3B2R
 
 | | Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil | | 分子名称: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, cGMP-specific 3',5'-cyclic phosphodiesterase | | 著者 | Huanchen, W, Mengchun, Y, Howard, R, Sharron, H.F, Hengming, K. | | 登録日 | 2007-10-19 | | 公開日 | 2008-05-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil.
Mol.Pharmacol., 73, 2008
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