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1TT3
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BU of 1tt3 by Molmil
NMR soulution structure of omega-conotoxin [K10]MVIIA
Descriptor: Omega-conotoxin MVIIa
Authors:Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J.
Deposit date:2004-06-21
Release date:2004-07-06
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
1TU6
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Cathepsin K complexed with a ketoamide inhibitor
Descriptor: Cathepsin K, SULFATE ION, [1-(4-FLUOROBENZYL)CYCLOBUTYL]METHYL (1S)-1-[OXO(1H-PYRAZOL-5-YLAMINO)ACETYL]PENTYLCARBAMATE
Authors:Barrett, D.G, Catalano, J.G, Deaton, D.N, Hassell, A.M, Long, S.T, Miller, A.B, Miller, L.R, Shewchuk, L.M, Wells-Knecht, K.J, Wright, L.L.
Deposit date:2004-06-24
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with improved pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions
BIOORG.MED.CHEM.LETT., 14, 2004
1UB6
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BU of 1ub6 by Molmil
Crystal structure of Antibody 19G2 with sera ligand
Descriptor: antibody 19G2, alpha chain, beta chain
Authors:Beuscher, A.B, Wirsching, P, Lerner, R.A, Janda, K, Stevens, R.C.
Deposit date:2003-03-30
Release date:2004-04-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structure and Dynamics of Blue Fluorescent Antibody 19G2 at Blue and Violet Fluorescent Temperatures
To be published
1W9T
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BU of 1w9t by Molmil
Structure of a beta-1,3-glucan binding CBM6 from Bacillus halodurans in complex with xylobiose
Descriptor: BH0236 PROTEIN, SODIUM ION, alpha-D-xylopyranose, ...
Authors:Boraston, A.B, van Bueren, A.L.
Deposit date:2004-10-18
Release date:2004-11-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Family 6 Carbohydrate Binding Modules Recognize the Non-Reducing End of Beta-1,3-Linked Glucans by Presenting a Unique Ligand Binding Surface
J.Biol.Chem., 280, 2005
1W9S
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Structure of a beta-1,3-glucan binding CBM6 from Bacillus halodurans
Descriptor: BH0236 PROTEIN, GLYCEROL, SODIUM ION
Authors:Boraston, A.B, van Bueren, A.L.
Deposit date:2004-10-18
Release date:2004-11-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Family 6 Carbohydrate Binding Modules Recognize the Non-Reducing End of Beta-1,3-Linked Glucans by Presenting a Unique Ligand Binding Surface
J.Biol.Chem., 280, 2005
1B2W
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BU of 1b2w by Molmil
COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
Descriptor: PROTEIN (ANTIBODY (HEAVY CHAIN)), PROTEIN (ANTIBODY (LIGHT CHAIN))
Authors:Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasquez, M, Queen, C, Ramsland, P.A, Edmundson, A.B.
Deposit date:1998-12-01
Release date:1999-05-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
1B4J
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BU of 1b4j by Molmil
COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
Descriptor: ANTIBODY
Authors:Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasques, M, Queen, C, Ramsland, P.A, Edmundson, A.B.
Deposit date:1998-12-22
Release date:1999-06-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
1AQK
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THREE-DIMENSIONAL STRUCTURE OF A HUMAN FAB WITH HIGH AFFINITY FOR TETANUS TOXOID
Descriptor: FAB B7-15A2
Authors:Faber, C, Fan, Z, Edmundson, A.B.
Deposit date:1997-07-30
Release date:1998-02-04
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Three-dimensional structure of a human Fab with high affinity for tetanus toxoid.
Immunotechnology, 3, 1998
1WBH
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BU of 1wbh by Molmil
Crystal structure of the E45N mutant from KDPG aldolase from Escherichia coli
Descriptor: KHG/KDPG ALDOLASE, PHOSPHATE ION
Authors:Fullerton, S.W.B, Merkel, A.B, Naismith, J.H.
Deposit date:2004-11-01
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem., 14, 2006
1W9W
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Structure of a beta-1,3-glucan binding CBM6 from Bacillus halodurans in complex with laminarihexaose
Descriptor: BH0236 PROTEIN, SODIUM ION, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose
Authors:Boraston, A.B, van Bueren, A.L.
Deposit date:2004-10-19
Release date:2004-11-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Family 6 Carbohydrate Binding Modules Recognize the Non-Reducing End of Beta-1,3-Linked Glucans by Presenting a Unique Ligand Binding Surface
J.Biol.Chem., 280, 2005
1WA3
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BU of 1wa3 by Molmil
Mechanism of the Class I KDPG aldolase
Descriptor: 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE, PYRUVIC ACID, SULFATE ION
Authors:Fullerton, S.W.B, Griffiths, J.S, Merkel, A.B, Wymer, N.J, Hutchins, M.J, Fierke, C.A, Toone, E.J, Naismith, J.H.
Deposit date:2004-10-22
Release date:2005-01-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem., 14, 2006
1WAU
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BU of 1wau by Molmil
Structure of KDPG Aldolase E45N mutant
Descriptor: KHG/KDPG ALDOLASE, SULFATE ION
Authors:Merkel, A.B, Naismith, J.H.
Deposit date:2004-10-28
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem., 14, 2006
1W0N
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BU of 1w0n by Molmil
Structure of uncomplexed Carbohydrate Binding Domain CBM36
Descriptor: CALCIUM ION, ENDO-1,4-BETA-XYLANASE D, MAGNESIUM ION, ...
Authors:Jamal, S, Boraston, A.B, Davies, G.J.
Deposit date:2004-06-09
Release date:2004-10-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (0.8 Å)
Cite:Ab Initio Structure Determination and Functional Characterization of Cbm36: A New Family of Calcium-Dependent Carbohydrate Binding Modules
Structure, 12, 2004
1UX7
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Carbohydrate-Binding Module CBM36 in complex with calcium and xylotriose
Descriptor: CALCIUM ION, ENDO-1,4-BETA-XYLANASE D, SULFATE ION, ...
Authors:Davies, G.J, Boraston, A.B, Jamal, S.
Deposit date:2004-02-19
Release date:2004-10-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Ab Initio Structure Determination and Functional Characterization of Cbm36: A New Family of Calcium-Dependent Carbohydrate Binding Modules
Structure, 12, 2004
1T66
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BU of 1t66 by Molmil
The structure of FAB with intermediate affinity for fluorescein.
Descriptor: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, immunoglobulin heavy chain, immunoglobulin light chain
Authors:Terzyan, S, Ramsland, P.A, Voss Jr, E.W, Herron, J.N, Edmundson, A.B.
Deposit date:2004-05-05
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional Structures of Idiotypically Related Fabs with Intermediate and High Affinity for Fluorescein.
J.Mol.Biol., 339, 2004
1A8F
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BU of 1a8f by Molmil
HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
Descriptor: CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN
Authors:Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N.
Deposit date:1998-03-25
Release date:1998-06-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
1A8P
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BU of 1a8p by Molmil
FERREDOXIN REDUCTASE FROM AZOTOBACTER VINELANDII
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADPH:FERREDOXIN OXIDOREDUCTASE
Authors:Prasad, G.S, Kresge, N, Muhlberg, A.B, Shaw, A, Jung, Y.S, Burgess, B.K, Stout, C.D.
Deposit date:1998-03-28
Release date:1998-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of NADPH:ferredoxin reductase from Azotobacter vinelandii.
Protein Sci., 7, 1998
1B6B
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BU of 1b6b by Molmil
MELATONIN BIOSYNTHESIS: THE STRUCTURE OF SEROTONIN N-ACETYLTRANSFERASE AT 2.5 A RESOLUTION SUGGESTS A CATALYTIC MECHANISM
Descriptor: PROTEIN (ARYLALKYLAMINE N-ACETYLTRANSFERASE)
Authors:Hickman, A.B, Klein, D.C, Dyda, F.
Deposit date:1999-01-13
Release date:2000-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism.
Mol.Cell, 3, 1999
1B3E
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BU of 1b3e by Molmil
HUMAN SERUM TRANSFERRIN, N-TERMINAL LOBE, EXPRESSED IN PICHIA PASTORIS
Descriptor: CARBONATE ION, FE (III) ION, PROTEIN (SERUM TRANSFERRIN)
Authors:Bewley, M.C, Tam, B.M, Grewal, J, He, S, Shewry, S, Murphy, M.E.P, Mason, A.B, Woodworth, R.C, Baker, E.N, Macgillivray, R.T.A.
Deposit date:1998-12-09
Release date:1999-03-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32.
Biochemistry, 38, 1999
1UY4
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BU of 1uy4 by Molmil
Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
Descriptor: CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, GLYCEROL, ...
Authors:Van Bueren, A.L, Boraston, A.B.
Deposit date:2004-03-01
Release date:2004-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Binding Sub-Site Dissection of a Carbohydrate-Binding Module Reveals the Contribution of Entropy to Oligosaccharide Recognition at "Non-Primary" Binding Subsites.
J.Mol.Biol., 340, 2004
1UY3
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BU of 1uy3 by Molmil
Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
Descriptor: CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, GLYCEROL, ...
Authors:Van Bueren, A.L, Boraston, A.B.
Deposit date:2004-03-01
Release date:2004-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Binding Sub-Site Dissection of a Carbohydrate-Binding Module Reveals the Contribution of Entropy to Oligosaccharide Recognition at "Non-Primary" Binding Subsites.
J.Mol.Biol., 340, 2004
1UY1
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BU of 1uy1 by Molmil
Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
Descriptor: CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, GLYCEROL, ...
Authors:Van Bueren, A.L, Boraston, A.B.
Deposit date:2004-03-01
Release date:2004-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding Sub-Site Dissection of a Carbohydrate-Binding Module Reveals the Contribution of Entropy to Oligosaccharide Recognition at "Non-Primary" Binding Subsites.
J.Mol.Biol., 340, 2004
1SZP
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BU of 1szp by Molmil
A Crystal Structure of the Rad51 Filament
Descriptor: DNA repair protein RAD51, SULFATE ION
Authors:Conway, A.B, Lynch, T.W, Zhang, Y, Fortin, G.S, Symington, L.S, Rice, P.A.
Deposit date:2004-04-06
Release date:2004-07-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structure of a Rad51 filament.
Nat.Struct.Mol.Biol., 11, 2004
1T8I
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Human DNA Topoisomerase I (70 Kda) In Complex With The Poison Camptothecin and Covalent Complex With A 22 Base Pair DNA Duplex
Descriptor: 4-ETHYL-4-HYDROXY-1,12-DIHYDRO-4H-2-OXA-6,12A-DIAZA-DIBENZO[B,H]FLUORENE-3,13-DIONE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ...
Authors:Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B.
Deposit date:2004-05-12
Release date:2005-05-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
1A8C
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PRIMARY SEQUENCE AND SOLUTION CONFORMATION OF FERROCYTOCHROME C-552 FROM NITROSOMONAS EUROPAEA, NMR, MEAN STRUCTURE REFINED WITHOUT HYDROGEN BOND CONSTRAINTS
Descriptor: FERROCYTOCHROME C-552, HEME C
Authors:Timkovich, R, Bergmann, D, Arciero, D.M, Hooper, A.B.
Deposit date:1998-03-23
Release date:1998-10-21
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Primary sequence and solution conformation of ferrocytochrome c-552 from Nitrosomonas europaea.
Biophys.J., 75, 1998

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