1GXH
 
 | | Colicin E8 DNAse immunity protein: Im8 | | Descriptor: | COLICIN E8 IMMUNITY PROTEIN | | Authors: | Leduff, C.S, Videler, H, Boetzel, R, Czisch, M, James, R, Kleanthous, C, Moore, G.R. | | Deposit date: | 2002-04-05 | | Release date: | 2002-05-01 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Non-Cognate Protein-Protein Interaction: The NMR Structure of the Colicin E8 Inhibitor Protein Im8 and its Interaction with the DNase Domain of Colicin E9
To be Published
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1H3L
 | | N-terminal fragment of SigR from Streptomyces coelicolor | | Descriptor: | RNA POLYMERASE SIGMA FACTOR | | Authors: | Li, W, Stevenson, C.E.M, Burton, N, Jakimowicz, P, Paget, M.S.B, Buttner, M.J, Lawson, D.M, Kleanthous, C. | | Deposit date: | 2002-09-10 | | Release date: | 2002-10-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.375 Å) | | Cite: | Identification and Structure of the Anti-Sigma Factor-Binding Domain of the Disulfide-Stress Regulated Sigma Factor Sigma(R) from Streptomyces Coelicolor
J.Mol.Biol., 323, 2002
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5EW5
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5BY4
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7NSU
 | | ColicinE9 intact translocation complex | | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB, ... | | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | | Deposit date: | 2021-03-08 | | Release date: | 2021-08-11 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.
Embo J., 40, 2021
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7NST
 | | ColicinE9 partial translocation complex | | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB | | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | | Deposit date: | 2021-03-08 | | Release date: | 2021-08-11 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.
Embo J., 40, 2021
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1T3O
 | | Solution structure of CsrA, a bacterial carbon storage regulatory protein | | Descriptor: | Carbon storage regulator | | Authors: | Koharudin, L.M.I, Georgiou, T, Kleanthous, C, Geoffrey, R, Kaptein, R, Boelens, R. | | Deposit date: | 2004-04-27 | | Release date: | 2005-10-18 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A model for RNA binding by the bacterial carbon storage regulatory protein, CsrA
To be Published
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2XEV
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2XDJ
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1E44
 | | ribonuclease domain of colicin E3 in complex with its immunity protein | | Descriptor: | 1,2-ETHANEDIOL, COLICIN E3, IMMUNITY PROTEIN | | Authors: | Carr, S, Walker, D, James, R, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2000-06-28 | | Release date: | 2001-06-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Inhibition of a Ribosome Inactivating Ribonuclease: The Crystal Structure of the Cytotoxic Domain of Colicin E3 in Complex with its Immunity Protein
Structure, 8, 2000
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1E0H
 | | Inhibitor Protein Im9 bound to its partner E9 DNase | | Descriptor: | IMMUNITY PROTEIN FOR COLICIN E9 | | Authors: | Boetzel, R, Czisch, M, Kaptein, R, Hemmings, A.M, James, R, Kleanthous, C, Moore, G.R. | | Deposit date: | 2000-03-28 | | Release date: | 2000-10-30 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR investigation of the interaction of the inhibitor protein Im9 with its partner DNase.
Protein Sci., 9, 2000
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1EMV
 | | CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS) | | Descriptor: | COLICIN E9, IMMUNITY PROTEIN IM9, PHOSPHATE ION | | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C. | | Deposit date: | 2000-03-20 | | Release date: | 2000-09-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes.
J.Mol.Biol., 301, 2000
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1AYI
 | | COLICIN E7 IMMUNITY PROTEIN IM7 | | Descriptor: | COLICIN E IMMUNITY PROTEIN 7 | | Authors: | Dennis, C.A, Pauptit, R.A, Wallis, R, James, R, Moore, G.R, Kleanthous, C. | | Deposit date: | 1997-11-04 | | Release date: | 1998-01-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity.
Biochem.J., 333 ( Pt 1), 1998
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2GZJ
 | | Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (D51A) | | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2006-05-11 | | Release date: | 2008-03-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (D51A)
To be Published
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2GZG
 | | Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (Y55F) | | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2006-05-11 | | Release date: | 2008-03-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y55F)
To be Published
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2GZE
 | | Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y55A) | | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2006-05-11 | | Release date: | 2008-03-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y55A)
To be Published
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2GZI
 | | Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A) | | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2006-05-11 | | Release date: | 2008-03-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (V34A)
To be Published
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2GZF
 | | Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F) | | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2006-05-11 | | Release date: | 2007-07-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y54F)
To be Published
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2IVZ
 | | Structure of TolB in complex with a peptide of the colicin E9 T- domain | | Descriptor: | CALCIUM ION, COLICIN-E9, PROTEIN TOLB | | Authors: | Loftus, S.R, Walker, D, Mate, M.J, Bonsor, D.A, James, R, Moore, G.R, Kleanthous, C. | | Deposit date: | 2006-06-23 | | Release date: | 2006-08-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Competitive Recruitment of the Periplasmic Translocation Portal Tolb by a Natively Disordered Domain of Colicin E9
Proc.Natl.Acad.Sci.USA, 103, 2006
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2VLP
 | | R54A mutant of E9 DNase domain in complex with Im9 | | Descriptor: | COLICIN E9, COLICIN-E9 IMMUNITY PROTEIN, MALONIC ACID | | Authors: | Keeble, A.H, Joachimiak, L.A, Mate, M.J, Meenan, N, Kirkpatrick, N, Baker, D, Kleanthous, C. | | Deposit date: | 2008-01-15 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases.
J.Mol.Biol., 379, 2008
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2W8B
 | | Crystal structure of processed TolB in complex with Pal | | Descriptor: | ACETATE ION, GLYCEROL, PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, ... | | Authors: | Sharma, A, Bonsor, D.A, Kleanthous, C. | | Deposit date: | 2009-01-15 | | Release date: | 2009-02-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Allosteric Beta-Propeller Signalling in Tolb and its Manipulation by Translocating Colicins.
Embo J., 28, 2009
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2VLN
 | | N75A mutant of E9 DNase domain in complex with Im9 | | Descriptor: | COLICIN E9, COLICIN-E9 IMMUNITY PROTEIN, MALONIC ACID | | Authors: | Keeble, A.H, Joachimiak, L.A, Mate, M.J, Meenan, N, Kirkpatrick, N, Baker, D, Kleanthous, C. | | Deposit date: | 2008-01-15 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases.
J.Mol.Biol., 379, 2008
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2WQH
 | | Crystal structure of CTPR3Y3 | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | | Authors: | Krachler, A.M, Sharma, A, Kleanthous, C. | | Deposit date: | 2009-08-21 | | Release date: | 2010-04-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Self-association of TPR domains: Lessons learned from a designed, consensus-based TPR oligomer.
Proteins, 78, 2010
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2VLQ
 | | F86A mutant of E9 DNase domain in complex with Im9 | | Descriptor: | COLICIN E9, COLICIN-E9 IMMUNITY PROTEIN, MALONIC ACID | | Authors: | Keeble, A.H, Joachimiak, L.A, Mate, M.J, Meenan, N, Kirkpatrick, N, Baker, D, Kleanthous, C. | | Deposit date: | 2008-01-15 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases.
J.Mol.Biol., 379, 2008
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2VLO
 | | K97A mutant of E9 DNase domain in complex with Im9 | | Descriptor: | COLICIN E9, COLICIN-E9 IMMUNITY PROTEIN, SULFATE ION | | Authors: | Keeble, A.H, Joachimiak, L.A, Mate, M.J, Meenan, N, Kirkpatrick, N, Baker, D, Kleanthous, C. | | Deposit date: | 2008-01-15 | | Release date: | 2008-05-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases.
J.Mol.Biol., 379, 2008
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