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8IV3
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BU of 8iv3 by Molmil
Crystal structure of SARS-CoV2 N-NTD complexed with 5-Benzyloxygramine
Descriptor: N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine, Nucleoprotein
Authors:Hong, J.Y, Hou, M.H.
Deposit date:2023-03-25
Release date:2024-02-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Targeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2.
Biophys.J., 123, 2024
8J6X
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BU of 8j6x by Molmil
Crystal structure of SARS-CoV2 N-NTD complexed with 5-Benzyloxygramine derivative (P3-8)
Descriptor: Nucleoprotein, ~{N}-methyl-~{N}-[(5-phenylmethoxy-1~{H}-indol-3-yl)methyl]propan-1-amine
Authors:Hong, J.Y, Hou, M.H.
Deposit date:2023-04-26
Release date:2024-02-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Targeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2.
Biophys.J., 123, 2024
8IQJ
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BU of 8iqj by Molmil
Crystal structure of SARS-CoV2 N-NTD
Descriptor: Nucleoprotein
Authors:Hong, J.Y, Hou, M.H.
Deposit date:2023-03-16
Release date:2024-02-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Targeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2.
Biophys.J., 123, 2024
6NR0
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BU of 6nr0 by Molmil
SIRT2(56-356) with covalent intermediate between mechanism-based inhibitor Glucose-TM-1beta and 1'-SH ADP-ribose
Descriptor: GLYCEROL, NAD-dependent protein deacetylase sirtuin-2, N~2~-[3-(2-hydroxyethoxy)propanoyl]-N-phenyl-N~6~-tetradecanethioyl-L-lysinamide, ...
Authors:Price, I.R, Hong, J.
Deposit date:2019-01-22
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors.
Acs Chem.Biol., 14, 2019
7EAL
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BU of 7eal by Molmil
The structure of the A20-Binding Inhibitor of NF-kB 1 in complex with di-ubiquitin
Descriptor: GLYCEROL, TNFAIP3-interacting protein 1, ubiquitin
Authors:Lo, Y.C, Lin, S.C.
Deposit date:2021-03-07
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins.
J.Mol.Biol., 433, 2021
7EAO
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BU of 7eao by Molmil
The structure of the A20-binding inhibitor of NF-kB 1 in complex with tri-ubiquitin
Descriptor: Polyubiquitin-C, TNFAIP3-interacting protein 1
Authors:Lo, Y.C, Lin, S.C.
Deposit date:2021-03-07
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins.
J.Mol.Biol., 433, 2021
7EB9
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BU of 7eb9 by Molmil
The structure of the A20-binding inhibitor of NF-kB 1 in complex with tetra-ubiquitin
Descriptor: TNFAIP3-interacting protein 1, tetra ubiquitin
Authors:Lo, Y.C, Lin, S.C.
Deposit date:2021-03-09
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins.
J.Mol.Biol., 433, 2021
5X4F
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BU of 5x4f by Molmil
Solution Structure of the N-terminal Domain of TDP-43
Descriptor: TAR DNA-binding protein 43
Authors:Jiang, L.-L, Xue, W, Hu, H.-Y.
Deposit date:2017-02-13
Release date:2017-08-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The N-terminal dimerization is required for TDP-43 splicing activity.
Sci Rep, 7, 2017
5H07
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BU of 5h07 by Molmil
TNIP2-Ub complex, C2 form
Descriptor: Polyubiquitin-C, TNFAIP3-interacting protein 2
Authors:Lo, Y.C, Lin, S.C.
Deposit date:2016-10-04
Release date:2017-03-08
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:Structural Insights into Linear Tri-ubiquitin Recognition by A20-Binding Inhibitor of NF-kappa B, ABIN-2
Structure, 25, 2017
6LNN
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BU of 6lnn by Molmil
Crystal structure of MERS-CoV N-NTD complexed with ligand P4-1
Descriptor: 5-propoxy-1H-indole, Nucleoprotein
Authors:Hou, M.H, Lin, S.M, Hsu, J.N.
Deposit date:2019-12-31
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation.
Front Mol Biosci, 9, 2022
6K7W
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BU of 6k7w by Molmil
Solution Structure of the CS1 Domain of USP19
Descriptor: Ubiquitin carboxyl-terminal hydrolase 19
Authors:Xue, W, Hu, H.Y.
Deposit date:2019-06-10
Release date:2020-06-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
6KQV
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BU of 6kqv by Molmil
Solution Structure of the UbL Domain of USP19
Descriptor: Ubiquitin carboxyl-terminal hydrolase 19
Authors:Xue, W, Hu, H.Y.
Deposit date:2019-08-19
Release date:2020-08-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
6LZ6
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BU of 6lz6 by Molmil
Crystal structure of MERS-CoV N-NTD complexed with ligand P4-3
Descriptor: 5-(2-fluoranylethoxy)-1H-indole, Nucleoprotein
Authors:Hou, M.H, Lin, S.M, Hsu, J.N.
Deposit date:2020-02-18
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.646 Å)
Cite:Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation.
Front Mol Biosci, 9, 2022
6LZ8
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BU of 6lz8 by Molmil
Crystal structure of MERS-CoV N-NTD complexed with ligand P4-4
Descriptor: 5-(2-methoxyethoxy)-1H-indole, Nucleoprotein
Authors:Hou, M.H, Lin, S.M, Hsu, J.N.
Deposit date:2020-02-18
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation.
Front Mol Biosci, 9, 2022
6KHV
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BU of 6khv by Molmil
Solution Structure of the CS2 Domain of USP19
Descriptor: Ubiquitin carboxyl-terminal hydrolase 19
Authors:Xue, W, Hu, H.Y.
Deposit date:2019-07-16
Release date:2020-07-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
7DYD
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BU of 7dyd by Molmil
Crystal structure of MERS-CoV N-NTD complexed with ligand P4-2
Descriptor: 5-propan-2-yloxy-1H-indole, Nucleoprotein
Authors:Hou, M.H, Lin, S.M, Hsu, J.N.
Deposit date:2021-01-21
Release date:2022-01-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation.
Front Mol Biosci, 9, 2022
6F7A
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BU of 6f7a by Molmil
Gloeobacter Ligand-gated Ion Channel (GLIC) closed state crystallized in an ultra-swollen lipidic mesophase
Descriptor: Proton-gated ion channel
Authors:Martiel, I, Zabara, A, Chong, J.Y.T, Stark, L, Cromer, B, Dummond, C.J, Mezzenga, R.
Deposit date:2017-12-07
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (6 Å)
Cite:Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains.
Nat Commun, 9, 2018

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