6D0J
| Crystal structure of a CLC-type fluoride/proton antiporter | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | Authors: | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | Deposit date: | 2018-04-10 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
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7P0K
| Crystal structure of Autotaxin (ENPP2) with 18F-labeled positron emission tomography ligand | Descriptor: | 2-[[2-ethyl-6-[4-[2-[(3~{R})-3-fluoranylpyrrolidin-1-yl]-2-oxidanylidene-ethyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]-methyl-amino]-4-(4-fluorophenyl)-2,3-dihydro-1,3-thiazole-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Salgado-Polo, F, Shao, T, Xiao, Z, Van, R, Chen, J, Rong, J, Haider, A, Shao, Y, Josephson, L, Perrakis, A, Liang, S.H. | Deposit date: | 2021-06-29 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Imaging Autotaxin In Vivo with 18 F-Labeled Positron Emission Tomography Ligands J Med Chem, 64, 2021
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3AH2
| HA1 subcomponent of botulinum type C progenitor toxin complexed with N-acetylgalactosamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, Main hemagglutinin component | Authors: | Nakamura, T, Tonozuka, T, Ide, A, Yuzawa, T, Oguma, K, Nishikawa, A. | Deposit date: | 2010-04-13 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Sugar-binding sites of the HA1 subcomponent of Clostridium botulinum type C progenitor toxin J.Mol.Biol., 376, 2008
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3AH1
| HA1 subcomponent of botulinum type C progenitor toxin complexed with N-acetylneuramic acid | Descriptor: | Main hemagglutinin component, N-acetyl-beta-neuraminic acid | Authors: | Nakamura, T, Tonozuka, T, Ide, A, Yuzawa, T, Oguma, K, Nishikawa, A. | Deposit date: | 2010-04-13 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Sugar-binding sites of the HA1 subcomponent of Clostridium botulinum type C progenitor toxin J.Mol.Biol., 376, 2008
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2ZOE
| HA3 subcomponent of Clostridium botulinum type C progenitor toxin, complex with N-acetylneuramic acid | Descriptor: | Hemagglutinin components HA3, N-acetyl-beta-neuraminic acid | Authors: | Nakamura, T, Kotani, M, Tonozuka, T, Ide, A, Oguma, K, Nishikawa, A. | Deposit date: | 2008-05-09 | Release date: | 2008-12-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the HA3 Subcomponent of Clostridium botulinum Type C Progenitor Toxin J.Mol.Biol., 385, 2009
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3AH4
| HA1 subcomponent of botulinum type C progenitor toxin complexed with galactose | Descriptor: | Main hemagglutinin component, beta-D-galactopyranose | Authors: | Nakamura, T, Tonozuka, T, Ide, A, Yuzawa, T, Oguma, K, Nishikawa, A. | Deposit date: | 2010-04-13 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Sugar-binding sites of the HA1 subcomponent of Clostridium botulinum type C progenitor toxin J.Mol.Biol., 376, 2008
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7LO7
| NorA in complex with Fab25 | Descriptor: | Fab25 Heavy Chain, Fab25 Light Chain, Quinolone resistance protein NorA | Authors: | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | Deposit date: | 2021-02-09 | Release date: | 2022-04-20 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus. Nat.Chem.Biol., 18, 2022
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7LO8
| NorA in complex with Fab36 | Descriptor: | Fab36 Heavy Chain, Fab36 Light Chain, Quinolone resistance protein NorA | Authors: | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | Deposit date: | 2021-02-09 | Release date: | 2022-04-20 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus. Nat.Chem.Biol., 18, 2022
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8TTH
| NorA single mutant - D307N at pH 7.5 | Descriptor: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | Authors: | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | Deposit date: | 2023-08-13 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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8TTG
| NorA single mutant - E222Q at pH 7.5 | Descriptor: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | Authors: | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | Deposit date: | 2023-08-13 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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8TTF
| NorA double mutant - E222QD307N at pH 7.5 | Descriptor: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | Authors: | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | Deposit date: | 2023-08-13 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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8TTE
| Protonated state of NorA at pH 5.0 | Descriptor: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | Authors: | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | Deposit date: | 2023-08-13 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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7QE0
| 80S-bound human SKI complex in the open state | Descriptor: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-12-01 | Release date: | 2022-02-09 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDZ
| 80S-bound human SKI complex in the closed state | Descriptor: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-12-01 | Release date: | 2022-02-09 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDS
| Apo human SKI complex in the open state | Descriptor: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | Authors: | Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. | Deposit date: | 2021-11-30 | Release date: | 2022-02-02 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDR
| Apo human SKI complex in the closed state | Descriptor: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-11-29 | Release date: | 2022-02-02 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDY
| RNA-bound human SKI complex | Descriptor: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-12-01 | Release date: | 2022-02-09 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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6WW5
| Structure of VcINDY-Na-Fab84 in nanodisc | Descriptor: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, DASS family sodium-coupled anion symporter, Fab84 Heavy Chain, ... | Authors: | Sauer, D.B, Marden, J, Song, J.M, Koide, A, Koide, S, Wang, D.N. | Deposit date: | 2020-05-07 | Release date: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters. Elife, 9, 2020
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6HIY
| Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the body of the small mitoribosomal subunit in complex with mt-IF-3 | Descriptor: | 9S rRNA, MAGNESIUM ION, SPERMIDINE, ... | Authors: | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | Deposit date: | 2018-08-31 | Release date: | 2018-09-26 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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6HIX
| Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit | Descriptor: | 12S rRNA, 50S ribosomal protein L13, putative, ... | Authors: | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | Deposit date: | 2018-08-31 | Release date: | 2018-09-26 | Last modified: | 2019-02-06 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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6HIW
| Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete small mitoribosomal subunit in complex with mt-IF-3 | Descriptor: | 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ramrath, D, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | Deposit date: | 2018-08-31 | Release date: | 2018-09-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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6HIZ
| Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the head of the small mitoribosomal subunit | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (143-MER), ... | Authors: | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, A, Schneider, A, Ban, N. | Deposit date: | 2018-08-31 | Release date: | 2018-09-26 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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7YA8
| The crystal structure of IpaH2.5 LRR domain | Descriptor: | RING-type E3 ubiquitin transferase | Authors: | Hiragi, K, Nishide, A, Takagi, K, Iwai, K, Kim, M, Mizushima, T. | Deposit date: | 2022-06-27 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural insight into the recognition of the linear ubiquitin assembly complex by Shigella E3 ligase IpaH1.4/2.5. J.Biochem., 173, 2023
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7YA7
| The crystal structure of IpaH1.4 LRR domain | Descriptor: | RING-type E3 ubiquitin transferase | Authors: | Hiragi, K, Nishide, A, Takagi, K, Iwai, K, Kim, M, Mizushima, T. | Deposit date: | 2022-06-27 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insight into the recognition of the linear ubiquitin assembly complex by Shigella E3 ligase IpaH1.4/2.5. J.Biochem., 173, 2023
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6HIV
| Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete mitoribosome | Descriptor: | 12S rRNA, 50S ribosomal protein L13, putative, ... | Authors: | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boerhringer, D, Schneider, A, Ban, N. | Deposit date: | 2018-08-31 | Release date: | 2018-10-03 | Last modified: | 2018-11-07 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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