7DSU
| Structure of Mod subunit of the Type III restriction-modification enzyme Mbo45V | Descriptor: | 1,2-ETHANEDIOL, Mbo45V, SINEFUNGIN | Authors: | Ahmed, I, Chouhan, O.P, Gopinath, A, Morgan, R.D, Bhagat, K, Singh, A, Saikrishnan, K. | Deposit date: | 2021-01-02 | Release date: | 2022-01-05 | Last modified: | 2023-04-05 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of Mod subunit of the Type III restriction-modification enzyme Mbo45V To Be Published
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7P9K
| BrxU, GmrSD-family Type IV restriction enzyme | Descriptor: | CHLORIDE ION, DUF262 domain-containing protein, GLYCEROL, ... | Authors: | Picton, D.M, Luyten, Y, Morgan, R.D, Nelson, A, Smith, D.L, Dryden, D.T.F, Hinton, J.C.D, Blower, T.R. | Deposit date: | 2021-07-27 | Release date: | 2021-12-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses. Nucleic Acids Res., 49, 2021
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7P9M
| BrxU, GmrSD-family Type IV restriction enzyme | Descriptor: | CHLORIDE ION, DUF262 domain-containing protein, SULFATE ION | Authors: | Picton, D.M, Luyten, Y, Morgan, R.D, Nelson, A, Smith, D.L, Dryden, D.T.F, Hinton, J.C.D, Blower, T.R. | Deposit date: | 2021-07-27 | Release date: | 2021-12-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses. Nucleic Acids Res., 49, 2021
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5HR4
| Structure of Type IIL restriction-modification enzyme MmeI in complex with DNA has implications for engineering of new specificities | Descriptor: | CALCIUM ION, DNA (5'-D(P*GP*TP*TP*AP*TP*GP*TP*CP*GP*GP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*CP*CP*GP*AP*CP*AP*TP*AP*AP*C)-3'), ... | Authors: | Callahan, S.J, Luyten, Y.A, Gupta, Y.K, Wilson, G.G, Roberts, R.J, Morgan, R.D, Aggarwal, A.K. | Deposit date: | 2016-01-22 | Release date: | 2016-04-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.5964 Å) | Cite: | Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities. Plos Biol., 14, 2016
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3LDY
| An extraordinary mechanism of DNA perturbation exhibited by the rare-cutting HNH restriction endonuclease PacI | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*AP*GP*GP*CP*TP*TP*A)-3'), DNA (5'-D(P*AP*TP*TP*AP*AP*GP*CP*CP*TP*C)-3'), ... | Authors: | Shen, B.W, Heiter, D, Chan, S.-H, Xu, S.-Y, Wilson, G, Stoddard, B.L. | Deposit date: | 2010-01-13 | Release date: | 2010-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI. Structure, 18, 2010
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3M7K
| Crystal structure of PacI-DNA Enzyme product complex | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*TP*TP*AP*AP*T)-3'), DNA (5'-D(P*TP*AP*AP*GP*CP*CP*TP*C)-3'), ... | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2010-03-16 | Release date: | 2010-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI. Structure, 18, 2010
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7QFZ
| BrxR, a WYL-domain containing transcriptional regulator | Descriptor: | SULFATE ION, WYL domain-containing protein | Authors: | Picton, D.M, Blower, T.R. | Deposit date: | 2021-12-07 | Release date: | 2022-05-18 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A widespread family of WYL-domain transcriptional regulators co-localizes with diverse phage defence systems and islands. Nucleic Acids Res., 50, 2022
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8EMC
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8EMH
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8EIL
| C-Terminal Domain of BrxL from Acinetobacter BREX type I phage restriction system | Descriptor: | MALONIC ACID, Protease Lon-related BREX system protein BrxL, SUCCINIC ACID | Authors: | Doyle, L.A, Stoddard, B.L, Kaiser, B. | Deposit date: | 2022-09-15 | Release date: | 2023-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor. Nucleic Acids Res., 51, 2023
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8EM1
| Type IIS Restriction Endonuclease PaqCI, DNA Unbound | Descriptor: | 1,2-ETHANEDIOL, PaqCI, DNA Unbound | Authors: | Kennedy, M.A, Stoddard, B.L. | Deposit date: | 2022-09-26 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI. Nucleic Acids Res., 51, 2023
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8EPX
| Type IIS Restriction Endonuclease PaqCI, DNA bound | Descriptor: | CALCIUM ION, DNA 1a, DNA 1b, ... | Authors: | Kennedy, M.A, Stoddard, B.L. | Deposit date: | 2022-10-06 | Release date: | 2023-03-22 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI. Nucleic Acids Res., 51, 2023
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7T8L
| BrxR from Acinetobacter BREX type I phage restriction system | Descriptor: | 1,2-ETHANEDIOL, BrxR, CHLORIDE ION | Authors: | Doyle, L, Kaiser, B, Stoddard, B. | Deposit date: | 2021-12-16 | Release date: | 2022-05-18 | Last modified: | 2022-06-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Res., 50, 2022
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7T8K
| BrxR from Acinetobacter BREX type I phage restriction system bound to DNA | Descriptor: | 1,2-ETHANEDIOL, BrxR, CHLORIDE ION, ... | Authors: | Doyle, L, Kaiser, B, Stoddard, B. | Deposit date: | 2021-12-16 | Release date: | 2022-05-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Res., 50, 2022
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8C45
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8Q56
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7LO5
| cryoEM structure DrdV-DNA complex | Descriptor: | CALCIUM ION, DNA (27-MER), DNA (28-MER), ... | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2021-02-09 | Release date: | 2021-03-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM. Structure, 29, 2021
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7LVV
| cryoEM structure DrdV-DNA complex | Descriptor: | CALCIUM ION, DNA (27-MER), DNA (28-MER), ... | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2021-02-26 | Release date: | 2021-03-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM. Structure, 29, 2021
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