8BCS
 
 | | X-ray crystal structure of a de novo designed helix-loop-helix homodimer in an anti arrangement, CC-HP1.0 | | 分子名称: | ACETATE ION, CC-HP1.0 | | 著者 | Edgell, C.L, Mylemans, B, Naudin, E.A, Smith, A.J, Savery, N.J, Woolfson, D.N. | | 登録日 | 2022-10-17 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology.
Acs Synth Biol, 12, 2023
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8BCT
 | | X-ray crystal structure of a de novo selected helix-loop-helix heterodimer in a syn arrangement, 26alpha/26beta | | 分子名称: | 26alpha, 26beta, ACETATE ION, ... | | 著者 | Naudin, E.A, Mylemans, B, Smith, A.J, Savery, N.J, Woolfson, D.N. | | 登録日 | 2022-10-17 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology.
Acs Synth Biol, 12, 2023
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4RGQ
 | | Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP | | 分子名称: | 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, Glycerol-1-phosphate dehydrogenase, ... | | 著者 | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | | 登録日 | 2014-09-30 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
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4RGV
 | | Crystal structure of the Methanocaldococcus jannaschii G1PDH | | 分子名称: | Glycerol-1-phosphate dehydrogenase, MAGNESIUM ION, ZINC ION | | 著者 | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | | 登録日 | 2014-09-30 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
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4RFL
 | | Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii | | 分子名称: | 1,2-ETHANEDIOL, Glycerol-1-phosphate dehydrogenase [NAD(P)+], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | | 登録日 | 2014-09-26 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
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6VR7
 | | Structure of a pseudomurein peptide ligase type C from Methanothermus fervidus | | 分子名称: | ACETOACETIC ACID, GLYCEROL, Mur ligase middle domain protein, ... | | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | | 登録日 | 2020-02-06 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry
FEMS Microbes, 2, 2021
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6VR8
 | | Structure of a pseudomurein peptide ligase type E from Methanothermus fervidus | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Mur ligase middle domain protein, ... | | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | | 登録日 | 2020-02-06 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-02-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
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6PNL
 | | Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus | | 分子名称: | 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S. | | 登録日 | 2019-07-02 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus
To Be Published
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6PMH
 | | Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus | | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S. | | 登録日 | 2019-07-01 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus
To Be Published
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2WA5
 | | Crystal structure of human filamin B actin binding domain at 1.9 Angstroms resolution | | 分子名称: | CARBONATE ION, FILAMIN-B, SULFATE ION | | 著者 | Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J. | | 登録日 | 2009-02-03 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains.
J.Mol.Biol., 390, 2009
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2WA7
 | | Structure of the M202V mutant of human filamin b actin binding domain at 1.85 Angstrom resolution | | 分子名称: | CACODYLATE ION, CARBONATE ION, FILAMIN-B | | 著者 | Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J. | | 登録日 | 2009-02-03 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains.
J.Mol.Biol., 390, 2009
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8W33
 | | Structure of McrD (methyl-coenzyme M reductase operon protein D) from Methanomassiliicoccus luminyensis | | 分子名称: | GLYCEROL, McrD (methyl-coenzyme M reductase operon protein D) | | 著者 | Sutherland-Smith, A.J, Carbone, V, Schofield, L.R, Ronimus, R.S. | | 登録日 | 2024-02-21 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The crystal structure of methanogen McrD, a methyl-coenzyme M reductase-associated protein.
Febs Open Bio, 2024
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7UFP
 | | Structure of a pseudomurein peptide ligase type E from Methanothermus fervidus | | 分子名称: | Mur ligase middle domain protein, SULFATE ION, URIDINE-5'-DIPHOSPHATE | | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | | 登録日 | 2022-03-23 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
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7TZI
 | | Structure of a pseudomurein peptide ligase type E from Methanothermobacter thermautotrophicus | | 分子名称: | Mur ligase family protein | | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | | 登録日 | 2022-02-15 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.911 Å) | | 主引用文献 | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
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6P8C
 | | 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus | | 分子名称: | 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase, CHLORIDE ION, GLYCEROL, ... | | 著者 | Carbone, V, Schofield, L.R, Hannus, I, Sutherland-Smith, A.J, Ronimus, R.S. | | 登録日 | 2019-06-06 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | The Crystal Structure of 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus
To Be Published
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6DNT
 | | UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with UDP-N-acetylmuramic acid | | 分子名称: | (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 1,2-ETHANEDIOL, NAD-dependent epimerase/dehydratase, ... | | 著者 | Carbone, V, Schofield, L.R, Sang, C, Sutherland-Smith, A.J, Ronimus, R.S. | | 登録日 | 2018-06-07 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Structural determination of archaeal UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP-N-acetylmuramic acid.
Proteins, 86, 2018
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5CK7
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5CCF
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4FIO
 | | Crystal Structure of Methenyltetrahydromethanopterin Cyclohydrolase from Methanobrevibacter ruminantium | | 分子名称: | ETHYL ACETATE, ISOPROPYL ALCOHOL, Methenyltetrahydromethanopterin cyclohydrolase | | 著者 | Carbone, V, Schofield, L.R, Beattie, A.K, Sutherland-Smith, A.J, Ronimus, R.S. | | 登録日 | 2012-06-10 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | The crystal structure of methenyltetrahydromethanopterin cyclohydrolase from Methanobrevibacter ruminantium.
Proteins, 81, 2013
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4GMH
 | | Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase | | 分子名称: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ACETATE ION | | 著者 | Brown, R.L, Anderson, B.F, Norris, G.E, Tyler, P.C, Evans, G.B, Sutherland-Smith, A.J. | | 登録日 | 2012-08-15 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase
To be Published
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7JT8
 | | Apo structure of a pseudomurein peptide ligase type E from Methanothermus fervidus | | 分子名称: | MAGNESIUM ION, Mur ligase middle domain protein, SULFATE ION | | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | | 登録日 | 2020-08-17 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
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1DXX
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1A9W
 | | HUMAN EMBRYONIC GOWER II CARBONMONOXY HEMOGLOBIN | | 分子名称: | CARBON MONOXIDE, HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), ... | | 著者 | Sutherland-Smith, A.J, Baker, H.M, Hofmann, O.M, Brittain, T, Baker, E.N. | | 登録日 | 1998-04-11 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of gower II (alpha2 epsilon2) haemoglobin at 2.9 A resolution.
J.Mol.Biol., 280, 1998
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3HOR
 | | Structure of the actin-binding domain of human filamin A (reduced) | | 分子名称: | Filamin-A, PHOSPHATE ION | | 著者 | Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J. | | 登録日 | 2009-06-03 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
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3HOC
 | | Structure of the actin-binding domain of human filamin A mutant E254K | | 分子名称: | Filamin-A, PHOSPHATE ION | | 著者 | Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J. | | 登録日 | 2009-06-02 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
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