4GC2
 
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4GC1
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3ZBE
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4ELY
 | | CCDBVFI:GYRA14EC | | Descriptor: | CHLORIDE ION, CcdB, DNA gyrase subunit A, ... | | Authors: | De Jonge, N, Simic, R, Buts, L, Haesaerts, S, Roelants, K, Garcia-Pino, A, Sterckx, Y, De Greve, H, Lah, J, Loris, R. | | Deposit date: | 2012-04-11 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.932 Å) | | Cite: | Alternative interactions define gyrase specificity in the CcdB family.
Mol.Microbiol., 84, 2012
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8A0X
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8A0W
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5MI8
 | | Structure of the phosphomimetic mutant of EF-Tu T383E | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, BETA-MERCAPTOETHANOL, ... | | Authors: | Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A. | | Deposit date: | 2016-11-27 | | Release date: | 2017-12-20 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
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5MI9
 | | Structure of the phosphomimetic mutant of the elongation factor EF-Tu T62E | | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A. | | Deposit date: | 2016-11-27 | | Release date: | 2017-12-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
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5MI3
 | | Structure of phosphorylated translation elongation factor EF-Tu from E. coli | | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A. | | Deposit date: | 2016-11-27 | | Release date: | 2017-12-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
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5MJE
 | | Crystal structure of the HigB2 toxin in complex with Nb8 | | Descriptor: | Cytotoxic translational repressor of toxin-antitoxin stability system, DI(HYDROXYETHYL)ETHER, Nanobody 8, ... | | Authors: | Hadzi, S, Loris, R. | | Deposit date: | 2016-11-30 | | Release date: | 2017-04-05 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.599 Å) | | Cite: | Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
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4ELZ
 | | CCDBVFI:GYRA14VFI | | Descriptor: | CcdB, DNA gyrase subunit A, GLYCEROL | | Authors: | De Jonge, N, Simic, M, Buts, L, Haesaerts, S, Roelants, K, Garcia-Pino, A, Sterckx, Y, De Greve, H, Lah, J, Loris, R. | | Deposit date: | 2012-04-11 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Alternative interactions define gyrase specificity in the CcdB family.
Mol.Microbiol., 84, 2012
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5J9I
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5JA9
 | | Crystal structure of the HigB2 toxin in complex with Nb6 | | Descriptor: | 1,2-ETHANEDIOL, Nanobody 6, SULFATE ION, ... | | Authors: | Hadzi, S, Loris, R. | | Deposit date: | 2016-04-12 | | Release date: | 2017-04-05 | | Last modified: | 2017-05-17 | | Method: | X-RAY DIFFRACTION (1.849 Å) | | Cite: | Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
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5JAA
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5JA8
 | | Crystal structure of the HigB2 toxin in complex with Nb2 | | Descriptor: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Hadzi, S, Loris, R. | | Deposit date: | 2016-04-12 | | Release date: | 2017-04-05 | | Last modified: | 2019-02-20 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
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3JRZ
 | | CcdBVfi-FormII-pH5.6 | | Descriptor: | CcdB | | Authors: | De Jonge, N, Buts, L, Loris, R. | | Deposit date: | 2009-09-09 | | Release date: | 2009-12-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural and thermodynamic characterization of vibrio fischeri CCDB
J.Biol.Chem., 285, 2010
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1G7Y
 | | THE CRYSTAL STRUCTURE OF THE 58KD VEGETATIVE LECTIN FROM THE TROPICAL LEGUME DOLICHOS BIFLORUS | | Descriptor: | CALCIUM ION, MANGANESE (II) ION, STEM/LEAF LECTIN DB58, ... | | Authors: | Buts, L, Hamelryck, T.W, Loris, R, Dao-Thi, M.-H, Wyns, L, Etzler, M.E. | | Deposit date: | 2000-11-15 | | Release date: | 2000-11-29 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Weak protein-protein interactions in lectins: the crystal structure of a vegetative lectin from the legume Dolichos biflorus.
J.Mol.Biol., 309, 2001
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3JSC
 | | CcdBVfi-FormI-pH7.0 | | Descriptor: | CcdB, SULFATE ION | | Authors: | De Jonge, N, Buts, L, Loris, R. | | Deposit date: | 2009-09-10 | | Release date: | 2009-12-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and thermodynamic characterization of vibrio fischeri CCDB
J.Biol.Chem., 285, 2010
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4QO1
 | | p53 DNA binding domain in complex with Nb139 | | Descriptor: | Cellular tumor antigen p53, Nb139 Nanobody against the DNA-binding domain of p53, ZINC ION | | Authors: | De Gieter, S, Bethuyne, J, Gettemans, J, Garcia-Pino, A, Loris, R. | | Deposit date: | 2014-06-19 | | Release date: | 2014-10-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.924 Å) | | Cite: | A nanobody modulates the p53 transcriptional program without perturbing its functional architecture.
Nucleic Acids Res., 42, 2014
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4HOH
 | | RIBONUCLEASE T1 (THR93ALA MUTANT) COMPLEXED WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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6Y2P
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6Y2Q
 | | Escherichia coli RnlA endoribonuclease | | Descriptor: | CHLORIDE ION, mRNA endoribonuclease toxin LS | | Authors: | Garcia-Rodriguez, G, Loris, R. | | Deposit date: | 2020-02-17 | | Release date: | 2021-05-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Alternative dimerization is required for activity and inhibition of the HEPN ribonuclease RnlA.
Nucleic Acids Res., 49, 2021
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7AEX
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3M7H
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5DLO
 | | S. aureus MazF in complex with substrate analogue | | Descriptor: | CHLORIDE ION, DNA substrate analogue AUACAUA, Endoribonuclease MazF | | Authors: | Zorzini, V, Loris, R. | | Deposit date: | 2015-09-07 | | Release date: | 2016-09-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.401 Å) | | Cite: | Substrate recognition, regulation mechanism and activity regulation of MazF mRNA interferase.
To Be Published
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