2WKL
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![BU of 2wkl by Molmil](/molmil-images/mine/2wkl) | Velaglucerase alfa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUCOSYLCERAMIDASE, ... | 著者 | Brumshtein, B, Salinas, P, Peterson, B, Chan, V, Silman, I, Sussman, J.L, Savickas, P.J, Robinson, G.S, Futerman, A.H. | 登録日 | 2009-06-15 | 公開日 | 2009-09-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Characterization of Gene-Activated Human Acid-Beta-Glucosidase: Crystal Structure, Glycan Composition and Internalization Into Macrophages. Glycobiology, 20, 2010
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3RTP
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![BU of 3rtp by Molmil](/molmil-images/mine/3rtp) | Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration | 分子名称: | Mitogen-activated protein kinase 10, N-[4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide | 著者 | Bowers, S, Truong, A.P, Neitz, R.J, Hom, R.K, Sealy, J.M, Probst, G.D, Quincy, Q, Peterson, B, Chan, W, Galemmo Jr, R.A, Konradi, A.W, Sham, H.L, Pan, H, Lin, M, Yao, N, Artis, D.R, Zhang, H, Chen, L, Dryer, M, Samant, B, Zmolek, W, Wong, K, Lorentzen, C, Goldbach, E, Tonn, G, Quinn, K.P, Sauer, J, Wright, S, Powell, K, Ruslim, L, Ren, Z, Bard, F, Yednock, T.A, Griswold-Prenne, I. | 登録日 | 2011-05-03 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration. Bioorg.Med.Chem.Lett., 21, 2011
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7SGO
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7SGN
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7SGP
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3PTG
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![BU of 3ptg by Molmil](/molmil-images/mine/3ptg) | Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor | 分子名称: | C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 10, N-[4-methyl-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide | 著者 | Bowers, S, Truong, A.P, Neitz, J, Neitzel, M, Probst, G.D, Hom, R.K, Konradi, A.W, Sham, H.L, Toth, G, Pan, H, Yao, N, Artis, D.R, Brigham, E.F, Quinn, K.P, Sauer, J, Powell, K, Ruslim, L, Bard, F, Yednock, T.A, Griswold-Prenner, I. | 登録日 | 2010-12-02 | 公開日 | 2011-03-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
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2A8Q
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![BU of 2a8q by Molmil](/molmil-images/mine/2a8q) | 2.6 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29 and Manganese in the Presence of 7-methyl-GDP | 分子名称: | MANGANESE (II) ION, PYROPHOSPHATE 2-, U8 snoRNA-binding protein X29 | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | 登録日 | 2005-07-08 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006
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2A8S
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![BU of 2a8s by Molmil](/molmil-images/mine/2a8s) | 2.45 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29, Manganese and GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, U8 snoRNA-binding protein X29 | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | 登録日 | 2005-07-08 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006
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2A8R
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![BU of 2a8r by Molmil](/molmil-images/mine/2a8r) | 2.45 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29 and Manganese in the Presence of 7-methyl-GTP | 分子名称: | MANGANESE (II) ION, PYROPHOSPHATE 2-, U8 snoRNA-binding protein X29 | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | 登録日 | 2005-07-08 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006
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2A8P
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![BU of 2a8p by Molmil](/molmil-images/mine/2a8p) | 2.7 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29 and Manganese | 分子名称: | MANGANESE (II) ION, U8 snoRNA-binding protein X29 | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | 登録日 | 2005-07-08 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006
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2A8T
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![BU of 2a8t by Molmil](/molmil-images/mine/2a8t) | 2.1 Angstrom Crystal Structure of the Complex Between the Nuclear U8 snoRNA Decapping Nudix Hydrolase X29, Manganese and m7G-PPP-A | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE, MANGANESE (II) ION, ... | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | 登録日 | 2005-07-08 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006
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