7N60
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![BU of 7n60 by Molmil](/molmil-images/mine/7n60) | The crystal structure of 4-methoxybenzoate-bound CYP199A S244D mutant | Descriptor: | 4-METHOXYBENZOIC ACID, CHLORIDE ION, Cytochrome P450, ... | Authors: | Lau, I.C.K, Coleman, T, Bell, S.G, Bruning, J.B. | Deposit date: | 2021-06-07 | Release date: | 2022-06-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | The crystal structure of 4-methoxybenzoate-bound CYP199A S244D mutant To Be Published
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8G36
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![BU of 8g36 by Molmil](/molmil-images/mine/8g36) | Crystal structure of F182L-CYP199A4 in complex with terephthalic acid | Descriptor: | CHLORIDE ION, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Lee, J.H.Z, Bruning, J.B, Bell, S.G. | Deposit date: | 2023-02-06 | Release date: | 2023-05-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme. J.Am.Chem.Soc., 145, 2023
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8G35
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![BU of 8g35 by Molmil](/molmil-images/mine/8g35) | Crystal structure of F182L-CYP199A4 in complex with (S)-4-(2-hydroxy-3-oxobutan-2-yl)benzoic acid | Descriptor: | 4-[(2S)-2-hydroxy-3-oxobutan-2-yl]benzoic acid, CHLORIDE ION, Cytochrome P450, ... | Authors: | Lee, J.H.Z, Bell, S.G, Bruning, J.B. | Deposit date: | 2023-02-06 | Release date: | 2023-05-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme. J.Am.Chem.Soc., 145, 2023
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8VF3
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![BU of 8vf3 by Molmil](/molmil-images/mine/8vf3) | |
8VF0
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![BU of 8vf0 by Molmil](/molmil-images/mine/8vf0) | |
8VFP
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![BU of 8vfp by Molmil](/molmil-images/mine/8vfp) | |
8VFR
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![BU of 8vfr by Molmil](/molmil-images/mine/8vfr) | |
8SWL
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![BU of 8swl by Molmil](/molmil-images/mine/8swl) | |
8TAY
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![BU of 8tay by Molmil](/molmil-images/mine/8tay) | |
8TAW
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![BU of 8taw by Molmil](/molmil-images/mine/8taw) | |
8TNK
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8FLO
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![BU of 8flo by Molmil](/molmil-images/mine/8flo) | X-ray crystal structure of substrate free CYP124A1 from Mycobacterium Marinum | Descriptor: | Cytochrome P450 124A1, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Ghith, A, Bruning, J.B, Bell, S.G. | Deposit date: | 2022-12-22 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 737, 2023
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8FJO
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![BU of 8fjo by Molmil](/molmil-images/mine/8fjo) | X-ray crystal structure of CYP124A1 from Mycobacterium Marinum in complex with farnesyl acetate | Descriptor: | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl acetate, AMMONIUM ION, Cytochrome P450 124A1, ... | Authors: | Ghith, A, Bruning, J.B, Bell, S.G. | Deposit date: | 2022-12-20 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 737, 2023
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8GDI
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![BU of 8gdi by Molmil](/molmil-images/mine/8gdi) | X-ray crystal structure of CYP124A1 from Mycobacterium Marinum in complex with 7-ketocholesterol | Descriptor: | (3beta,8alpha,9beta)-3-hydroxycholest-5-en-7-one, Cytochrome P450 124A1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ghith, A, Bruning, J.B, Bell, S.G. | Deposit date: | 2023-03-06 | Release date: | 2023-05-24 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum. J.Steroid Biochem.Mol.Biol., 231, 2023
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8FKB
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![BU of 8fkb by Molmil](/molmil-images/mine/8fkb) | X-ray crystal structure of CYP124A1 from Mycobacterium Marinum bound to Farnesol | Descriptor: | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, Cytochrome P450 124A1, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ghith, A, Bruning, J.B, Bell, S.G. | Deposit date: | 2022-12-21 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 737, 2023
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8GLZ
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![BU of 8glz by Molmil](/molmil-images/mine/8glz) | Crystal structure of T252E-CYP199A4 in complex with 4-hydroxybenzoic acid. Crystal was initially co-crystallised with 4-methoxybenzoic acid and soaked with 4 mM hydrogen peroxide | Descriptor: | CHLORIDE ION, Cytochrome P450, P-HYDROXYBENZOIC ACID, ... | Authors: | Lee, J.H.Z, Bruning, J.B, Bell, S.G. | Deposit date: | 2023-03-23 | Release date: | 2023-12-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase. Chemistry, 30, 2024
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8GM2
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![BU of 8gm2 by Molmil](/molmil-images/mine/8gm2) | |
8D39
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8D1C
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![BU of 8d1c by Molmil](/molmil-images/mine/8d1c) | Crystal structure of T252E-CYP199A4 in complex with 4-(Trifluoromethoxy)benzoic acid | Descriptor: | 4-(trifluoromethoxy)benzoic acid, CHLORIDE ION, Cytochrome P450, ... | Authors: | Lee, J.H.Z, Bruning, J.B, Bell, S.G. | Deposit date: | 2022-05-27 | Release date: | 2023-03-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Selective Oxidations Using a Cytochrome P450 Enzyme Variant Driven with Surrogate Oxygen Donors and Light. Chemistry, 28, 2022
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8DYB
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8E5J
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![BU of 8e5j by Molmil](/molmil-images/mine/8e5j) | The crystal structure of 4-n-butylbenzoic acid bound CYP199A4 | Descriptor: | 4-butylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... | Authors: | Doherty, D.Z, Bell, S.G, Bruning, J.B. | Deposit date: | 2022-08-22 | Release date: | 2023-08-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation. Chem Asian J, 17, 2022
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4RM4
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![BU of 4rm4 by Molmil](/molmil-images/mine/4rm4) | The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zhouw, W.H, Zhang, A.L, Zhang, T, Hall, E.A, Hutchinson, S, Cryle, M.J, Wong, L.-L, Bell, S.G. | Deposit date: | 2014-10-18 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.771 Å) | Cite: | The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis. Mol Biosyst, 11, 2015
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5KDY
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8U19
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![BU of 8u19 by Molmil](/molmil-images/mine/8u19) | Crystal structure of SyoA bound to syringol | Descriptor: | 2,6-dimethoxyphenol, Cytochrome P450, MAGNESIUM ION, ... | Authors: | Harlington, A.C, Shearwin, K.E, Bell, S.G, Whelan, F. | Deposit date: | 2023-08-31 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Structural insights into the S-lignin O-demethylase SyoA To Be Published
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8U09
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![BU of 8u09 by Molmil](/molmil-images/mine/8u09) | Crystal structure of substrate-free SyoA | Descriptor: | ACETATE ION, Cytochrome P450, GLYCEROL, ... | Authors: | Harlington, A.H, Shearwin, K.E, Bell, S.G, Whelan, F. | Deposit date: | 2023-08-28 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural insights into the S-lignin O-demethylase SyoA To Be Published
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