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5K35
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BU of 5k35 by Molmil
Structure of the Legionella effector, AnkB, in complex with human Skp1
分子名称: Ankyrin-repeat protein B, S-phase kinase-associated protein 1
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2016-05-19
公開日2017-01-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
5K34
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BU of 5k34 by Molmil
Structure of the ankyrin domain of AnkB from Legionella Pneumophila
分子名称: Ankyrin-repeat protein B, GLYCEROL, SULFATE ION
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2016-05-19
公開日2017-01-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
5BU2
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BU of 5bu2 by Molmil
Structure of the C-terminal domain of lpg1496 from Legionella pneumophila in complex with nucleotide
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, alpha-D-ribofuranose, ...
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
5BTW
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BU of 5btw by Molmil
Structure of the N-terminal domain of lpg1496 from Legionella pneumophila
分子名称: Uncharacterized protein
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
5BTX
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BU of 5btx by Molmil
Structure of the N-terminal domain of lpg1496 from Legionella pneumophila in complex with nucleotide
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, lpg1496
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
5BU0
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BU of 5bu0 by Molmil
Structure of the C-terminal domain of lpg1496 from Legionella pneumophila
分子名称: lpg1496
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
5BTZ
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BU of 5btz by Molmil
Structure of the middle domain of lpg1496 from Legionella pneumophila in P212121 space group
分子名称: lpg1496
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
5BU1
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BU of 5bu1 by Molmil
Structure of the truncated C-terminal domain of lpg1496 from Legionella pneumophila
分子名称: LPG1496, MALONATE ION
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
1Z9I
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BU of 1z9i by Molmil
A Structural Model for the Membrane-Bound Form of the Juxtamembrane Domain of the Epidermal Growth Factor Receptor
分子名称: Epidermal growth factor receptor
著者Choowongkomon, K, Carlin, C.R, Sonnichsen, F.D.
登録日2005-04-02
公開日2005-05-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A Structural Model for the Membrane-bound Form of the Juxtamembrane Domain of the Epidermal Growth Factor Receptor
J.Biol.Chem., 280, 2005
5KDG
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BU of 5kdg by Molmil
Crystal Structure of Salmonella Typhimurium Effector GtgE
分子名称: GLYCEROL, Gifsy-2 prophage protein, SULFATE ION
著者Kozlov, G, Xu, C, Wong, K, Gehring, K, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2016-06-08
公開日2016-11-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of the Salmonella Typhimurium Effector GtgE.
PLoS ONE, 11, 2016
6UAN
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BU of 6uan by Molmil
B-Raf:14-3-3 complex
分子名称: 14-3-3 zeta, Serine/threonine-protein kinase B-raf
著者Kondo, Y, Ognjenovic, J, Banerjee, S, Karandur, D, Merk, A, Kulhanek, K, Wong, K, Roose, J.P, Subramaniam, S, Kuriyan, J.
登録日2019-09-11
公開日2019-09-25
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
Science, 366, 2019
3RTP
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BU of 3rtp by Molmil
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
分子名称: Mitogen-activated protein kinase 10, N-[4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide
著者Bowers, S, Truong, A.P, Neitz, R.J, Hom, R.K, Sealy, J.M, Probst, G.D, Quincy, Q, Peterson, B, Chan, W, Galemmo Jr, R.A, Konradi, A.W, Sham, H.L, Pan, H, Lin, M, Yao, N, Artis, D.R, Zhang, H, Chen, L, Dryer, M, Samant, B, Zmolek, W, Wong, K, Lorentzen, C, Goldbach, E, Tonn, G, Quinn, K.P, Sauer, J, Wright, S, Powell, K, Ruslim, L, Ren, Z, Bard, F, Yednock, T.A, Griswold-Prenne, I.
登録日2011-05-03
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration.
Bioorg.Med.Chem.Lett., 21, 2011
5WD8
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BU of 5wd8 by Molmil
Crystal structure of Legionella pneumophila effector lpg2328
分子名称: Lem22
著者Kozlov, G, Wong, K, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2017-07-04
公開日2017-11-29
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.944 Å)
主引用文献Crystal structure of the Legionella effector Lem22.
Proteins, 86, 2018
5VRQ
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BU of 5vrq by Molmil
Crystal structure of Legionella pneumophila effector AnkC
分子名称: Ankyrin repeat-containing protein
著者Kozlov, G, Wong, K, Wang, W, Skubak, P, Munoz-Escobar, J, Liu, Y, Pannu, N.S, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2017-05-11
公開日2017-11-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.205 Å)
主引用文献Ankyrin repeats as a dimerization module.
Biochem. Biophys. Res. Commun., 495, 2018
5WD9
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BU of 5wd9 by Molmil
Crystal structure of Legionella pneumophila effector lpg2328
分子名称: Lem22
著者Kozlov, G, Wong, K, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2017-07-04
公開日2017-11-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the Legionella effector Lem22.
Proteins, 86, 2018
8J7C
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BU of 8j7c by Molmil
Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.88A with an arsenic ion bound at Cys57
分子名称: ARSENIC, Triosephosphate isomerase
著者Kuaprasert, B, Attarataya, J, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Mungthin, M, Leelayoova, S, Choowongkomon, K, Leartsakulpanich, U.
登録日2023-04-27
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
8JBP
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BU of 8jbp by Molmil
Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.45 angstroms resolution with an arsenic atom bound at Cys57
分子名称: ARSENIC, Triosephosphate isomerase
著者Kuaprasert, B, Leartsakulpanich, U, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Robinson, R.C, Zhou, Y, Mungthin, M, Leelayoova, S, Saehlee, S, Choowongkomon, K.
登録日2023-05-09
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
2JS2
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BU of 2js2 by Molmil
Solution structure of first SH3 domain of adaptor Nck
分子名称: Cytoplasmic protein NCK1
著者Hake, M.J, Choowongkomon, K, Carlin, C.R, Sonnichsen, F.D.
登録日2007-06-29
公開日2008-02-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Specificity determinants of a novel Nck interaction with the juxtamembrane domain of the epidermal growth factor receptor.
Biochemistry, 47, 2008
2JS0
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BU of 2js0 by Molmil
Solution structure of second SH3 domain of adaptor Nck
分子名称: Cytoplasmic protein NCK1
著者Hake, M.J, Choowongkomon, K, Carlin, C.R, Sonnichsen, F.D.
登録日2007-06-29
公開日2008-02-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Specificity determinants of a novel Nck interaction with the juxtamembrane domain of the epidermal growth factor receptor.
Biochemistry, 47, 2008
5BTY
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BU of 5bty by Molmil
Structure of the middle domain of lpg1496 from Legionella pneumophila in P21 space group
分子名称: lpg1496
著者Kozlov, G, Zhang, Y, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
2W4P
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BU of 2w4p by Molmil
Human common-type acylphosphatase variant, A99G
分子名称: ACYLPHOSPHATASE-1, GLYCEROL
著者Lam, S.Y, Sze, K.H, Wong, K.B.
登録日2008-11-29
公開日2009-12-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity.
Plos Biol., 9, 2011
2W4D
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BU of 2w4d by Molmil
Acylphosphatase variant G91A from Pyrococcus horikoshii
分子名称: ACYLPHOSPHATASE, PHOSPHATE ION, POTASSIUM ION
著者Lam, S.Y, Wong, K.B.
登録日2008-11-25
公開日2009-12-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity.
Plos Biol., 9, 2011
6P7Z
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BU of 6p7z by Molmil
Co-crystal Structure of human SMYD3 with Isoxazole Amides Inhibitors
分子名称: 5-cyclopropyl-N-[1-(methylsulfonyl)piperidin-4-yl]-1,2-oxazole-3-carboxamide, Histone-lysine N-methyltransferase SMYD3, MAGNESIUM ION, ...
著者Elkins, P.A, Bonnette, W.G.
登録日2019-06-06
公開日2020-01-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors.
Acs Med.Chem.Lett., 11, 2020
6PAF
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BU of 6paf by Molmil
Co-crystal Structure of human SMYD3 with Isoxazole Amides Inhibitors
分子名称: GLYCEROL, Histone-lysine N-methyltransferase SMYD3, MAGNESIUM ION, ...
著者Elkins, P.A, Wang, L.
登録日2019-06-11
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.241 Å)
主引用文献Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors.
Acs Med.Chem.Lett., 11, 2020
2W4C
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BU of 2w4c by Molmil
Human common-type acylphosphatase variant, A99
分子名称: ACYLPHOSPHATASE-1
著者Lam, S.Y, Wong, K.B.
登録日2008-11-25
公開日2009-12-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity.
Plos Biol., 9, 2011

 

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