1BZ7
| FAB FRAGMENT FROM MURINE ASCITES | Descriptor: | PROTEIN (ANTIBODY R24 (HEAVY CHAIN)), PROTEIN (ANTIBODY R24 (LIGHT CHAIN)) | Authors: | Kaminski, M.J, Mackenzie, C.R, Mooibroek, M.J, Dahms, T.E.S, Hirama, T, Houghton, A.N, Chapman, P.B, Evans, S.V. | Deposit date: | 1998-11-06 | Release date: | 1999-11-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains. J.Biol.Chem., 274, 1999
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3OG7
| B-Raf Kinase V600E oncogenic mutant in complex with PLX4032 | Descriptor: | AKAP9-BRAF fusion protein, N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Authors: | Zhang, Y, Zhang, K.Y, Zhang, C. | Deposit date: | 2010-08-16 | Release date: | 2010-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature, 467, 2010
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1R24
| FAB FROM MURINE IGG3 KAPPA | Descriptor: | PROTEIN (IGG3-KAPPA ANTIBODY (HEAVY CHAIN)), PROTEIN (IGG3-KAPPA ANTIBODY (LIGHT CHAIN)) | Authors: | Evans, S.V. | Deposit date: | 1998-11-05 | Release date: | 1999-11-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains. J.Biol.Chem., 274, 1999
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