8X3M
 
 | | Crystal structure of p38alpha with an allosteric inhibitor 2 | | Descriptor: | Mitogen-activated protein kinase 14, ~{N}-(5,6-dimethoxy-1,3-benzothiazol-2-yl)-2-[(4-fluoranylphenoxy)methyl]-1,3-thiazole-4-carboxamide | | Authors: | Hasegawa, S, Kinoshita, T. | | Deposit date: | 2023-11-14 | | Release date: | 2024-11-20 | | Last modified: | 2025-03-05 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Distinct binding modes of a benzothiazole derivative confer structural bases for increasing ERK2 or p38 alpha MAPK selectivity.
Biochem.Biophys.Res.Commun., 704, 2024
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8YD9
 | | Crystal structure of p38alpha with an allosteric inhibitor 3 | | Descriptor: | 13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine, GLYCEROL, Mitogen-activated protein kinase 14 | | Authors: | Hasegawa, S, Kinoshita, T. | | Deposit date: | 2024-02-19 | | Release date: | 2025-02-26 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Identification of a novel target site for ATP-independent p38 alpha inhibitors
To Be Published
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