5YMA
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5UJ0
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7T6D
| CryoEM structure of the YejM/LapB complex | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Inner membrane protein YejM, ... | 著者 | Mi, W, Shu, S. | 登録日 | 2021-12-13 | 公開日 | 2022-08-17 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli. Nat Commun, 13, 2022
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8V24
| LapB cytoplasmic domain in complex with LpxC | 分子名称: | ACETATE ION, Lipopolysaccharide assembly protein B, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | 著者 | Mi, W, Shu, S. | 登録日 | 2023-11-21 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Dual function of LapB (YciM) in regulating Escherichia coli lipopolysaccharide synthesis. Proc.Natl.Acad.Sci.USA, 121, 2024
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6DTT
| Apo T. maritima MalE2 | 分子名称: | maltose-binding protein MalE2 | 著者 | Cuneo, M.J, Shukla, S. | 登録日 | 2018-06-18 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics. Biochemistry, 57, 2018
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6NHZ
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6VDD
| POL domain of Pol1 from M. smegmatis complex with DNA primer-template and dNTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A*(DCT))-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6VDC
| POL domain of Pol1 from M. smegmatis | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6VDE
| Full-length M. smegmatis Pol1 | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.713 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6DTQ
| Maltose bound T. maritima MalE3 | 分子名称: | MAGNESIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE3 | 著者 | Cuneo, M.J, Shukla, S. | 登録日 | 2018-06-18 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics. Biochemistry, 57, 2018
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6DTU
| Maltotetraose bound T. maritima MalE1 | 分子名称: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE1 | 著者 | Cuneo, M.J, Shukla, S. | 登録日 | 2018-06-18 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics. Biochemistry, 57, 2018
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6E3A
| tRNA 2'-phosphotransferase | 分子名称: | COENZYME A, Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2018-07-13 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation. Nat Commun, 10, 2019
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6DTS
| Maltotetraose bound T. maritima MalE2 | 分子名称: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE2 | 著者 | Cuneo, M.J, Shukla, S. | 登録日 | 2018-06-18 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics. Biochemistry, 57, 2018
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6DTR
| Apo T. maritima MalE3 | 分子名称: | SULFATE ION, maltose-binding protein MalE3 | 著者 | Cuneo, M.J, Shukla, S. | 登録日 | 2018-06-18 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics. Biochemistry, 57, 2018
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6EDE
| tRNA 2'-phosphotransferase | 分子名称: | Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2018-08-09 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.553 Å) | 主引用文献 | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation. Nat Commun, 10, 2019
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6C35
| Mycobacterium smegmatis flap endonuclease mutant D148N | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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6C33
| Mycobacterium smegmatis DNA flap endonuclease | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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6C34
| Mycobacterium smegmatis DNA flap endonuclease mutant D125N | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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8DHD
| Neutron crystal structure of maltotetraose bound tmMBP | 分子名称: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE2 | 著者 | Cuneo, M.J, Shukla, S, Myles, D.A. | 登録日 | 2022-06-27 | 公開日 | 2022-10-12 | 最終更新日 | 2023-10-25 | 実験手法 | NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION | 主引用文献 | Mapping periplasmic binding protein oligosaccharide recognition with neutron crystallography. Sci Rep, 12, 2022
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6C36
| Mycobacterium smegmatis flap endonuclease mutant D208N | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION, PHOSPHATE ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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6NHX
| mycobacterial DNA ligase D complexed with ATP and MES | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent DNA ligase | 著者 | Shuman, S, Unciuleac, M, Goldgur, Y. | 登録日 | 2018-12-24 | 公開日 | 2019-02-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates. J. Biol. Chem., 294, 2019
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6TZX
| Crystal Structure of Fungal RNA Kinase | 分子名称: | INOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-13 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.529 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6U03
| Crystal Structure of Fungal RNA Kinase | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-13 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6U00
| Crystal Structure of Fungal RNA Kinase | 分子名称: | PHOSPHATE ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-13 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6TZO
| Crystal Structure of Fungal RNA Kinase | 分子名称: | 2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-12 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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