3D7A
 
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6NEO
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2DPQ
 | | The crystal structures of the calcium-bound con-G and con-T(K7gamma) dimeric peptides demonstrate a novel metal-dependent helix-forming motif | | 分子名称: | CALCIUM ION, CHLORIDE ION, Conantokin-G | | 著者 | Cnudde, S.E, Prorok, M, Dai, Q, Castellino, F.J, Geiger, J.H. | | 登録日 | 2006-05-13 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif
J.Am.Chem.Soc., 129, 2007
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2DOI
 | | The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcus protein PAM | | 分子名称: | Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM | | 著者 | Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H. | | 登録日 | 2006-04-29 | | 公開日 | 2006-12-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
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2DOH
 | | The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound a to a peptide from the group A streptococcal surface protein PAM | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM | | 著者 | Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H. | | 登録日 | 2006-04-29 | | 公開日 | 2006-12-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
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2DPR
 | | The crystal structures of the calcium-bound con-G and con-T(K7Glu) dimeric peptides demonstrate a novel metal-dependent helix-forming motif | | 分子名称: | CALCIUM ION, Conantokin-T | | 著者 | Cnudde, S.E, Prorok, M, Dai, Q, Castellino, F.J, Geiger, J.H. | | 登録日 | 2006-05-13 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif
J.Am.Chem.Soc., 129, 2007
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2KJ4
 | | Solution structure of the complex of VEK-30 and plasminogen kringle 2 | | 分子名称: | VEK-30, plasminogen | | 著者 | Wang, M, Zajicek, J, Prorok, M, Castellin, F.J. | | 登録日 | 2009-05-21 | | 公開日 | 2009-10-20 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the complex of VEK-30 and plasminogen kringle 2.
J.Struct.Biol., 169, 2010
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2GMT
 | | THREE-DIMENSIONAL STRUCTURE OF CHYMOTRYPSIN INACTIVATED WITH (2S) N-ACETYL-L-ALANYL-L-PHENYLALANYL-CHLOROETHYL KETONE: IMPLICATIONS FOR THE MECHANISM OF INACTIVATION OF SERINE PROTEASES BY CHLOROKETONES | | 分子名称: | (2S) N-ACETYL-L-ALANYL-ALPHAL-PHENYLALANYL-CHLOROETHYLKETONE, GAMMA-CHYMOTRYPSIN | | 著者 | Kreutter, K, Steinmetz, A.C.U, Liang, T.-C, Prorok, M, Abeles, R, Ringe, D. | | 登録日 | 1994-09-07 | | 公開日 | 1994-11-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.
Biochemistry, 33, 1994
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6O5L
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6MC8
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7Z0Z
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant | | 分子名称: | AbiK | | 著者 | Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M. | | 登録日 | 2022-02-24 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7R08
 | | Abortive infection DNA polymerase Abi-P2 | | 分子名称: | Reverse transcriptase | | 著者 | Gapinska, M.A, Figiel, M, Czarnocki Cieciura, M, Nowotny, M, Zajko, W. | | 登録日 | 2022-02-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7R06
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis | | 分子名称: | AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3') | | 著者 | Figiel, M, Nowotny, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W. | | 登録日 | 2022-02-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7R07
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis | | 分子名称: | AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), MAGNESIUM ION | | 著者 | Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M. | | 登録日 | 2022-02-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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8Q2Q
 | | Crystal structure of YTHDC1 in complex with Compound 2b (YL_32) | | 分子名称: | 2-chloranyl-~{N},9-dimethyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 | | 著者 | Bedi, R.K, Li, Y, Caflisch, A. | | 登録日 | 2023-08-03 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
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8Q32
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8Q2W
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8Q4U
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8Q38
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8Q4Q
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8Q2T
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8Q33
 | | Crystal structure of YTHDC1 in complex with Compound 15 (ZA_343) | | 分子名称: | SULFATE ION, YTH domain-containing protein 1, ~{N}-[2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]-2,2,2-tris(fluoranyl)ethanamide | | 著者 | Bedi, R.K, Zalesak, F, Caflisch, A. | | 登録日 | 2023-08-03 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
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8Q4R
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8Q4V
 | | Crystal structure of YTHDC1 in complex with Compound 37 (ZA_356) | | 分子名称: | 2-chloranyl-9-[(3-chlorophenyl)methyl]-~{N}-cyclopropyl-7,8-dihydropurin-6-amine, SULFATE ION, YTH domain-containing protein 1 | | 著者 | Bedi, R.K, Zalesak, F, Caflisch, A. | | 登録日 | 2023-08-07 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
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8Q2R
 | | Crystal structure of YTHDC1 in complex with Compound 3 (ZA_431) | | 分子名称: | 5-chloranyl-~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine, SULFATE ION, YTH domain-containing protein 1 | | 著者 | Bedi, R.K, Zalesak, F, Li, Y, Caflisch, A. | | 登録日 | 2023-08-03 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
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