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Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 56
Descriptor:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[(3~{R})-3-(cyclopropylmethylamino)piperidin-1-yl]-1-[(1~{R})-1-[4-[5-(dimethylamino)pyridin-3-yl]-1,2,3-triazol-1-yl]ethyl]pyridin-2-one, CALCIUM ION, ...
Authors:	Dutheuil, G, Oukoloff, K.
Deposit date:	2024-07-16
Release date:	2025-02-12
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 56 To Be Published

Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 59
Descriptor:	4-[(3~{R})-3-(cyclopropylmethylamino)piperidin-1-yl]-1-[(1~{R})-1-[4-(6-pyrrolidin-1-ylpyrazin-2-yl)-1,2,3-triazol-1-yl]ethyl]pyridin-2-one, CALCIUM ION, N6-adenosine-methyltransferase catalytic subunit, ...
Authors:	Dutheuil, G, Oukoloff, K.
Deposit date:	2024-07-16
Release date:	2025-02-12
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 59 To Be Published

Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 31
Descriptor:	4-[(3~{R})-3-(cyclobutylmethylamino)piperidin-1-yl]-1-[(1~{R})-1-[4-(5-methoxypyridin-3-yl)-1,2,3-triazol-1-yl]ethyl]pyridin-2-one, N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit
Authors:	Dutheuil, G, Oukoloff, K.
Deposit date:	2024-07-16
Release date:	2025-02-12
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 31 To Be Published