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14-3-3 sigma in complex with YAP pS127-peptide
Descriptor:	14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
Authors:	Schumacher, B, Skwarczynska, M, Rose, R, Ottmann, C.
Deposit date:	2010-04-08
Release date:	2010-09-15
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (1.15 Å)
Cite:	Structure of a 14-3-3[sigma]-YAP phosphopeptide complex at 1.15 A resolution Acta Crystallogr.,Sect.F, 66, 2010

Human 14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide and Cotylenin A
Descriptor:	(1R,3aS,4R,5R,6R,9aR,10E)-6-({(1S,2R,4S,5R,6R,8S,9S)-5-hydroxy-2-(methoxymethyl)-9-methyl-9-[(2S)-oxiran-2-yl]-3,7,10,1 1-tetraoxatricyclo[6.2.1.0~1,6~]undec-4-yl}oxy)-1-(methoxymethyl)-4,9a-dimethyl-7-(propan-2-yl)-1,2,3,3a,4,5,6,8,9,9a-de cahydrodicyclopenta[a,d][8]annulene-1,5-diol, 14-3-3 protein zeta/delta, POTASSIUM ION, ...
Authors:	Molzan, M, Ottmann, C.
Deposit date:	2012-12-19
Release date:	2013-09-25
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers. Acs Chem.Biol., 8, 2013

14-3-3 isoform sigma in complex with a phosphorylated C-RAF peptide
Descriptor:	14-3-3 protein sigma, RAF proto-oncogene serine/threonine-protein kinase
Authors:	Molzan, M, Ottmann, C.
Deposit date:	2012-12-13
Release date:	2013-09-25
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers. Acs Chem.Biol., 8, 2013