1UWX
 
 | | P1.2 serosubtype antigen derived from N. meningitidis PorA in complex with Fab fragment | | 分子名称: | ANTIBODY, CLASS 1 OUTER MEMBRANE PROTEIN VARIABLE REGION 2, PROTEIN G-PRIME | | 著者 | Tzitzilonis, C, Prince, S.M, Collins, R.F, Maiden, M.C.J, Feavers, I.M, Derrick, J.P. | | 登録日 | 2004-02-12 | | 公開日 | 2005-06-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Variation and Immune Recognition of the P1.2 Subtype Meningococcal Antigen.
Proteins: Struct., Funct., Bioinf., 62, 2005
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5LAO
 | | S-nitrosylated 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | | 登録日 | 2016-06-14 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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5LAM
 | | Refined 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | | 登録日 | 2016-06-14 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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2IVW
 | | The solution structure of a domain from the Neisseria meningitidis PilP pilot protein. | | 分子名称: | PILP PILOT PROTEIN | | 著者 | Golovanov, A.P, Balasingham, S, Tzitzilonis, C, Goult, B.T, Lian, L.-Y, Homberset, H, Tonjum, T, Derrick, J.P. | | 登録日 | 2006-06-20 | | 公開日 | 2007-02-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of a domain from the Neisseria meningitidis lipoprotein PilP reveals a new beta-sandwich fold.
J. Mol. Biol., 364, 2006
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8CVZ
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8CVY
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8CVX
 | | Human glycogenin-1 and glycogen synthase-1 complex in the presence of glucose-6-phosphate | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase, muscle, ... | | 著者 | Liu, Y, Fastman, N.M, Tzitzilonis, C. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex.
Cell Rep, 40, 2022
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2MOI
 | | 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Bordignon, E, Maslennikov, I, Choe, S, Riek, R. | | 登録日 | 2014-04-26 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure and Functional Analysis of the Integral Membrane Protein YgaP from Escherichia coli.
J.Biol.Chem., 289, 2014
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2MOL
 | | 3D NMR structure of the cytoplasmic rhodanese domain of the full-length inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Bordignon, E, Maslennikov, I, Choe, S, Riek, R. | | 登録日 | 2014-04-27 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure and Functional Analysis of the Integral Membrane Protein YgaP from Escherichia coli.
J.Biol.Chem., 289, 2014
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2MPN
 | | 3D NMR structure of the transmembrane domain of the full-length inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Bordignon, E, Maslennikov, I, Choe, S, Riek, R. | | 登録日 | 2014-05-29 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure and Functional Analysis of the Integral Membrane Protein YgaP from Escherichia coli.
J.Biol.Chem., 289, 2014
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5HBO
 | | Native rhodanese domain of YgaP prepared without DDT is both S-nitrosylated and S-sulfhydrated | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Kwiatkowski, W, Maslennikov, I, Choe, S, Lipton, S.A, Riek, R. | | 登録日 | 2016-01-01 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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5HPA
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5HBL
 | | Native rhodanese domain of YgaP prepared with 1mM DDT is S-nitrosylated | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Kwiatkowski, W, Maslennikov, I, Choe, S, Lipton, S.A, Riek, R. | | 登録日 | 2015-12-31 | | 公開日 | 2016-08-10 | | 最終更新日 | 2021-09-08 | | 実験手法 | X-RAY DIFFRACTION (1.617 Å) | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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5HBP
 | | The crystal of rhodanese domain of YgaP treated with SNOC | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Kwiatkowski, W, Maslennikov, I, Choe, S, Lipton, S.A, Riek, R. | | 登録日 | 2016-01-01 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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5HBQ
 | | C63D mutant of the rhodanese domain of YgaP | | 分子名称: | CHLORIDE ION, Inner membrane protein YgaP, SODIUM ION | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Kwiatkowski, W, Maslennikov, I, Choe, S, Lipton, S.A, Riek, R. | | 登録日 | 2016-01-02 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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8ERA
 | | RMC-5552 in complex with mTORC1 and FKBP12 | | 分子名称: | (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5,9,27-trihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, 1-[6-{[(3M)-4-amino-3-(2-amino-1,3-benzoxazol-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-3,4-dihydroisoquinolin-2(1H)-yl]-3-hydroxypropan-1-one, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | 著者 | Tomlinson, A.C.A, Yano, J.K. | | 登録日 | 2022-10-11 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors.
J.Med.Chem., 66, 2023
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8ER6
 | | FKBP12-FRB in Complex with Compound 11 | | 分子名称: | (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5,9,27-trihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, 1,2-ETHANEDIOL, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | 著者 | Tomlinson, A.C.A, Yano, J.K. | | 登録日 | 2022-10-11 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors.
J.Med.Chem., 66, 2023
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8ER7
 | | FKBP12-FRB in Complex with Compound 12 | | 分子名称: | (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-5,10,21-trimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | 著者 | Tomlinson, A.C.A, Yano, J.K. | | 登録日 | 2022-10-11 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors.
J.Med.Chem., 66, 2023
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