6ILQ
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![BU of 6ilq by Molmil](/molmil-images/mine/6ilq) | Crystal structure of PPARgamma with compound BR101549 | Descriptor: | Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma, ethyl [2-butyl-6-oxo-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}-4-(propan-2-yl)-1,6-dihydropyrimidin-5-yl]acetate | Authors: | Hong, E, Jang, T.H, Chin, J, Kim, K.H, Jung, W, Kim, S.H. | Deposit date: | 2018-10-19 | Release date: | 2019-09-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.408 Å) | Cite: | Identification of BR101549 as a lead candidate of non-TZD PPAR gamma agonist for the treatment of type 2 diabetes: Proof-of-concept evaluation and SAR. Bioorg.Med.Chem.Lett., 29, 2019
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7XL9
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![BU of 7xl9 by Molmil](/molmil-images/mine/7xl9) | The structure of HucR with urate | Descriptor: | CHLORIDE ION, Transcriptional regulator, MarR family, ... | Authors: | Park, S.Y. | Deposit date: | 2022-04-21 | Release date: | 2022-07-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | The structure of Deinococcus radiodurans transcriptional regulator HucR retold with the urate bound. Biochem.Biophys.Res.Commun., 615, 2022
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4QKV
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![BU of 4qkv by Molmil](/molmil-images/mine/4qkv) | |
4QKW
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![BU of 4qkw by Molmil](/molmil-images/mine/4qkw) | Crystal structure of the zebrafish cavin4a HR1 domain | Descriptor: | CHLORIDE ION, Muscle-related coiled-coil protein | Authors: | Kovtun, O, Tillu, V, Parton, R.G, Collins, B.M. | Deposit date: | 2014-06-10 | Release date: | 2015-03-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the organization of the cavin membrane coat complex Dev.Cell, 31, 2014
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6ICJ
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![BU of 6icj by Molmil](/molmil-images/mine/6icj) | Crystal structure of PPARgamma with compound BR102375K | Descriptor: | 2-butyl-5-[(3-tert-butyl-1,2,4-oxadiazol-5-yl)methyl]-6-methyl-3-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}pyrimidin-4(3H)-one, GLYCEROL, Nuclear receptor coactivator 1, ... | Authors: | Hong, E, Chin, J, Jang, T.H, Kim, K.H, Jung, W, Kim, S.H. | Deposit date: | 2018-09-06 | Release date: | 2019-09-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.483 Å) | Cite: | Crystal structure of PPARgamma with compound BR102375K To Be Published
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3V3C
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![BU of 3v3c by Molmil](/molmil-images/mine/3v3c) | |