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4LK4
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BU of 4lk4 by Molmil
Structure of Vibrio cholerae VesB protease
Descriptor: VESB protease
Authors:Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
Deposit date:2013-07-05
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional and Structural Characterization of Vibrio cholerae Extracellular Serine Protease B, VesB.
J.Biol.Chem., 289, 2014
4KG7
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BU of 4kg7 by Molmil
Structure of MycP3 protease from the type VII (ESX-3) secretion system.
Descriptor: CHLORIDE ION, Peptidase S8 and S53, subtilisin, ...
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2013-04-28
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
5SXL
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BU of 5sxl by Molmil
Structure of EspG3 chaperone from the type VII (ESX-3) secretion system, space group P3221
Descriptor: ESX-3 secretion-associated protein EspG3
Authors:Korotkov, K.V.
Deposit date:2016-08-09
Release date:2016-08-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5VBA
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BU of 5vba by Molmil
Structure of EspG1 chaperone from the type VII (ESX-1) secretion system determined with the assistance of N-terminal T4 lysozyme fusion
Descriptor: CHLORIDE ION, Lysozyme, ESX-1 secretion-associated protein EspG1 chimera
Authors:Korotkov, K.V.
Deposit date:2017-03-29
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
6PUX
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BU of 6pux by Molmil
Homoserine transacetylase MetX from Mycobacterium tuberculosis
Descriptor: CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ...
Authors:Chaton, C.T, Korotkov, K.V.
Deposit date:2019-07-18
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site.
Sci Rep, 9, 2019
6XMV
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BU of 6xmv by Molmil
The crystal structure of Neisseria gonorrhoeae DolP (NGO1985)
Descriptor: CHLORIDE ION, Hemolysin,Endolysin
Authors:Li, J, Peterson Brown, L.E, Reed, R.W, Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V.
Deposit date:2020-06-30
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structure and function of a new component of Bam complex in Neisseria
To Be Published
6BLK
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BU of 6blk by Molmil
Mycobacterial sensor histidine kinase MprB
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Signal transduction histidine-protein kinase/phosphatase mprB
Authors:Li, J, Korotkova, N, Korotkov, K.V.
Deposit date:2017-11-10
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:Mycobacterial sensor histidine kinase MprB
to be published
5DEO
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BU of 5deo by Molmil
Mycobacterium abscessus NadD in complex with nicotinic acid adenine dinucleotide
Descriptor: NICOTINIC ACID ADENINE DINUCLEOTIDE, Nicotinate-nucleotide adenylyltransferase
Authors:Reed, R.W, Korotkov, K.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-08-25
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Mycobacterium abscessus NadD in complex with nicotinic acid adenine dinucleotide
to be published
5DB4
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BU of 5db4 by Molmil
Mycobacterium abscessus NadD in complex with Mg-ATP, space group I41
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nicotinate-nucleotide adenylyltransferase
Authors:Reed, R.W, Korotkov, K.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-08-20
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Mycobacterium abscessus NadD in complex with Mg-ATP, space group I41
to be published
5I01
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BU of 5i01 by Molmil
Structure of phosphoheptose isomerase GmhA from Neisseria gonorrhoeae
Descriptor: Phosphoheptose isomerase, ZINC ION
Authors:Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V.
Deposit date:2016-02-03
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Functional and structural studies on the Neisseria gonorrhoeae GmhA, the first enzyme in the glycero-manno-heptose biosynthesis pathways, demonstrate a critical role in lipooligosaccharide synthesis and gonococcal viability.
Microbiologyopen, 6, 2017
6O93
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BU of 6o93 by Molmil
D-alanyl transferase DltD from Enterococcus faecalis
Descriptor: CHLORIDE ION, D-alanyl transferase DltD, GLYCEROL, ...
Authors:Shakhashiro, M, Korotkov, K.V.
Deposit date:2019-03-12
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.178 Å)
Cite:D-alanyl transferase DltD from Enterococcus faecalis
To Be Published
6PFX
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BU of 6pfx by Molmil
D-alanyl transferase DltD from Enterococcus faecium
Descriptor: D-alanyl transferase DltD, GLYCEROL
Authors:Shakhashiro, M, Korotkov, K.V.
Deposit date:2019-06-22
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:D-alanyl transferase DltD from Enterococcus faecium
To Be Published
6DGM
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BU of 6dgm by Molmil
Streptococcus pyogenes phosphoglycerol transferase GacH in complex with sn-glycerol-1-phosphate
Descriptor: CALCIUM ION, MANGANESE (II) ION, Phosphoglycerol transferase GacH, ...
Authors:Edgar, R.J, Korotkova, N, Korotkov, K.V.
Deposit date:2018-05-17
Release date:2018-06-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides.
Nat.Chem.Biol., 15, 2019
6DQ3
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BU of 6dq3 by Molmil
Streptococcus pyogenes deacetylase PplD in complex with acetate
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, IMIDAZOLE, ...
Authors:Li, J, Korotkova, N, Korotkov, K.V.
Deposit date:2018-06-10
Release date:2019-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides
Nat Commun, 13, 2022
6VHR
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BU of 6vhr by Molmil
Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group I422
Descriptor: ESX-3 secretion-associated protein EspG3, PE family immunomodulator PE5, PPE family protein PPE4
Authors:Williamson, Z.A, Korotkov, K.V.
Deposit date:2020-01-10
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:PE5-PPE4-EspG3heterotrimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems.
J.Biol.Chem., 295, 2020
6UUJ
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BU of 6uuj by Molmil
Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group P212121
Descriptor: ESX-3 secretion-associated protein EspG3, PE family immunomodulator PE5, PPE family protein PPE4
Authors:Williamson, Z.A, Korotkov, K.V.
Deposit date:2019-10-30
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:PE5-PPE4-EspG3heterotrimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems.
J.Biol.Chem., 295, 2020
6BQM
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BU of 6bqm by Molmil
Secreted serine protease VesC from Vibrio cholerae
Descriptor: serine protease VesC
Authors:Park, Y.J, Korotkov, K.V, Delarosa, J.R, Turley, S, DiMaio, F, Hol, W.G.J.
Deposit date:2017-11-28
Release date:2018-11-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease.
Msphere, 5, 2020
6VJ5
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BU of 6vj5 by Molmil
Structure of PE25-PPE41(A124L) in complex with EspG5 chaperone from the type VII (ESX-5) secretion system
Descriptor: CHLORIDE ION, ESX-5 secretion-associated protein EspG5, PE-PGRS family protein PE25, ...
Authors:Williamson, Z.A, Korotkov, K.V.
Deposit date:2020-01-14
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis of diverse substrate recognition by EspG5 chaperone from mycobacterial ESX-5 Type VII Secretion System.
To Be Published
6BUV
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BU of 6buv by Molmil
Structure of Mycobacterium tuberculosis NadD in complex with inhibitor [(1~{R},2~{R},5~{S})-5-methyl-2-propan-2-yl-cyclohexyl] 2-[3-methyl-2-(phenoxymethyl)benzimidazol-1-yl]ethanoate
Descriptor: 1-methyl-3-(2-{[(1R,2R,5S)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxoethyl)-2-(phenoxymethyl)-1H-1,3-benzimidazol-3-ium, CHLORIDE ION, SODIUM ION, ...
Authors:Rodionova, I.A, Reed, R.W, Sorci, L, Osterman, A.L, Korotkov, K.V.
Deposit date:2017-12-11
Release date:2018-12-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase.
Acs Chem.Biol., 14, 2019
3CFI
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BU of 3cfi by Molmil
Nanobody-aided structure determination of the EPSI:EPSJ pseudopilin heterdimer from Vibrio Vulnificus
Descriptor: CHLORIDE ION, Nanobody NBEPSIJ_11, Type II secretory pathway, ...
Authors:Lam, A.Y, Pardon, E, Korotkov, K.V, Steyaert, J, Hol, W.G.J.
Deposit date:2008-03-03
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.
J.Struct.Biol., 166, 2009
3C1Q
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BU of 3c1q by Molmil
The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, CHLORIDE ION, ...
Authors:Abendroth, J, Mitchell, D.D, Korotkov, K.V, Kreeger, A, Hol, W.G.J.
Deposit date:2008-01-24
Release date:2009-02-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
J.Struct.Biol., 166, 2009
4XY3
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BU of 4xy3 by Molmil
Structure of ESX-1 secreted protein EspB
Descriptor: ESX-1 secretion-associated protein EspB
Authors:Wagner, J.M, Korotkov, K.V.
Deposit date:2015-02-01
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XXX
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BU of 4xxx by Molmil
Structure of PE-PPE domains of ESX-1 secreted protein EspB, C2221
Descriptor: CHLORIDE ION, ESX-1 secretion-associated protein EspB, GLYCEROL
Authors:Piton, J, Pojer, F, Korotkov, K.V.
Deposit date:2015-01-30
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
6CYZ
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BU of 6cyz by Molmil
Mycobacterial homoserine kinase ThrB in complex with AMPPNP
Descriptor: CHLORIDE ION, Homoserine kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Li, J, Korotkov, K.V.
Deposit date:2018-04-07
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Mycobacterial homoserine kinase ThrB
To Be Published
6DZS
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BU of 6dzs by Molmil
Mycobacterial homoserine dehydrogenase ThrA in complex with NADP
Descriptor: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Chaton, C.T, Rodriguez, E.S, Korotkov, K.V.
Deposit date:2018-07-05
Release date:2018-07-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of mycobacterial homoserine dehydrogenase ThrA
To be Published

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