite, J.P, Gales, L.
Deposit date:	2017-06-08
Release date:	2018-06-20
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (2.281 Å)
Cite:	The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803. Microbiologyopen, 2019

6EP3

Lar controls the expression of the Listeria monocytogenes agr system and mediates virulence.
Descriptor:	1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lmo0651 protein, ...
Authors:	Pinheiro, J, Lisboa, J, Carvalho, F, Carreaux, A, Santos, N, Cabral, J, Sousa, S, Cabanes, D.
Deposit date:	2017-10-10
Release date:	2018-07-25
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	MouR controls the expression of the Listeria monocytogenes Agr system and mediates virulence. Nucleic Acids Res., 46, 2018

2ZD9

Structure of a Bacterial Cyclic-Nucleotide Regulated Ion Channel
Descriptor:	Mll3241 protein, POTASSIUM ION
Authors:	Clayton, G.M, Cabral-Morais, J.M.
Deposit date:	2007-11-21
Release date:	2008-12-02
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (4 Å)
Cite:	Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel. Proc.Natl.Acad.Sci.USA, 105, 2008

1BEB

BOVINE BETA-LACTOGLOBULIN, LATTICE X
Descriptor:	BETA-LACTOGLOBULIN, SULFATE ION
Authors:	Brownlow, S, Morais-Cabral, J.H, Sawyer, L.
Deposit date:	1996-12-20
Release date:	1997-05-15
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Bovine beta-lactoglobulin at 1.8 A resolution--still an enigmatic lipocalin. Structure, 5, 1997

6S5B

Non-square conformation of KtrA R16K mutant ring with bound ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A
Authors:	Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H.
Deposit date:	2019-07-01
Release date:	2020-01-08
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (3.052 Å)
Cite:	Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019

6S7R

Non-square conformations of KtrA R16A mutant rings with bound ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A
Authors:	Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H.
Deposit date:	2019-07-05
Release date:	2020-01-08
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (3.73 Å)
Cite:	Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019

6S5D

Square conformation of KtrA R16A mutant ring with bound ATP
Descriptor:	ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, MAGNESIUM ION
Authors:	Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H.
Deposit date:	2019-07-01
Release date:	2020-01-08
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (3.393 Å)
Cite:	Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019

6S5G

Non-square conformation of KtrA A80P mutant ring with bound ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A
Authors:	Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H.
Deposit date:	2019-07-01
Release date:	2020-01-08
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (4.33 Å)
Cite:	Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019

6S5E

Non-square conformation of KtrA A80P mutant ring with bound ATP
Descriptor:	ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A
Authors:	Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H.
Deposit date:	2019-07-01
Release date:	2020-01-08
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (3.893 Å)
Cite:	Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019

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