7HBF
 
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12938 | | Descriptor: | Heat shock protein HSP 90-alpha, {3-[(pyridin-2-yl)oxy]phenyl}methanol | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAZ
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12919 | | Descriptor: | (2-phenoxyphenyl)methanol, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HBJ
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13498 | | Descriptor: | 6-(4-chloro-3-methylphenoxy)pyridin-3-amine, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HC2
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 2X-5009 | | Descriptor: | Heat shock protein HSP 90-alpha, N-(pyridin-4-yl)cyclopropanecarboxamide | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7H9Q
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13944 | | Descriptor: | 5-fluoro-2-methylbenzamide, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7H9U
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12864 | | Descriptor: | 5-chloranylthiophene-2-sulfonamide, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAI
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-5525 | | Descriptor: | 2-(3-bromophenyl)-5-methyl-1,3,4-oxadiazole, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAO
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13777 | | Descriptor: | (3M)-3-(1H-pyrazol-1-yl)benzonitrile, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HA2
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14256 | | Descriptor: | 3-amino-4-methylbenzamide, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HA5
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-3550 | | Descriptor: | 1-[(4-bromophenyl)methyl]-1,4-diazepane, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAB
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12700 | | Descriptor: | (morpholin-4-yl)(phenyl)methanone, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAU
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13098 | | Descriptor: | Heat shock protein HSP 90-alpha, [2-(4-methylpiperazin-1-yl)phenyl]methanol | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HB8
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13480 | | Descriptor: | Heat shock protein HSP 90-alpha, N-[(1R,2R,4S)-bicyclo[2.2.1]hept-5-en-2-yl]-N-methylthiophene-2-carboxamide | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAK
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-6793 | | Descriptor: | 8-fluoro-2-methylquinolin-4-ol, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAG
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14186 | | Descriptor: | (3M)-3-(1H-imidazol-1-yl)benzonitrile, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HBC
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13229 | | Descriptor: | 2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HBO
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13368 | | Descriptor: | Heat shock protein HSP 90-alpha, N-[(1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-yl]-N'-butyl-N-methylurea | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HC0
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 4W-0801 | | Descriptor: | 3-(3-bromothiophen-2-yl)-1H-pyrazole, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAV
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12879 | | Descriptor: | 3-amino-5-tert-butylthiophene-2-carboxamide, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HB2
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with FL0184 | | Descriptor: | 2-methoxy-7,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HAT
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12860 | | Descriptor: | (furan-2-yl)(thiomorpholin-4-yl)methanone, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HB9
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13464 | | Descriptor: | 2,5-dichlorothiophene-3-sulfonamide, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HBG
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13237 | | Descriptor: | Heat shock protein HSP 90-alpha, N-methyl-1-{4-[(pyridin-2-yl)oxy]phenyl}methanamine | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HBD
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12810 | | Descriptor: | Heat shock protein HSP 90-alpha, N-(3-chlorophenyl)-2-cyanoacetamide | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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7HBB
 | | PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13430 | | Descriptor: | 3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide, Heat shock protein HSP 90-alpha | | Authors: | Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. | | Deposit date: | 2024-07-10 | | Release date: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening.
Iucrj, 12, 2025
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