3KSC
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![BU of 3ksc by Molmil](/molmil-images/mine/3ksc) | Crystal structure of pea prolegumin, an 11S seed globulin from Pisum sativum L. | Descriptor: | GLYCEROL, LegA class, SULFATE ION | Authors: | Tandang-Silvas, M.R.G, Fukuda, T, Fukuda, C, Prak, K, Cabanos, C, Kimura, A, Itoh, T, Mikami, B, Maruyama, N, Utsumi, S. | Deposit date: | 2009-11-21 | Release date: | 2010-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.606 Å) | Cite: | Conservation and divergence on plant seed 11S globulins based on crystal structures. Biochim.Biophys.Acta, 1804, 2010
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2BPM
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![BU of 2bpm by Molmil](/molmil-images/mine/2bpm) | STRUCTURE OF CDK2-CYCLIN A WITH PHA-630529 | Descriptor: | (2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... | Authors: | Cameron, A, Fogliatto, G, Pevarello, P, Brasca, M.G, Orsini, P, Traquandi, G, Longo, A, Nesi, M, Orzi, F, Piutti, C, Sansonna, P, Varasi, M, Vulpetti, A, Roletto, F, Alzani, R, Ciomei, M, Albanese, C, Pastori, W, Marsiglio, A, Pesenti, E, Fiorentini, F, Bischoff, J.R, Mercurio, C. | Deposit date: | 2005-04-21 | Release date: | 2005-12-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | 3-Aminopyrazole Inhibitors of Cdk2-Cyclin a as Antitumor Agents. 2. Lead Optimization J.Med.Chem., 48, 2005
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2WPA
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![BU of 2wpa by Molmil](/molmil-images/mine/2wpa) | Optimisation of 6,6-Dimethyl Pyrrolo 3,4-c pyrazoles: Identification of PHA-793887, a Potent CDK Inhibitor Suitable for Intravenous Dosing | Descriptor: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, N-{6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1,4,5,6-TETRAHYDROPYRROLO[3,4-C]PYRAZOL-3-YL}-3-METHYLBUTANAMIDE, ... | Authors: | Brasca, M.G, Albanese, C, Alzani, R, Amici, R, Avanzi, N, Ballinari, D, Bischoff, J, Borghi, D, Casale, E, Croci, V, Fiorentini, F, Isacchi, A, Mercurio, C, Nesi, M, Orsini, P, Pastori, W, Pesenti, E, Pevarello, P, Roussel, P, Varasi, M, Volpi, D, Vulpetti, A, Ciomei, M. | Deposit date: | 2009-08-03 | Release date: | 2010-02-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Optimization of 6,6-Dimethyl Pyrrolo[3,4-C]Pyrazoles: Identification of Pha-793887, a Potent Cdk Inhibitor Suitable for Intravenous Dosing. Bioorg.Med.Chem., 18, 2010
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1WA9
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![BU of 1wa9 by Molmil](/molmil-images/mine/1wa9) | Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD | Descriptor: | PERIOD CIRCADIAN PROTEIN | Authors: | Yildiz, O, Doi, M, Yujnovsky, I, Cardone, L, Berndt, A, Hennig, S, Schulze, S, Urbanke, C, Sassone-Corsi, P, Wolf, E. | Deposit date: | 2004-10-25 | Release date: | 2005-01-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal Structure and Interactions of the Pas Repeat Region of the Drosophila Clock Protein Period Mol.Cell, 17, 2005
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4A0G
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![BU of 4a0g by Molmil](/molmil-images/mine/4a0g) | Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana in its apo form. | Descriptor: | ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Cobessi, D, Dumas, R, Pautre, V, Meinguet, C, Ferrer, J.L, Alban, C. | Deposit date: | 2011-09-09 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase-Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis. Plant Cell, 24, 2012
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4A0F
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![BU of 4a0f by Molmil](/molmil-images/mine/4a0f) | Structure of selenomethionine substituted bifunctional DAPA aminotransferase-dethiobiotin synthetase from Arabidopsis thaliana in its apo form. | Descriptor: | ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | Authors: | Cobessi, D, Dumas, R, Pautre, V, Meinguet, C, Ferrer, J.L, Alban, C. | Deposit date: | 2011-09-09 | Release date: | 2012-06-13 | Method: | X-RAY DIFFRACTION (2.714 Å) | Cite: | Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase-Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis. Plant Cell, 24, 2012
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4A0R
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![BU of 4a0r by Molmil](/molmil-images/mine/4a0r) | Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana bound to dethiobiotin (DTB). | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, L(+)-TARTARIC ACID, ... | Authors: | Cobessi, D, Dumas, R, Pautre, V, Meinguet, C, Ferrer, J.L, Alban, C. | Deposit date: | 2011-09-12 | Release date: | 2012-06-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase-Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis. Plant Cell, 24, 2012
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4A0H
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![BU of 4a0h by Molmil](/molmil-images/mine/4a0h) | Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana bound to 7-keto 8-amino pelargonic acid (KAPA) | Descriptor: | 7-KETO-8-AMINOPELARGONIC ACID, ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, L(+)-TARTARIC ACID, ... | Authors: | Cobessi, D, Dumas, R, Pautre, V, Meinguet, C, Ferrer, J.L, Alban, C. | Deposit date: | 2011-09-09 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.808 Å) | Cite: | Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase-Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis. Plant Cell, 24, 2012
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1KNV
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![BU of 1knv by Molmil](/molmil-images/mine/1knv) | Bse634I restriction endonuclease | Descriptor: | ACETATE ION, Bse634I restriction endonuclease, CHLORIDE ION | Authors: | Grazulis, S, Deibert, M, Rimseliene, R, Skirgaila, R, Sasnauskas, G, Lagunavicius, A, Repin, V, Urbanke, C, Huber, R, Siksnys, V. | Deposit date: | 2001-12-19 | Release date: | 2002-02-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence. Nucleic Acids Res., 30, 2002
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1O6T
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![BU of 1o6t by Molmil](/molmil-images/mine/1o6t) | Internalin (INLA, Listeria monocytogenes) - functional domain, uncomplexed | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Schubert, W.-D, Urbanke, C, Ziehm, T, Beier, V, Machner, M.P, Domann, E, Wehland, J, Chakraborty, T, Heinz, D.W. | Deposit date: | 2002-10-15 | Release date: | 2002-12-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of Internalin, a Major Invasion Protein of Listeria Monocytogenes, in Complex with its Human Receptor E-Cadherin Cell(Cambridge,Mass.), 111, 2002
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2Q10
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![BU of 2q10 by Molmil](/molmil-images/mine/2q10) | RESTRICTION ENDONUCLEASE BcnI (WILD TYPE)-COGNATE DNA SUBSTRATE COMPLEX | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3'), ... | Authors: | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, C, Siksnys, V, Bochtler, M. | Deposit date: | 2007-05-23 | Release date: | 2007-06-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Monomeric Restriction Endonuclease BcnI in the Apo Form and in an Asymmetric Complex with Target DNA. J.Mol.Biol., 369, 2007
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1O6S
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![BU of 1o6s by Molmil](/molmil-images/mine/1o6s) | Internalin (Listeria monocytogenes) / E-Cadherin (human) Recognition Complex | Descriptor: | CALCIUM ION, CHLORIDE ION, E-CADHERIN, ... | Authors: | Schubert, W.-D, Urbanke, C, Ziehm, T, Beier, V, Machner, M.P, Domann, E, Wehland, J, Chakraborty, T, Heinz, D.W. | Deposit date: | 2002-10-13 | Release date: | 2002-12-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Internalin, a Major Invasion Protein of Listeria Monocytogenes, in Complex with its Human Receptor E-Cadherin Cell(Cambridge,Mass.), 111, 2002
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1O6V
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![BU of 1o6v by Molmil](/molmil-images/mine/1o6v) | Internalin (INLA, Listeria monocytogenes) - functional domain, uncomplexed | Descriptor: | CALCIUM ION, INTERNALIN A | Authors: | Schubert, W.-D, Urbanke, C, Ziehm, T, Beier, V, Machner, M.P, Domann, E, Wehland, J, Chakraborty, T, Heinz, D.W. | Deposit date: | 2002-10-16 | Release date: | 2002-12-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of Internalin, a Major Invasion Protein of Listeria Monocytogenes, in Complex with its Human Receptor E-Cadherin Cell(Cambridge,Mass.), 111, 2002
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2IHF
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![BU of 2ihf by Molmil](/molmil-images/mine/2ihf) | Crystal structure of deletion mutant delta 228-252 R190A of the single-stranded DNA binding protein from Thermus aquaticus | Descriptor: | Single-stranded DNA-binding protein | Authors: | Fedorov, R, Witte, G, Urbanke, C, Manstein, D.J, Curth, U. | Deposit date: | 2006-09-26 | Release date: | 2007-01-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 3D structure of Thermus aquaticus single-stranded DNA-binding protein gives insight into the functioning of SSB proteins. Nucleic Acids Res., 34, 2006
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2ODI
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![BU of 2odi by Molmil](/molmil-images/mine/2odi) | Restriction Endonuclease BCNI-Cognate DNA Substrate Complex | Descriptor: | 5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3', 5'-D(*CP*TP*CP*CP*GP*GP*GP*TP*TP*GP*T)-3', CALCIUM ION, ... | Authors: | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, C, Siksnys, V, Bochtler, M. | Deposit date: | 2006-12-22 | Release date: | 2007-03-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA. J.Mol.Biol., 369, 2007
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1OSA
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![BU of 1osa by Molmil](/molmil-images/mine/1osa) | |
1B63
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![BU of 1b63 by Molmil](/molmil-images/mine/1b63) | MUTL COMPLEXED WITH ADPNP | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, MUTL, ... | Authors: | Yang, W. | Deposit date: | 1999-01-20 | Release date: | 1999-06-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell(Cambridge,Mass.), 97, 1999
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1B62
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![BU of 1b62 by Molmil](/molmil-images/mine/1b62) | MUTL COMPLEXED WITH ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (MUTL) | Authors: | Wei, Y. | Deposit date: | 1999-01-11 | Release date: | 1999-04-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell(Cambridge,Mass.), 97, 1999
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1AZO
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![BU of 1azo by Molmil](/molmil-images/mine/1azo) | DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI | Descriptor: | 1,2-ETHANEDIOL, MUTH | Authors: | Yang, W. | Deposit date: | 1997-11-19 | Release date: | 1998-05-20 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases. EMBO J., 17, 1998
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2AZO
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![BU of 2azo by Molmil](/molmil-images/mine/2azo) | DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI | Descriptor: | MUTH | Authors: | Yang, W. | Deposit date: | 1997-11-20 | Release date: | 1998-05-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases. EMBO J., 17, 1998
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3SMH
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![BU of 3smh by Molmil](/molmil-images/mine/3smh) | |
2M8E
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![BU of 2m8e by Molmil](/molmil-images/mine/2m8e) | NMR structure of the PAI subdomain of Sleeping Beauty transposase | Descriptor: | SLEEPING BEAUTY TRANSPOSASE | Authors: | Eubanks, C, Schreifels, J, Aronovich, E, Carlson, D, Hacjkett, P, Nesmelova, I. | Deposit date: | 2013-05-17 | Release date: | 2013-12-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structural analysis of Sleeping Beauty transposase binding to DNA. Protein Sci., 23, 2014
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3ENQ
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![BU of 3enq by Molmil](/molmil-images/mine/3enq) | |
3ENW
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![BU of 3enw by Molmil](/molmil-images/mine/3enw) | |
3ENV
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![BU of 3env by Molmil](/molmil-images/mine/3env) | |