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Structure of hSTING in complex with novel carbocyclic pyrimidine CDN-2
Descriptor:	(2R,5R,7R,8R,10S,12aR,14R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2,10,16-trihydroxy-14-[(pyrimidin-4-yl)oxy]decahydro-2H,10H-5,8-methano-2lambda~5~,10lambda~5~-cyclopenta[l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
Authors:	Skene, R.J.
Deposit date:	2020-11-29
Release date:	2022-02-09
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route. J.Med.Chem., 64, 2021