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5VO0
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BU of 5vo0 by Molmil
Structure of a TRAF6-Ubc13~Ub complex
分子名称: POTASSIUM ION, TNF receptor-associated factor 6, Ubiquitin, ...
著者Middleton, A.J, Day, C.L.
登録日2017-05-01
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.
Nat Commun, 8, 2017
5VNZ
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BU of 5vnz by Molmil
Structure of a TRAF6-Ubc13~Ub complex
分子名称: TNF receptor-associated factor 6, Ubiquitin, Ubiquitin-conjugating enzyme E2 N, ...
著者Middleton, A.J, Day, C.L.
登録日2017-05-01
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.
Nat Commun, 8, 2017
8GCB
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BU of 8gcb by Molmil
Structure of RNF125 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF125, Ubiquitin-conjugating enzyme E2 D2, ZINC ION
著者Middleton, A.J, Day, C.L, Fokkens, T.J.
登録日2023-03-01
公開日2023-07-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.
Structure, 31, 2023
8GBQ
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BU of 8gbq by Molmil
Structure of RNF125 in complex with UbcH5b
分子名称: E3 ubiquitin-protein ligase RNF125, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ...
著者Middleton, A.J, Day, C.L, Fokkens, T.J.
登録日2023-02-27
公開日2023-07-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.
Structure, 31, 2023
3ULT
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BU of 3ult by Molmil
Crystal structure of an ice-binding protein from the perennial ryegrass, Lolium perenne
分子名称: 1,2-ETHANEDIOL, ETHANOL, Ice recrystallization inhibition protein-like protein
著者Middleton, A.J, Faucher, F, Campbell, R.L, Davies, P.L.
登録日2011-11-11
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site.
J.Mol.Biol., 416, 2012
5DFL
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BU of 5dfl by Molmil
Crystal structure of Ube2K~Ubiquitin conjugate
分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Middleton, A.J, Day, C.L.
登録日2015-08-27
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K.
Sci Rep, 5, 2015
7MYF
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BU of 7myf by Molmil
Ubiquitin variant UbV.k.1 in complex with Ube2k
分子名称: Ubiquitin, Ubiquitin variant UbV.k.1, Ubiquitin-conjugating enzyme E2 K
著者Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
登録日2021-05-21
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
7MYH
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BU of 7myh by Molmil
Ubiquitin variant UbV.k.2 in complex with Ube2k
分子名称: GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K
著者Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
登録日2021-05-21
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
6W9D
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BU of 6w9d by Molmil
RNF12 RING domain in complex with a Ube2d2~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RLIM, IODIDE ION, Ubiquitin, ...
著者Middleton, A.J, Day, C.L.
登録日2020-03-22
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
6W7Z
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BU of 6w7z by Molmil
RNF12 RING domain in complex with Ube2d2
分子名称: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ...
著者Middleton, A.J, Day, C.L.
登録日2020-03-19
公開日2020-05-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
6W9A
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BU of 6w9a by Molmil
RNF12 RING domain in complex with Ube2e2
分子名称: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 E2, ...
著者Middleton, A.J, Day, C.L.
登録日2020-03-22
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
5ULH
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BU of 5ulh by Molmil
Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, GLYCEROL, THIOCYANATE ION, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
5ULF
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BU of 5ulf by Molmil
Crystal Structure of a UbcH5b~Ub conjugate
分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
5ULK
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BU of 5ulk by Molmil
Crystal Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
7R70
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BU of 7r70 by Molmil
Crystal Structure of the UbArk2C fusion protein
分子名称: GLYCEROL, Ubiquitin,E3 ubiquitin-protein ligase RNF165, ZINC ION
著者Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L.
登録日2021-06-24
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022
7R71
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BU of 7r71 by Molmil
Crystal Structure of the UbArk2C-UbcH5b~Ub complex
分子名称: Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ...
著者Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L.
登録日2021-06-24
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022
6CGA
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BU of 6cga by Molmil
Structure of the PR-DUB complex
分子名称: Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso
著者Foglizzo, M, Middleton, A.J, Day, C.L, Mace, P.D.
登録日2018-02-19
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.
Nat Commun, 9, 2018
5TRB
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BU of 5trb by Molmil
Crystal structure of the RNF20 RING domain
分子名称: E3 ubiquitin-protein ligase BRE1A, ZINC ION
著者Foglizzo, M, Middleton, A.J, Day, C.L.
登録日2016-10-25
公開日2016-11-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B.
J.Mol.Biol., 428, 2016
7L3L
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BU of 7l3l by Molmil
Structure of TRAF5 and TRAF6 RING Hetero dimer
分子名称: TNF receptor-associated factor 5, TNF receptor-associated factor 6, ZINC ION
著者Das, A, Middleton, A.J, Padala, P, Day, C.L.
登録日2020-12-17
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure and ubiquitin binding properties of TRAF RING heterodimers.
J.Mol.Biol., 2021
5NKZ
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BU of 5nkz by Molmil
Crystal structure of H. polymorpha ubiquitin conjugating enzyme Pex4p in complex with soluble domain of Pex22p
分子名称: Peroxin 22, Ubiquitin-conjugating enzyme E2-21 kDa
著者Danda, N, Lunev, S, Ali, A, Groves, M.R, Williams, C.
登録日2017-04-03
公開日2018-01-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
5NL8
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BU of 5nl8 by Molmil
Pex4 of Hansenula Polymorpha
分子名称: Ubiquitin-conjugating enzyme E2-21 kDa
著者Groves, M, Williams, C.
登録日2017-04-04
公開日2018-01-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018

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