2BVR
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![BU of 2bvr by Molmil](/molmil-images/mine/2bvr) | Human thrombin complexed with fragment-based small molecules occupying the S1 pocket | 分子名称: | 2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE, ALPHA THROMBIN, HIRUDIN VARIANT-2 | 著者 | Neumann, T, Junker, H.-D, Keil, O, Burkert, K, Ottleben, H, Gamer, J, Sekul, R, Deppe, H, Feurer, A, Tomandl, D, Metz, G. | 登録日 | 2005-07-04 | 公開日 | 2006-10-25 | 最終更新日 | 2016-12-21 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Discovery of Thrombin Inhibitor Fragments from Chemical Microarray Screening Lett.Drug Des.Discovery, 2, 2005
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2BVS
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![BU of 2bvs by Molmil](/molmil-images/mine/2bvs) | Human thrombin complexed with fragment-based small molecules occupying the S1 pocket | 分子名称: | ALPHA THROMBIN, HIRUDIN VARIANT-2, N-[2-(2-CARBAMOYLMETHOXY-ETHOXY)-ETHYL]-2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE | 著者 | Neumann, T, Junker, H.-D, Keil, O, Burkert, K, Ottleben, H, Gamer, J, Sekul, R, Deppe, H, Feurer, A, Tomandl, D, Metz, G. | 登録日 | 2005-07-04 | 公開日 | 2006-10-25 | 最終更新日 | 2016-12-21 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Discovery of Thrombin Inhibitor Fragments from Chemical Microarray Screening Lett.Drug Des.Discovery, 2, 2005
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7NHT
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![BU of 7nht by Molmil](/molmil-images/mine/7nht) | Akirin2 bound human proteasome | 分子名称: | Akirin-2, POTASSIUM ION, Proteasome subunit alpha type-1, ... | 著者 | Singh, K, Brunner, H, Grishkovskaya, I, de Almeida, M, Hinterndorfer, M, Zuber, J, Haselbach, D. | 登録日 | 2021-02-11 | 公開日 | 2021-09-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | AKIRIN2 controls the nuclear import of proteasomes in vertebrates. Nature, 599, 2021
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3I7G
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![BU of 3i7g by Molmil](/molmil-images/mine/3i7g) | MMP-13 in complex with a non zinc-chelating inhibitor | 分子名称: | 5-(4-chlorophenyl)-N-[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]furan-2-carboxamide, CALCIUM ION, Collagenase 3, ... | 著者 | Farrow, N.A. | 登録日 | 2009-07-08 | 公開日 | 2009-09-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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3I7I
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![BU of 3i7i by Molmil](/molmil-images/mine/3i7i) | MMP-13 in complex with a non zinc-chelating inhibitor | 分子名称: | CALCIUM ION, Collagenase 3, N-[4-(5-{[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]carbamoyl}furan-2-yl)phenyl]-1-benzofuran-2-carboxamide, ... | 著者 | Farrow, N.A, Margarit, S.M. | 登録日 | 2009-07-08 | 公開日 | 2009-09-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.208 Å) | 主引用文献 | Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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