2PEE
 
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State | | 分子名称: | GLYCEROL, SULFATE ION, Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-02 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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2PEF
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State | | 分子名称: | Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-03 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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5X5O
 | | Crystal structure of ZAK in complex with compound D2829 | | 分子名称: | Mitogen-activated protein kinase kinase kinase MLT, N-[2,4-bis(fluoranyl)-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-bromanyl-benzenesulfonamide | | 著者 | Dai, Y.B, Zhao, P, Yun, C.H. | | 登録日 | 2017-02-17 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | | 主引用文献 | Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-alpha Motif Kinase (ZAK) Inhibitors.
J. Med. Chem., 60, 2017
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7YAZ
 | | Crystal structure of ZAK in complex with compound YH-186 | | 分子名称: | Mitogen-activated protein kinase kinase kinase MLT, ~{N}-[2,4-bis(fluoranyl)-3-[4-[3-[(3~{S})-1-propanoylpyrrolidin-3-yl]oxy-1~{H}-pyrazolo[3,4-b]pyridin-5-yl]-1,2,3-triazol-1-yl]phenyl]-3-phenyl-benzenesulfonamide | | 著者 | Kong, L.L, Yun, C.H. | | 登録日 | 2022-06-28 | | 公開日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Rational Design of Covalent Kinase Inhibitors by an Integrated Computational Workflow (Kin-Cov).
J.Med.Chem., 66, 2023
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7YAW
 | | Crystal structure of ZAK in complex with compound YH-180 | | 分子名称: | Mitogen-activated protein kinase kinase kinase MLT, ~{N}-[3-[[5-[1-[2,6-bis(fluoranyl)-3-[(3-phenylphenyl)sulfonylamino]phenyl]-1,2,3-triazol-4-yl]-1~{H}-pyrazolo[3,4-b]pyridin-3-yl]oxy]propyl]propanamide | | 著者 | Kong, L.L, Yun, C.H. | | 登録日 | 2022-06-28 | | 公開日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Rational Design of Covalent Kinase Inhibitors by an Integrated Computational Workflow (Kin-Cov).
J.Med.Chem., 66, 2023
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