6FXD
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![BU of 6fxd by Molmil](/molmil-images/mine/6fxd) | Crystal structure of MupZ from Pseudomonas fluorescens | 分子名称: | MupZ | 著者 | Wang, L, Parnell, A, Williams, C, Bakar, N.A, van der Kamp, M.W, Simpson, T.J, Race, P.R, Crump, M.P, Willis, C.L. | 登録日 | 2018-03-08 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis Nat Catal, 2018
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2MVU
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![BU of 2mvu by Molmil](/molmil-images/mine/2mvu) | Solution Structure of the 3,7-dioxo-octyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3,7-dioxooctyl)sulfanyl]ethyl}-beta-alaninamide | 著者 | Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T.J, Willis, C.L, Crump, M.P. | 登録日 | 2014-10-15 | 公開日 | 2015-10-21 | 実験手法 | SOLUTION NMR | 主引用文献 | ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates To be Published
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2MVV
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![BU of 2mvv by Molmil](/molmil-images/mine/2mvv) | Solution Structure of the 5-phenyl-3-oxo-pentyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3-oxo-5-phenylpentyl)sulfanyl]ethyl}-beta-alaninamide | 著者 | Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T.J, Willis, C.L, Crump, M.P. | 登録日 | 2014-10-15 | 公開日 | 2015-10-21 | 実験手法 | SOLUTION NMR | 主引用文献 | ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates To be Published
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7QU9
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![BU of 7qu9 by Molmil](/molmil-images/mine/7qu9) | Structure of aminodeoxychorismate synthase component 1 (PabB) from Bacillus subtilis spizizenii. | 分子名称: | Anthranilate synthase component I family protein, GLYCEROL, TRYPTOPHAN | 著者 | Rooms, L.D, Race, P.R, Back, C.B, Burton, N.B, Willis, C.L, Stach, J.E.M, Duke, P.W, Hawkins, C. | 登録日 | 2022-01-17 | 公開日 | 2023-01-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structure of aminodeoxychorismate synthase component 1 (PabB) from Bacillus subtilis spizizenii. To Be Published
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5E1V
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5DZ6
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![BU of 5dz6 by Molmil](/molmil-images/mine/5dz6) | Acyl transferase from Bacillaene PKS | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... | 著者 | Till, M, Race, P.R. | 登録日 | 2015-09-25 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Architectural hierarchy of trans-acting enoyl reductases from polyunsaturated fatty acid and trans-acyltransferase polyketide synthases To Be Published
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8OF7
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![BU of 8of7 by Molmil](/molmil-images/mine/8of7) | Cyc15 Diels Alderase | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Back, C.R, Barringer, R.W.L, Zorn, K, Manzo-Ruiz, M, Race, P.R. | 登録日 | 2023-03-14 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases. Chembiochem, 24, 2023
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5NO5
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![BU of 5no5 by Molmil](/molmil-images/mine/5no5) | AbyA5 Wildtype | 分子名称: | AbyA5 | 著者 | Byrne, M.J, Race, P.R. | 登録日 | 2017-04-10 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis. Angew.Chem.Int.Ed.Engl., 58, 2019
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6TBB
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6TBC
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![BU of 6tbc by Molmil](/molmil-images/mine/6tbc) | Crystal structure of S. aureus FabI in complex with NADPH and kalimantacin B | 分子名称: | (2~{E},5~{R},10~{E},12~{E},15~{S},19~{R})-20-[[(2~{R},3~{R})-3-aminocarbonyloxy-2-methyl-butanoyl]amino]-3,5,15-trimethyl-7-methylidene-19-oxidanyl-17-oxidanylidene-icosa-2,10,12-trienoic acid, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Fage, C.D, Masschelein, J. | 登録日 | 2019-11-01 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI. Angew.Chem.Int.Ed.Engl., 59, 2020
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6TG5
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7PI1
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![BU of 7pi1 by Molmil](/molmil-images/mine/7pi1) | Bacillus subtilis PabB | 分子名称: | Aminodeoxychorismate synthase component 1, MAGNESIUM ION, TRYPTOPHAN | 著者 | Rooms, L.D, Race, P.R. | 登録日 | 2021-08-19 | 公開日 | 2022-09-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | Crystal structure of Bacillus subtilis PabB, component 1. To be published
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7PXO
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![BU of 7pxo by Molmil](/molmil-images/mine/7pxo) | Structure of the Diels Alderase enzyme AbyU, from Micromonospora maris, co-crystallised with a non transformable substrate analogue | 分子名称: | (2~{S},4~{S})-1-(4-methoxy-5-methyl-2-oxidanylidene-3~{H}-furan-3-yl)-2,4-dimethyl-dodecane-1,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, YD repeat-containing protein | 著者 | Back, C.R, Race, P.R. | 登録日 | 2021-10-08 | 公開日 | 2022-11-16 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Delineation of the Complete Reaction Cycle of a Natural Diels-Alderase To Be Published
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7QAN
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![BU of 7qan by Molmil](/molmil-images/mine/7qan) | Cytochrome P450 Enzyme AbyV | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, Cytochrome P450, ... | 著者 | Parnell, A.E, Back, C.R, Race, P.R. | 登録日 | 2021-11-17 | 公開日 | 2022-11-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis. Angew.Chem.Int.Ed.Engl., 62, 2023
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4YWF
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![BU of 4ywf by Molmil](/molmil-images/mine/4ywf) | AbyA5 | 分子名称: | AbyA5 | 著者 | Byrne, M.J, Race, P.R. | 登録日 | 2015-03-20 | 公開日 | 2016-06-29 | 最終更新日 | 2019-06-19 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis. Angew.Chem.Int.Ed.Engl., 58, 2019
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4Q1H
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![BU of 4q1h by Molmil](/molmil-images/mine/4q1h) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI, ... | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
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4Q1K
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4Q1J
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![BU of 4q1j by Molmil](/molmil-images/mine/4q1j) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 1,2-ETHANEDIOL, Polyketide biosynthesis enoyl-CoA isomerase PksI, SODIUM ION | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
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4Q1I
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4Q1G
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![BU of 4q1g by Molmil](/molmil-images/mine/4q1g) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
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5DYQ
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![BU of 5dyq by Molmil](/molmil-images/mine/5dyq) | AbyU L73M L139M | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, YD repeat-containing protein | 著者 | Byrne, M.J, Race, P.R. | 登録日 | 2015-09-25 | 公開日 | 2016-06-08 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail. J.Am.Chem.Soc., 138, 2016
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5DYV
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![BU of 5dyv by Molmil](/molmil-images/mine/5dyv) | AbyU - wildtype | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, YD repeat-containing protein | 著者 | Race, P.R, Byrne, M.J. | 登録日 | 2015-09-25 | 公開日 | 2016-06-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail. J.Am.Chem.Soc., 138, 2016
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2KGD
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![BU of 2kgd by Molmil](/molmil-images/mine/2kgd) | NMR Solution Structures of 3-oxo-butyl-ACP, an intermediate mimic from the actinorhodin polyketide synthase in Streptomyces coelicolor | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(3-oxobutyl)sulfanyl]ethyl}-beta-alaninamide | 著者 | Crump, M.P, Evans, S.E, Williams, C. | 登録日 | 2009-03-08 | 公開日 | 2009-04-14 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
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2KGC
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2KOO
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