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1O75
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Tp47, the 47-Kilodalton Lipoprotein of Treponema pallidum
分子名称: 2,3-di-O-sulfo-alpha-D-glucopyranose-(1-6)-2,3-di-O-sulfo-alpha-D-glucopyranose, 47 KDA MEMBRANE ANTIGEN, XENON
著者Deka, R.K, Machius, M, Norgard, M.V, Tomchick, D.R.
登録日2002-10-23
公開日2002-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the 47-kDa lipoprotein of Treponema pallidum reveals a novel penicillin-binding protein.
J. Biol. Chem., 277, 2002
1K0F
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Crystal structure of Zn(II)-free T. pallidum TroA
分子名称: Periplasmic zinc-binding protein troA
著者Lee, Y.H, Dorwart, M.R, Hazlett, K.R, Deka, R.K, Norgard, M.V, Radolf, J.D, Hasemann, C.A.
登録日2001-09-19
公開日2002-04-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of Zn(II)-free Treponema pallidum TroA, a periplasmic metal-binding protein, reveals a closed conformation.
J.Bacteriol., 184, 2002
4U3Q
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Crystal Structure of Recombinant TP0435 from Treponema pallidum
分子名称: 17 kDa lipoprotein
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2014-07-22
公開日2014-10-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insights into the potential function and membrane organization of the TP0435 (Tp17) lipoprotein from Treponema pallidum derived from structural and biophysical analyses.
Protein Sci., 24, 2015
7MGT
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Ftp from Treponema pallidum bound to an ADP-like inhibitor
分子名称: 1,2-ETHANEDIOL, 2-chloroadenosine 5'-(trihydrogen diphosphate), FAD:protein FMN transferase, ...
著者Brautigam, C.A, Deka, R, Norgard, M.V.
登録日2021-04-13
公開日2021-12-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Inhibition of bacterial FMN transferase: A potential avenue for countering antimicrobial resistance.
Protein Sci., 31, 2022
2V84
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Crystal Structure of the Tp0655 (TpPotD) Lipoprotein of Treponema pallidum
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, SPERMIDINE/PUTRESCINE ABC TRANSPORTER, ...
著者Machius, M, Brautigam, C.A, Tomchick, D.R, Ward, P, Otwinowski, Z, Blevine, J.S, Deka, R.K, Norgard, M.V.
登録日2007-08-02
公開日2007-09-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural and Biochemical Basis for Polyamine Binding to the Tp0655 Lipoprotein of Treponema Pallidum: Putative Role for Tp0655 (Tppotd) as a Polyamine Receptor.
J.Mol.Biol., 373, 2007
4N13
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Crystal Structure of PstS (BB_0215) from Borrelia burgdorferi
分子名称: 1,2-ETHANEDIOL, Phosphate ABC transporter, periplasmic phosphate-binding protein, ...
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2013-10-03
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Sequence, biophysical, and structural analyses of the PstS lipoprotein (BB0215) from Borrelia burgdorferi reveal a likely binding component of an ABC-type phosphate transporter.
Protein Sci., 23, 2014
8FIR
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Crystal structure of TpPta, a phosphotransacetylase from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Phosphate acetyltransferase
著者Brautigam, C.A, Norgard, M.V, Deka, R.K.
登録日2022-12-16
公開日2023-05-31
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Biophysical and biochemical studies support TP0094 as a phosphotransacetylase in an acetogenic energy-conservation pathway in Treponema pallidum.
Plos One, 18, 2023
3U65
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The Crystal Structure of Tat-P(T) (Tp0957)
分子名称: 1,2-ETHANEDIOL, THIOCYANATE ION, Tp33 protein
著者Brautigam, C.A, Tomchick, D.R, Deka, R.K, Norgard, M.V.
登録日2011-10-12
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter.
J.Mol.Biol., 416, 2012
3U64
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The Crystal Structure of Tat-T (Tp0956)
分子名称: Protein TP_0956, SULFATE ION
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2011-10-12
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter.
J.Mol.Biol., 416, 2012
1TOA
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PERIPLASMIC ZINC BINDING PROTEIN TROA FROM TREPONEMA PALLIDUM
分子名称: GLYCEROL, PROTEIN (PERIPLASMIC BINDING PROTEIN TROA), ZINC ION
著者Lee, Y.H, Deka, R.K, Norgard, M.V, Radolf, J.D, Hasemann, C.A.
登録日1999-03-03
公開日1999-07-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone.
Nat.Struct.Biol., 6, 1999
5U2P
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The crystal structure of Tp0737 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Norgard, M.V.
登録日2016-11-30
公開日2017-02-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum.
Protein Sci., 26, 2017
5JX2
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Crystal structure of MglB-2 (Tp0684) from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2016-05-12
公開日2016-08-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.0504 Å)
主引用文献The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology.
Plos One, 11, 2016
7JP2
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Crystal structure of TP0037 from Treponema pallidum, a D-lactate dehydrogenase
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, D-lactate dehydrogenase
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2020-08-07
公開日2020-09-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum.
Mbio, 11, 2020
3PJN
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The crystal structure of Tp34 bound to Zn(II) ion at pH 7.5
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, SULFATE ION, ...
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2010-11-10
公開日2011-11-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Characterization of the Tp34 lipoprotein from Treponema pallidum suggests a role in transition metal homeostasis
To be Published
3PJL
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The crystal structure of Tp34 bound to Co (II) ion at pH 7.5
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, COBALT (II) ION, ...
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2010-11-10
公開日2011-11-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Characterization of the Tp34 lipoprotein from Treponema pallidum suggests a role in transition metal homeostasis
To be Published
1XS5
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The Crystal Structure of Lipoprotein Tp32 from Treponema pallidum
分子名称: METHIONINE, Membrane lipoprotein TpN32
著者Deka, R.K, Neil, L, Hagman, K.E, Machius, M, Tomchick, D.R, Brautigam, C.A, Norgard, M.V.
登録日2004-10-18
公開日2004-11-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural evidence that the 32-kilodalton lipoprotein (Tp32) of Treponema pallidum is an L-methionine-binding protein
J.Biol.Chem., 279, 2004
4DI3
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Crystal structure of a 2:1 complex of Treponema pallidum TatP(T) (Tp0957) bound to TatT (Tp0956)
分子名称: TatP(T) (Tp0957), TatT (Tp0956)
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2012-01-30
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural and Thermodynamic Characterization of the Interaction between Two Periplasmic Treponema pallidum Lipoproteins that are Components of a TPR-Protein-Associated TRAP Transporter (TPAT).
J.Mol.Biol., 420, 2012
4DI4
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Crystal structure of a 3:1 complex of Treponema pallidum TatP(T) (Tp0957) bound to TatT (Tp0956)
分子名称: TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, TatP(T) (Tp0957), ...
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2012-01-30
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.714 Å)
主引用文献Structural and Thermodynamic Characterization of the Interaction between Two Periplasmic Treponema pallidum Lipoproteins that are Components of a TPR-Protein-Associated TRAP Transporter (TPAT).
J.Mol.Biol., 420, 2012
6BGD
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BU of 6bgd by Molmil
The crystal structure of the W145A variant of TpMglB-2 (Tp0684) with bound ligand
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glucose/galactose-binding lipoprotein
著者Brautigam, C.A, Norgard, M.V, Deka, R.K.
登録日2017-10-27
公開日2018-01-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystal structures of MglB-2 (TP0684), a topologically variant d-glucose-binding protein from Treponema pallidum, reveal a ligand-induced conformational change.
Protein Sci., 27, 2018
6BGC
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The crystal structure of the W145A variant of TpMglB-2 (Tp0684) with bound glucose
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glucose/galactose-binding lipoprotein, ...
著者Brautigam, C.A, Norgard, M.V, Deka, R.K.
登録日2017-10-27
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.082 Å)
主引用文献Crystal structures of MglB-2 (TP0684), a topologically variant d-glucose-binding protein from Treponema pallidum, reveal a ligand-induced conformational change.
Protein Sci., 27, 2018
6DET
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BU of 6det by Molmil
The crystal structure of Tv2483 bound to L-arginine
分子名称: ARGININE, Tv2483
著者Brautigam, C.A, Norgard, M.V.
登録日2018-05-13
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Biophysical insights into a highly selective l-arginine-binding lipoprotein of a pathogenic treponeme.
Protein Sci., 27, 2018
2FQX
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PnrA from Treponema pallidum complexed with guanosine
分子名称: GUANOSINE, Membrane lipoprotein tmpC
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2006-01-18
公開日2006-02-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
2FQW
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PnrA from Treponema pallidum as purified from E. coli (bound to inosine)
分子名称: INOSINE, Membrane lipoprotein tmpC
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2006-01-18
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
2FQY
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PnrA from Treponema pallidum complexed with adenosine.
分子名称: ADENOSINE, Membrane lipoprotein tmpC
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2006-01-18
公開日2006-02-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
4IFW
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Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, ADP inhibited form
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Thiamine biosynthesis lipoprotein ApbE
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2012-12-15
公開日2013-02-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3001 Å)
主引用文献The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis.
J.Biol.Chem., 288, 2013

 

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