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6ZI0
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BU of 6zi0 by Molmil
Crystal structure of the isolated H. influenzae VapD toxin (wildtype)
Descriptor: Endoribonuclease VapD
Authors:Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E.
Deposit date:2020-06-24
Release date:2020-10-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System.
Structure, 29, 2021
7QOC
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BU of 7qoc by Molmil
Se-Met derivative structure of a small alarmone hydrolase (RelH) from Corynebacterium glutamicum
Descriptor: Guanosine polyphosphate pyrophosphohydrolases/synthetases, MAGNESIUM ION
Authors:Bisiak, F, Brodersen, D.E, Chrenkova, A.
Deposit date:2021-12-23
Release date:2022-07-13
Last modified:2022-07-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response.
J.Biol.Chem., 298, 2022
5IQQ
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BU of 5iqq by Molmil
Crystal structure of the human RBM7 RRM domain
Descriptor: RNA-binding protein 7
Authors:Sofos, N, Winkler, M.B.L, Brodersen, D.E.
Deposit date:2016-03-11
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:RRM domain of human RBM7: purification, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 72, 2016
4R71
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BU of 4r71 by Molmil
Structure of the Qbeta holoenzyme complex in the P1211 crystal form
Descriptor: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ...
Authors:Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R.
Deposit date:2014-08-26
Release date:2015-09-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural basis for RNA-genome recognition during bacteriophage Q beta replication.
Nucleic Acids Res., 43, 2015
1HR0
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BU of 1hr0 by Molmil
CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Morgan-Warren, R.J, Wimberly, B.T, Ramakrishnan, V.
Deposit date:2000-12-20
Release date:2001-01-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of an initiation factor bound to the 30S ribosomal subunit.
Science, 291, 2001
6EX0
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BU of 6ex0 by Molmil
Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to pppGpp in the post-catalytic state
Descriptor: FE (II) ION, GTP pyrophosphokinase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2017-11-07
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.
J. Biol. Chem., 293, 2018
6EWZ
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BU of 6ewz by Molmil
Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to AMPCPP and GTP in the pre-catalytic state
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, FE (III) ION, GTP pyrophosphokinase, ...
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2017-11-07
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.
J. Biol. Chem., 293, 2018
6EXP
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BU of 6exp by Molmil
Crystal structure of the SIRV3 AcrID1 (gp02) anti-CRISPR protein
Descriptor: SIRV3 AcrID1 (gp02) anti-CRISPR protein
Authors:He, F, Bhoobalan-Chitty, Y, Van, L.B, Kjeldsen, A.L, Dedola, M, Makarova, K.S, Koonin, E.V, Brodersen, D.E, Peng, X.
Deposit date:2017-11-08
Release date:2018-01-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity.
Nat Microbiol, 3, 2018
6GFM
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BU of 6gfm by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (pppGpp-form)
Descriptor: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
Authors:Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
Deposit date:2018-05-01
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6GFL
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BU of 6gfl by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (apo form)
Descriptor: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase
Authors:Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
Deposit date:2018-05-01
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6GW6
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BU of 6gw6 by Molmil
Structure of the Pseudomonas putida RES-Xre toxin-antitoxin complex
Descriptor: GLYCEROL, IMIDAZOLE, RES toxin, ...
Authors:Senissar, M, Brodersen, D.E.
Deposit date:2018-06-22
Release date:2018-10-24
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD.
Mol. Microbiol., 111, 2019
3HFN
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BU of 3hfn by Molmil
Crystal Structure of an Hfq protein from Anabaena sp.
Descriptor: Asl2047 protein
Authors:Boggild, A, Overgaard, M, Valentin-Hansen, P, Brodersen, D.E.
Deposit date:2009-05-12
Release date:2009-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Cyanobacteria contain a structural homologue of the Hfq protein with altered RNA-binding properties.
Febs J., 276, 2009
5K8J
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BU of 5k8j by Molmil
Structure of Caulobacter crescentus VapBC1 (apo form)
Descriptor: GLYCEROL, Ribonuclease VapC, VapB family protein
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
3HFO
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BU of 3hfo by Molmil
Crystal Structure of an Hfq protein from Synechocystis sp.
Descriptor: Ssr3341 protein
Authors:Boggild, A, Overgaard, M, Valentin-Hansen, P, Brodersen, D.E.
Deposit date:2009-05-12
Release date:2009-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Cyanobacteria contain a structural homologue of the Hfq protein with altered RNA-binding properties.
Febs J., 276, 2009
5L6M
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BU of 5l6m by Molmil
Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form)
Descriptor: GLYCEROL, MALONATE ION, Ribonuclease VapC, ...
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
5L6L
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BU of 5l6l by Molmil
Structure of Caulobacter crescentus VapBC1 bound to operator DNA
Descriptor: DNA (27-MER), Ribonuclease VapC, VapB family protein
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
4V4R
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BU of 4v4r by Molmil
Crystal structure of the whole ribosomal complex.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-09-30
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.9 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V4S
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BU of 4v4s by Molmil
Crystal structure of the whole ribosomal complex.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-10-12
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.76 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V4T
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BU of 4v4t by Molmil
Crystal structure of the whole ribosomal complex with a stop codon in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-10-12
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.46 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V7K
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BU of 4v7k by Molmil
Structure of RelE nuclease bound to the 70S ribosome (postcleavage state)
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
Deposit date:2009-11-02
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
7AB3
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BU of 7ab3 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S57A)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB5
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BU of 7ab5 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT D233Q)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB4
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BU of 7ab4 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S59A)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
6ZN8
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BU of 6zn8 by Molmil
Crystal structure of the H. influenzae VapXD toxin-antitoxin complex
Descriptor: Endoribonuclease VapD, VapX
Authors:Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E.
Deposit date:2020-07-06
Release date:2020-11-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.211 Å)
Cite:Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System.
Structure, 29, 2021
1FJG
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BU of 1fjg by Molmil
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V.
Deposit date:2000-08-08
Release date:2000-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000

221051

数据于2024-06-12公开中

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