7ZC8
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1NLM
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![BU of 1nlm by Molmil](/molmil-images/mine/1nlm) | CRYSTAL STRUCTURE OF MURG:GLCNAC COMPLEX | Descriptor: | GLYCEROL, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Hu, Y, Chen, L, Ha, S, Gross, B, Falcone, B, Walker, D, Mokhtarzadeh, M, Walker, S. | Deposit date: | 2003-01-07 | Release date: | 2003-02-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases Proc.Natl.Acad.Sci.USA, 100, 2003
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8V2F
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![BU of 8v2f by Molmil](/molmil-images/mine/8v2f) | Crystal structure of IRAK4 kinase domain with compound 9 | Descriptor: | CHLORIDE ION, GLYCEROL, Interleukin-1 receptor-associated kinase 4, ... | Authors: | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | Deposit date: | 2023-11-22 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma. J.Med.Chem., 67, 2024
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8V1O
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![BU of 8v1o by Molmil](/molmil-images/mine/8v1o) | Crystal structure of IRAK4 kinase domain with compound 4 | Descriptor: | CHLORIDE ION, GLYCEROL, Interleukin-1 receptor-associated kinase 4, ... | Authors: | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | Deposit date: | 2023-11-21 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma. J.Med.Chem., 67, 2024
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8V2L
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![BU of 8v2l by Molmil](/molmil-images/mine/8v2l) | Crystal structure of IRAK4 kinase domain with compound 8 | Descriptor: | 1,2-ETHANEDIOL, Interleukin-1 receptor-associated kinase 4, N-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | Authors: | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | Deposit date: | 2023-11-22 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma. J.Med.Chem., 67, 2024
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1F0K
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![BU of 1f0k by Molmil](/molmil-images/mine/1f0k) | THE 1.9 ANGSTROM CRYSTAL STRUCTURE OF E. COLI MURG | Descriptor: | SULFATE ION, UDP-N-ACETYLGLUCOSAMINE-N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE | Authors: | Ha, S, Walker, D, Shi, Y, Walker, S. | Deposit date: | 2000-05-16 | Release date: | 2000-07-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The 1.9 A crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis. Protein Sci., 9, 2000
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4FZL
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![BU of 4fzl by Molmil](/molmil-images/mine/4fzl) | High resolution structure of truncated bacteriocin syringacin M from Pseudomonas syringae pv. tomato DC3000 | Descriptor: | 1,2-ETHANEDIOL, Bacteriocin, CALCIUM ION, ... | Authors: | Roszak, A.W, Grinter, R, Cogdell, J.R, Walker, D. | Deposit date: | 2012-07-06 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | The Crystal Structure of the Lipid II-degrading Bacteriocin Syringacin M Suggests Unexpected Evolutionary Relationships between Colicin M-like Bacteriocins. J.Biol.Chem., 287, 2012
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4FZN
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4FZM
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![BU of 4fzm by Molmil](/molmil-images/mine/4fzm) | Crystal structure of the bacteriocin syringacin M from Pseudomonas syringae pv. tomato DC3000 | Descriptor: | 1,2-ETHANEDIOL, Bacteriocin, CALCIUM ION | Authors: | Roszak, A.W, Grinter, R, Cogdell, J.R, Walker, D. | Deposit date: | 2012-07-06 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | The Crystal Structure of the Lipid II-degrading Bacteriocin Syringacin M Suggests Unexpected Evolutionary Relationships between Colicin M-like Bacteriocins. J.Biol.Chem., 287, 2012
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4ZHP
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![BU of 4zhp by Molmil](/molmil-images/mine/4zhp) | The crystal structure of Potato ferredoxin I with 2Fe-2S cluster | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, Potato Ferredoxin I | Authors: | Grinter, R, Josts, I, Roszak, A.W, Cogdell, R.J, Walker, D. | Deposit date: | 2015-04-26 | Release date: | 2016-08-31 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Structure of the bacterial plant-ferredoxin receptor FusA. Nat Commun, 7, 2016
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4ZGV
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![BU of 4zgv by Molmil](/molmil-images/mine/4zgv) | The Crystal Structure of the Ferredoxin Receptor FusA from Pectobacterium atrosepticum SCRI1043 | Descriptor: | Ferredoxin receptor, LAURYL DIMETHYLAMINE-N-OXIDE, octyl beta-D-glucopyranoside | Authors: | Grinter, R, Josts, I, Roszak, A.W, Cogdell, R.J, Walker, D. | Deposit date: | 2015-04-24 | Release date: | 2016-08-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of the bacterial plant-ferredoxin receptor FusA. Nat Commun, 7, 2016
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4ZHO
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![BU of 4zho by Molmil](/molmil-images/mine/4zho) | The crystal structure of Arabidopsis ferredoxin 2 with 2Fe-2S cluster | Descriptor: | CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-2, ... | Authors: | Grinter, R, Josts, I, Roszak, A.W, Cogdell, R.J, Walker, D. | Deposit date: | 2015-04-26 | Release date: | 2016-08-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure of the bacterial plant-ferredoxin receptor FusA. Nat Commun, 7, 2016
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1E44
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![BU of 1e44 by Molmil](/molmil-images/mine/1e44) | ribonuclease domain of colicin E3 in complex with its immunity protein | Descriptor: | 1,2-ETHANEDIOL, COLICIN E3, IMMUNITY PROTEIN | Authors: | Carr, S, Walker, D, James, R, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2000-06-28 | Release date: | 2001-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibition of a Ribosome Inactivating Ribonuclease: The Crystal Structure of the Cytotoxic Domain of Colicin E3 in Complex with its Immunity Protein Structure, 8, 2000
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2IVZ
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![BU of 2ivz by Molmil](/molmil-images/mine/2ivz) | Structure of TolB in complex with a peptide of the colicin E9 T- domain | Descriptor: | CALCIUM ION, COLICIN-E9, PROTEIN TOLB | Authors: | Loftus, S.R, Walker, D, Mate, M.J, Bonsor, D.A, James, R, Moore, G.R, Kleanthous, C. | Deposit date: | 2006-06-23 | Release date: | 2006-08-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Competitive Recruitment of the Periplasmic Translocation Portal Tolb by a Natively Disordered Domain of Colicin E9 Proc.Natl.Acad.Sci.USA, 103, 2006
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4QKO
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![BU of 4qko by Molmil](/molmil-images/mine/4qko) | The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms | Descriptor: | BROMIDE ION, MAGNESIUM ION, Pyocin-S2, ... | Authors: | Grinter, R, Josts, I, Roszak, A.W, Cogdell, C.J, Walker, D. | Deposit date: | 2014-06-07 | Release date: | 2015-06-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Insights into pyocin S2 To be Published
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4QAY
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4RTD
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![BU of 4rtd by Molmil](/molmil-images/mine/4rtd) | Escherichia coli alpha-2-macroglobulin activated by porcine elastase | Descriptor: | Uncharacterized lipoprotein YfhM | Authors: | Fyfe, C.D, Grinter, R, Roszak, A.W, Josts, I, Cogdell, R.J, Walker, D. | Deposit date: | 2014-11-14 | Release date: | 2015-07-15 | Last modified: | 2015-07-29 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structure of protease-cleaved Escherichia coli alpha-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallogr.,Sect.D, 71, 2015
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4LEA
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![BU of 4lea by Molmil](/molmil-images/mine/4lea) | The Crystal Structure of Pyocin L1 bound to D-mannose at 2.55 Angstroms | Descriptor: | Pyocin L1, beta-D-mannopyranose | Authors: | Grinter, R, Roszak, A.W, Mccaughey, L, Cogdell, C.J, Walker, D. | Deposit date: | 2013-06-25 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor. Plos Pathog., 10, 2014
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4LE7
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![BU of 4le7 by Molmil](/molmil-images/mine/4le7) | The Crystal Structure of Pyocin L1 at 2.09 Angstroms | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Pyocin L1 | Authors: | Grinter, R, Roszak, A.W, Mccaughey, L, Cogdell, R.J, Walker, D. | Deposit date: | 2013-06-25 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor. Plos Pathog., 10, 2014
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4LED
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![BU of 4led by Molmil](/molmil-images/mine/4led) | The Crystal Structure of Pyocin L1 bound to D-rhamnose at 2.37 Angstroms | Descriptor: | Pyocin L1, alpha-D-rhamnopyranose | Authors: | Grinter, R, Roszak, A.W, Mccaughey, L, Cogdell, C.J, Walker, D. | Deposit date: | 2013-06-25 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor. Plos Pathog., 10, 2014
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4N58
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![BU of 4n58 by Molmil](/molmil-images/mine/4n58) | Crystal Structure of Pectocin M2 at 1.86 Angstroms | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Grinter, R, Roszak, A.W, Zeth, K, Cogdell, C.J, Walker, D. | Deposit date: | 2013-10-09 | Release date: | 2014-06-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure of the atypical bacteriocin pectocin M2 implies a novel mechanism of protein uptake. Mol.Microbiol., 93, 2014
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4N59
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![BU of 4n59 by Molmil](/molmil-images/mine/4n59) | The Crystal Structure of Pectocin M2 at 2.3 Angstroms | Descriptor: | CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, Pectocin M2, ... | Authors: | Zeth, K, Grinter, R, Roszak, A.W, Cogdell, R.J, Walker, D. | Deposit date: | 2013-10-09 | Release date: | 2014-06-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the atypical bacteriocin pectocin M2 implies a novel mechanism of protein uptake. Mol.Microbiol., 93, 2014
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5VTG
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6THK
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4UHP
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![BU of 4uhp by Molmil](/molmil-images/mine/4uhp) | Crystal structure of the pyocin AP41 DNase-Immunity complex | Descriptor: | BACTERIOCIN IMMUNITY PROTEIN, LARGE COMPONENT OF PYOCIN AP41 | Authors: | Joshi, A, Chen, S, Wojdyla, J.A, Kaminska, R, Kleanthous, C. | Deposit date: | 2015-03-25 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa J.Mol.Biol., 427, 2015
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