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Crystal structure of human caspase-1 with a naturally-occurring Arg240->Gln substitution in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor:	Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:	Rosen-Wolff, A, Roesler, J, Romanowski, M.J.
Deposit date:	2008-05-19
Release date:	2010-03-02
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Mutated, structurally altered caspase-1 with decreased enzymatic and increased RIP2-meditated inflammatory activity leads to a new type of periodic fever (ICE fever). To be Published

Crystal structure of human caspase-1 with a naturally-occurring Asn263->Ser substitution in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor:	Caspase-1, Caspase-1 precursor, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:	Rosen-Wolff, A, Roesler, J, Romanowski, M.J.
Deposit date:	2008-05-19
Release date:	2010-03-02
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Mutated, structurally altered caspase-1 with decreased enzymatic and increased RIP2-meditated inflammatory activity leads to a new type of periodic fever (ICE fever). To be Published, 2008

GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM
Descriptor:	GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR
Authors:	Schalk, I, Zeng, K, Wu, S.-K, Stura, E.A, Metteson, J, Huang, M, Tandon, A, Wilson, I.A, Balch, W.E.
Deposit date:	1996-07-10
Release date:	1997-02-12
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.81 Å)
Cite:	Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature, 381, 1996

3-DEHYDROQUINATE DEHYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH SULPHATE
Descriptor:	3-DEHYDROQUINATE DEHYDRATASE, SULFATE ION
Authors:	Roszak, A.W, Coggins, J.R, Lapthorn, A.J.
Deposit date:	2002-06-11
Release date:	2002-10-24
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Specificity of Substrate Recognition by Type II Dehydroquinases as Revealed by Binding of Polyanions(1) FEBS Lett., 530, 2002