Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3FP4
DownloadVisualize
BU of 3fp4 by Molmil
Crystal structure of Tom71 complexed with Ssa1 C-terminal fragment
Descriptor: CHLORIDE ION, SODIUM ION, SULFATE ION, ...
Authors:Li, J, Qian, X, Hu, J, Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3T0H
DownloadVisualize
BU of 3t0h by Molmil
Structure insights into mechanisms of ATP hydrolysis and the activation of human Hsp90
Descriptor: Heat shock protein HSP 90-alpha
Authors:Li, J.
Deposit date:2011-07-20
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90.
Acta Biochim Biophys Sin (Shanghai), 44, 2012
3T0Z
DownloadVisualize
BU of 3t0z by Molmil
Hsp90 N-terminal domain bound to ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-alpha, MAGNESIUM ION
Authors:Li, J.
Deposit date:2011-07-21
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.192 Å)
Cite:Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90.
Acta Biochim Biophys Sin (Shanghai), 44, 2012
3T10
DownloadVisualize
BU of 3t10 by Molmil
HSP90 N-terminal domain bound to ACP
Descriptor: Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Li, J.
Deposit date:2011-07-21
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90.
Acta Biochim Biophys Sin (Shanghai), 44, 2012
7WJS
DownloadVisualize
BU of 7wjs by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y13157
Descriptor: 2-(2-cyclobutyl-1~{H}-imidazol-5-yl)-7-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-5-methyl-furo[3,2-c]pyridin-4-one, Bromodomain-containing protein 4, GLYCEROL
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-07
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
7WKY
DownloadVisualize
BU of 7wky by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y13153
Descriptor: 2-(2-cyclopentyl-1~{H}-imidazol-5-yl)-7-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-5-methyl-furo[3,2-c]pyridin-4-one, Bromodomain-containing protein 4, GLYCEROL
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-12
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
7WNI
DownloadVisualize
BU of 7wni by Molmil
Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13158
Descriptor: 1,2-ETHANEDIOL, 7-[2-[2,4-bis(fluoranyl)phenoxy]-5-(2-oxidanylpropan-2-yl)phenyl]-2-[4-(2-hydroxyethyloxy)-3,5-dimethyl-phenyl]-5-methyl-furo[3,2-c]pyridin-4-one, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-18
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
7WMU
DownloadVisualize
BU of 7wmu by Molmil
Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13146
Descriptor: 1,2-ETHANEDIOL, Isoform 4 of Bromodomain-containing protein 2, ~{N}-[4-[2,4-bis(fluoranyl)phenoxy]-3-[2-(2-cyclobutyl-1~{H}-imidazol-5-yl)-5-methyl-4-oxidanylidene-furo[3,2-c]pyridin-7-yl]phenyl]ethanesulfonamide
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-17
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
7WN5
DownloadVisualize
BU of 7wn5 by Molmil
Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13142
Descriptor: 1,2-ETHANEDIOL, Isoform 4 of Bromodomain-containing protein 2, POTASSIUM ION, ...
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-17
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
7WLN
DownloadVisualize
BU of 7wln by Molmil
Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13153
Descriptor: 2-(2-cyclopentyl-1~{H}-imidazol-5-yl)-7-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-5-methyl-furo[3,2-c]pyridin-4-one, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-13
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
7WNA
DownloadVisualize
BU of 7wna by Molmil
Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13120
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Isoform 4 of Bromodomain-containing protein 2, ...
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-17
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
7WMQ
DownloadVisualize
BU of 7wmq by Molmil
Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13157
Descriptor: 2-(2-cyclobutyl-1~{H}-imidazol-5-yl)-7-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-5-methyl-furo[3,2-c]pyridin-4-one, FORMIC ACID, GLYCEROL, ...
Authors:Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-01-16
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.
J.Med.Chem., 65, 2022
1C8U
DownloadVisualize
BU of 1c8u by Molmil
CRYSTAL STRUCTURE OF THE E.COLI THIOESTERASE II, A HOMOLOGUE OF THE HUMAN NEF-BINDING ENZYME
Descriptor: ACYL-COA THIOESTERASE II, LAURYL DIMETHYLAMINE-N-OXIDE
Authors:Li, J, Derewenda, Z.S.
Deposit date:1999-07-29
Release date:2000-07-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the Escherichia coli thioesterase II, a homolog of the human Nef binding enzyme.
Nat.Struct.Biol., 7, 2000
8WY4
DownloadVisualize
BU of 8wy4 by Molmil
GajA tetramer with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-10-30
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X5I
DownloadVisualize
BU of 8x5i by Molmil
tetramer Gabija with ATP (local refinement)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, MAGNESIUM ION
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-11-17
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X5N
DownloadVisualize
BU of 8x5n by Molmil
Tetramer Gabija with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ...
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-11-17
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X51
DownloadVisualize
BU of 8x51 by Molmil
Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement)
Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ...
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-11-16
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
3RY7
DownloadVisualize
BU of 3ry7 by Molmil
Crystal Structure of Sa239
Descriptor: GLYCEROL, Ribokinase
Authors:Li, J, Wu, M, Wang, L, Zang, J.
Deposit date:2011-05-11
Release date:2012-04-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of Sa239 reveals the structural basis for the activation of ribokinase by monovalent cations.
J.Struct.Biol., 177, 2012
6CYZ
DownloadVisualize
BU of 6cyz by Molmil
Mycobacterial homoserine kinase ThrB in complex with AMPPNP
Descriptor: CHLORIDE ION, Homoserine kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Li, J, Korotkov, K.V.
Deposit date:2018-04-07
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Mycobacterial homoserine kinase ThrB
To Be Published
4O7P
DownloadVisualize
BU of 4o7p by Molmil
Crystal structure of Mycobacterium tuberculosis maltose kinase MaK complexed with maltose
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Maltokinase, SULFATE ION, ...
Authors:Li, J, Guan, X.T, Rao, Z.H.
Deposit date:2013-12-26
Release date:2014-10-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Homotypic dimerization of a maltose kinase for molecular scaffolding.
Sci Rep, 4, 2014
4O7O
DownloadVisualize
BU of 4o7o by Molmil
Crystal structure of Mycobacterium tuberculosis maltose kinase MaK
Descriptor: Maltokinase, SULFATE ION
Authors:Li, J, Guan, X.T, Rao, Z.H.
Deposit date:2013-12-26
Release date:2014-10-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4006 Å)
Cite:Homotypic dimerization of a maltose kinase for molecular scaffolding.
Sci Rep, 4, 2014
8EW5
DownloadVisualize
BU of 8ew5 by Molmil
The structure of flightin within myosin thick filaments from Bombus ignitus flight muscle
Descriptor: Flightin
Authors:Li, J, Rahmani, H, Abbasi Yeganeh, F, Rastegarpouyani, H, Taylor, D.W, Wood, N.B, Previs, M.J, Iwamoto, H, Taylor, K.A.
Deposit date:2022-10-21
Release date:2023-01-04
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of the Flight Muscle Thick Filament from the Bumble Bee, Bombus ignitus , at 6 angstrom Resolution.
Int J Mol Sci, 24, 2022
7WNT
DownloadVisualize
BU of 7wnt by Molmil
RNase J from Mycobacterium tuberculosis
Descriptor: Ribonuclease J, ZINC ION
Authors:Li, J, Bao, L, Hu, J, Zhan, B, Li, Z.
Deposit date:2022-01-19
Release date:2023-01-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural ans functional study of RNase J from Mycobacterium tuberculosis
To Be Published
7WNU
DownloadVisualize
BU of 7wnu by Molmil
Mycobacterium tuberculosis Rnase J complex with 7nt RNA
Descriptor: RNA (5'-R(P*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease J, ZINC ION
Authors:Li, J, Hu, J, Bao, L, Zhan, B, Li, Z.
Deposit date:2022-01-19
Release date:2023-01-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural ans functional study of RNase J from Mycobacterium tuberculosis
To Be Published
2AD6
DownloadVisualize
BU of 2ad6 by Molmil
crystal structure of methanol dehydrogenase from M. W3A1 (form C)
Descriptor: CALCIUM ION, Methanol dehydrogenase subunit 1, Methanol dehydrogenase subunit 2, ...
Authors:Li, J, Gan, J.-H, Xia, Z.-X, Mathews, F.S.
Deposit date:2005-07-20
Release date:2006-07-25
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The enzymatic reaction-induced configuration change of the prosthetic group PQQ of methanol dehydrogenase
Biochem.Biophys.Res.Commun., 406, 2011

221716

건을2024-06-26부터공개중

PDB statisticsPDBj update infoContact PDBjnumon