2XZA
| Crystal Structure of recombinant A.17 antibody FAB fragment | 分子名称: | FAB A.17 HEAVY CHAIN, FAB A.17 LIGHT CHAIN | 著者 | Carletti, E, Nachon, F, Nicolet, Y, Masson, P, Kurkova, I, Smirnov, I, Friboulet, A, Tramontano, A, Gabibov, A. | 登録日 | 2010-11-24 | 公開日 | 2011-09-21 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Reactibodies Generated by Kinetic Selection Couple Chemical Reactivity with Favorable Protein Dynamics. Proc.Natl.Acad.Sci.USA, 108, 2011
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2XZC
| Crystal Structure of phosphonate-modified recombinant A.17 antibody FAB fragment | 分子名称: | 8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-YL PHENYLPHOSPHONATE, CHLORIDE ION, FAB A.17 HEAVY CHAIN, ... | 著者 | Carletti, E, Nachon, F, Nicolet, Y, Masson, P, Kurkova, I, Smirnov, I, Friboulet, A, Tramontano, A, Gabibov, A. | 登録日 | 2010-11-24 | 公開日 | 2011-09-21 | 最終更新日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Reactibodies Generated by Kinetic Selection Couple Chemical Reactivity with Favorable Protein Dynamics. Proc.Natl.Acad.Sci.USA, 108, 2011
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6G5G
| Crystal structure of an engineered Botulinum Neurotoxin type B mutant E1191M/S1199Y in complex with human synaptotagmin 2 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | 著者 | Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P. | 登録日 | 2018-03-29 | 公開日 | 2019-01-16 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models. Sci Adv, 5, 2019
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6G5F
| Crystal structure of an engineered Botulinum Neurotoxin type B mutant E1191M/S1199Y in complex with human synaptotagmin 1 | 分子名称: | Botulinum neurotoxin type B, GLYCEROL, MALONATE ION, ... | 著者 | Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P. | 登録日 | 2018-03-29 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models. Sci Adv, 5, 2019
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6G5K
| Crystal structure of the binding domain of Botulinum Neurotoxin type B in complex with human synaptotagmin 1 | 分子名称: | Botulinum neurotoxin type B, Synaptotagmin-1 | 著者 | Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P. | 登録日 | 2018-03-29 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models. Sci Adv, 5, 2019
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6VBG
| Lactose permease complex with thiodigalactoside and nanobody 9043 | 分子名称: | Galactoside permease, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose, nanobody 9043, ... | 著者 | Kumar, H, Stroud, R.M, Kaback, H.R, Finer-Moore, J, Smirnova, I, Kasho, V, Pardon, E, Steyart, J. | 登録日 | 2019-12-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Diversity in kinetics correlated with structure in nano body-stabilized LacY. Plos One, 15, 2020
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5K59
| Crystal structure of LukGH from Staphylococcus aureus in complex with a neutralising antibody | 分子名称: | CHLORIDE ION, Fab heavy chain, Fab light chain, ... | 著者 | Welin, M, Logan, D.T, Badarau, A, Mirkina, I, Zauner, G, Dolezilkova, I, Nagy, E. | 登録日 | 2016-05-23 | 公開日 | 2016-08-10 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies. Mabs, 8, 2016
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6C9W
| Crystal Structure of a ligand bound LacY/Nanobody Complex | 分子名称: | 4-nitrophenyl alpha-D-galactopyranoside, Lactose permease, Nanobody9047, ... | 著者 | Kumar, H, Finer-Moore, J.S, Jiang, X, Smirnova, I, Kasho, V, Pardon, E, Steyaert, J, Kaback, H.R, Stroud, R.M. | 登録日 | 2018-01-29 | 公開日 | 2018-08-15 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of a ligand-bound LacY-Nanobody Complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1M07
| RESIDUES INVOLVED IN THE CATALYSIS AND BASE SPECIFICITY OF CYTOTOXIC RIBONUCLEASE FROM BULLFROG (RANA CATESBEIANA) | 分子名称: | 5'-D(*AP*CP*GP*A)-3', Ribonuclease | 著者 | Leu, Y.-J, Chern, S.-S, Wang, S.-C, Hsiao, Y.-Y, Amiraslanov, I, Liaw, Y.-C, Liao, Y.-D. | 登録日 | 2002-06-12 | 公開日 | 2003-01-21 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography J.Biol.Chem., 278, 2003
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3OSF
| The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-2f-13 DNA | 分子名称: | 5'-D(*CP*AP*AP*GP*AP*CP*GP*AP*TP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*AP*TP*CP*GP*TP*CP*TP*TP*G)-3', ISOPROPYL ALCOHOL, ... | 著者 | Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H. | 登録日 | 2010-09-09 | 公開日 | 2011-08-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | 主引用文献 | Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 39, 2011
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3OSG
| The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-1-12 DNA | 分子名称: | 5'-D(*AP*AP*AP*TP*AP*TP*CP*GP*TP*TP*AP*T)-3', 5'-D(*AP*TP*AP*AP*CP*GP*AP*TP*AP*TP*TP*T)-3', MYB21 | 著者 | Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H. | 登録日 | 2010-09-09 | 公開日 | 2011-08-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 39, 2011
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1PV6
| Crystal structure of lactose permease | 分子名称: | Lactose permease | 著者 | Abramson, J, Smirnova, I, Kasho, V, Verner, G, Kaback, H.R, Iwata, S. | 登録日 | 2003-06-26 | 公開日 | 2003-08-12 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure and mechanism of the lactose permease of Escherichia coli SCIENCE, 301, 2003
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1PV7
| Crystal structure of lactose permease with TDG | 分子名称: | Lactose permease, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose | 著者 | Abramson, J, Smirnova, I, Kasho, V, Verner, G, Kaback, H.R, Iwata, S. | 登録日 | 2003-06-26 | 公開日 | 2003-08-12 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure and mechanism of the lactose permease of Escherichia coli SCIENCE, 301, 2003
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2QLK
| Adenovirus AD35 fibre head | 分子名称: | Fiber, GLYCEROL | 著者 | Liaw, Y.-C, Amiraslanov, I, Wang, H, Lieber, A. | 登録日 | 2007-07-13 | 公開日 | 2008-02-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Identification of CD46 binding sites within the adenovirus serotype 35 fiber knob J.Virol., 81, 2007
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2UYO
| Crystal structure of ML2640c from Mycobacterium leprae in an hexagonal crystal form | 分子名称: | HYPOTHETICAL PROTEIN ML2640 | 著者 | Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M. | 登録日 | 2007-04-11 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria. Protein Sci., 16, 2007
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2UYE
| Double mutant Y110S,F111V DntR from Burkholderia sp. strain DNT in complex with thiocyanate | 分子名称: | GLYCEROL, REGULATORY PROTEIN, THIOCYANATE ION | 著者 | Lonneborg, R, Smirova, I, Dian, C, leonard, G.A, McSweeney, S, Brzezinski, P. | 登録日 | 2007-04-04 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr. J.Mol.Biol., 372, 2007
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2UYF
| Single mutant F111L DntR from Burkholderia sp. strain DNT in complex with thiocyanate | 分子名称: | ACETATE ION, GLYCEROL, REGULATORY PROTEIN, ... | 著者 | Lonneborg, R, Smirova, I, Dian, C, Leonard, G.A, Mcsweeney, S, Brzezinski, P. | 登録日 | 2007-04-04 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr. J.Mol.Biol., 372, 2007
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2V7S
| Crystal structure of the putative lipoprotein LppA from Mycobacterium tuberculosis | 分子名称: | GLYCEROL, PROBABLE CONSERVED LIPOPROTEIN LPPA | 著者 | Grana, M, Miras, I, Haouz, A, Winter, N, Buschiazzo, A, Bellinzoni, M, Alzari, P.M. | 登録日 | 2007-08-01 | 公開日 | 2008-08-26 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structure of Mycobacterium Tuberculosis Lppa, a Lipoprotein Confined to Pathogenic Mycobacteria. Proteins, 78, 2010
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2WAM
| Crystal structure of Mycobacterium tuberculosis unknown function protein Rv2714 | 分子名称: | CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN, GLYCEROL | 著者 | Bellinzoni, M, Grana, M, Buschiazzo, A, Miras, I, Haouz, A, Alzari, P.M. | 登録日 | 2009-02-09 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Mycobacterium Tuberculosis Rv2714, a Representative of a Duplicated Gene Family in Actinobacteria. Acta Crystallogr.,Sect.F, 65, 2009
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2Y84
| DntR Inducer Binding Domain | 分子名称: | GLYCEROL, LYSR-TYPE REGULATORY PROTEIN | 著者 | Devesse, L, Smirnova, I, Lonneborg, R, Kapp, U, Brzezinski, P, Leonard, G.A, Dian, C. | 登録日 | 2011-02-03 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structures of Dntr Inducer Binding Domains in Complex with Salicylate Offer Insights Into the Activation of Lysr-Type Transcriptional Regulators. Mol.Microbiol., 81, 2011
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2Y7R
| DntR Inducer Binding Domain | 分子名称: | LYSR-TYPE REGULATORY PROTEIN | 著者 | Devesse, L, Smirnova, I, Lonneborg, R, Kapp, U, Brzezinski, P, Leonard, G.A, Dian, C. | 登録日 | 2011-02-01 | 公開日 | 2011-12-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Crystal Structures of Dntr Inducer Binding Domains in Complex with Salicylate Offer Insights Into the Activation of Lysr-Type Transcriptional Regulators. Mol.Microbiol., 81, 2011
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2Y7P
| DntR Inducer Binding Domain in Complex with Salicylate. Trigonal crystal form | 分子名称: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 2-HYDROXYBENZOIC ACID, LYSR-TYPE REGULATORY PROTEIN | 著者 | Devesse, L, Smirnova, I, Lonneborg, R, Kapp, U, Brzezinski, P, Leonard, G.A, Dian, C. | 登録日 | 2011-02-01 | 公開日 | 2011-07-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structures of Dntr Inducer Binding Domains in Complex with Salicylate Offer Insights Into the Activation of Lysr-Type Transcriptional Regulators. Mol.Microbiol., 81, 2011
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2Y7K
| DntR Inducer Binding Domain in Complex with Salicylate. Monoclinic crystal form | 分子名称: | 2-HYDROXYBENZOIC ACID, LYSR-TYPE REGULATORY PROTEIN | 著者 | Devesse, L, Smirnova, I, Lonneborg, R, Kapp, U, Brzezinski, P, Leonard, G.A, Dian, C. | 登録日 | 2011-01-31 | 公開日 | 2011-07-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structures of Dntr Inducer Binding Domains in Complex with Salicylate Offer Insights Into the Activation of Lysr-Type Transcriptional Regulators. Mol.Microbiol., 81, 2011
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2UYQ
| Crystal structure of ML2640c from Mycobacterium leprae in complex with S-adenosylmethionine | 分子名称: | HYPOTHETICAL PROTEIN ML2640, S-ADENOSYLMETHIONINE | 著者 | Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M. | 登録日 | 2007-04-11 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria. Protein Sci., 16, 2007
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2Y7W
| DntR Inducer Binding Domain | 分子名称: | 2-HYDROXYBENZOIC ACID, LYSR-TYPE REGULATORY PROTEIN, TETRAETHYLENE GLYCOL | 著者 | Devesse, L, Smirnova, I, Lonneborg, R, Kapp, U, Brzezinski, P, Leonard, G.A, Dian, C. | 登録日 | 2011-02-02 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Crystal Structures of Dntr Inducer Binding Domains in Complex with Salicylate Offer Insights Into the Activation of Lysr-Type Transcriptional Regulators. Mol.Microbiol., 81, 2011
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