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5AX3
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Crystal structure of ERK2 complexed with allosteric and ATP-competitive inhibitors.
分子名称: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Mitogen-activated protein kinase 1, allosteric and ATP-competitive inhibitor
著者Kinoshita, T, Sugiyama, H, Mori, Y, Takahashi, N, Tomonaga, A.
登録日2015-07-14
公開日2016-02-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献Identification of allosteric ERK2 inhibitors through in silico biased screening and competitive binding assay
Bioorg.Med.Chem.Lett., 26, 2016

221051

件を2024-06-12に公開中

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