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2L4G
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BU of 2l4g by Molmil
Influenza Haemagglutinin fusion peptide mutant G13A
分子名称: Haemagglutinin
著者Lai, A.L, Tamm, L.K.
登録日2010-10-05
公開日2010-10-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Shallow boomerang-shaped influenza hemagglutinin G13A mutant structure promotes leaky membrane fusion.
J.Biol.Chem., 285, 2010
2JRD
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Influenza Hemagglutinin Fusion Domain Mutant F9A
分子名称: Hemagglutinin
著者Lai, A.L, Tamm, L.K.
登録日2007-06-25
公開日2007-07-10
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Locking the kink in the influenza hemagglutinin fusion domain structure.
J.Biol.Chem., 282, 2007
2DCI
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NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5
分子名称: Hemagglutinin
著者Tamm, L.K, Lai, A.L.
登録日2006-01-07
公開日2006-01-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Fusion peptide of influenza hemagglutinin requires a fixed angle boomerang structure for activity
J.Biol.Chem., 281, 2006
1N03
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Model for Active RecA Filament
分子名称: ADENOSINE-5'-DIPHOSPHATE, RecA protein
著者VanLoock, M.S, Yu, X, Yang, S, Lai, A.L, Low, C, Campbell, M.J, Egelman, E.H.
登録日2002-10-10
公開日2003-02-25
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献ATP-Mediated Conformational Changes in the RecA Filament
Structure, 11, 2003
1XOP
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BU of 1xop by Molmil
NMR structure of G1V mutant of influenza hemagglutinin fusion peptide in DPC micelles at pH 5
分子名称: Hemagglutinin
著者Li, Y, Han, X, Lai, A.L, Bushweller, J.H, Cafiso, D.S, Tamm, L.K.
登録日2004-10-06
公開日2005-09-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion.
J.Virol., 79, 2005
1XOO
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NMR structure of G1S mutant of influenza hemagglutinin fusion peptide in DPC micelles at pH 5
分子名称: Hemagglutinin
著者Li, Y, Han, X, Lai, A.L, Bushweller, J.H, Cafiso, D.S, Tamm, L.K.
登録日2004-10-06
公開日2005-09-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion.
J.Virol., 79, 2005
7OLX
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MerTK kinase domain with type 1.5 inhibitor containing a tri-methyl pyrazole group
分子名称: CHLORIDE ION, Tyrosine-protein kinase Mer, ~{N}-[[3-[4-[(dimethylamino)methyl]phenyl]imidazo[1,2-a]pyridin-6-yl]methyl]-~{N}-methyl-5-[3-methyl-5-(1,3,5-trimethylpyrazol-4-yl)pyridin-2-yl]-1,3,4-oxadiazol-2-amine
著者Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Winter-Holt, J.
登録日2021-05-20
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
J.Med.Chem., 64, 2021
7OLV
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MerTK kinase domain with type 1.5 inhibitor containing a di-methyl, cyano pyrazole group
分子名称: 4-[4-[5-[imidazo[1,2-a]pyridin-6-ylmethyl(methyl)amino]-1,3,4-oxadiazol-2-yl]-3-methyl-phenyl]-2,5-dimethyl-pyrazole-3-carbonitrile, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Winter-Holt, J.
登録日2021-05-20
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
J.Med.Chem., 64, 2021
7OLS
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MerTK kinase domain with type 1.5 inhibitor containing a di-methyl pyrazole group
分子名称: 5-[4-(1,5-dimethylpyrazol-4-yl)-2-methyl-phenyl]-~{N}-(imidazo[1,2-a]pyridin-6-ylmethyl)-~{N}-methyl-1,3,4-oxadiazol-2-amine, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Winter-Holt, J.
登録日2021-05-20
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
J.Med.Chem., 64, 2021

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