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5MU8
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HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525
Descriptor: Tumor necrosis factor, ~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine
Authors:Blevitt, J.M, Hack, M.D, Herman, K.L, Jackson, P.F, Krawczuk, P.J, Lebsack, A.D, Liu, A.X, Mirzadegan, T, Nelen, M.I, Patrick, A.P, Steinbacher, S, Milla, M.E, Lumb, K.J.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.
J. Med. Chem., 60, 2017

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