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6S3W
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BU of 6s3w by Molmil
Solution NMR Structure of TolAIII Bound to a Peptide Derived from the N-terminus of TolB
分子名称: Cell envelope integrity/translocation protein TolA, TolBp
著者Kleanthous, C, Redfield, C, Rajasekar, K, Holmes, P.
登録日2019-06-26
公開日2020-03-25
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism.
Nat Commun, 11, 2020
5FRF
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BU of 5frf by Molmil
Solution structure of reduced and zinc-bound RsrA
分子名称: ANTI-SIGMA FACTOR RSRA, ZINC ION
著者Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C.
登録日2015-12-17
公開日2016-08-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
6THK
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BU of 6thk by Molmil
Structural mechanism of pyocin S5 import into Pseudomonas aeruginosa
分子名称: GLYCEROL, Pyocin S5, ZINC ION
著者Behrens, H.M, Kleanthous, C, Lowe, E.D.
登録日2019-11-20
公開日2020-03-04
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport.
Mbio, 11, 2020
1T3O
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BU of 1t3o by Molmil
Solution structure of CsrA, a bacterial carbon storage regulatory protein
分子名称: Carbon storage regulator
著者Koharudin, L.M.I, Georgiou, T, Kleanthous, C, Geoffrey, R, Kaptein, R, Boelens, R.
登録日2004-04-27
公開日2005-10-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A model for RNA binding by the bacterial carbon storage regulatory protein, CsrA
To be Published
2W8B
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BU of 2w8b by Molmil
Crystal structure of processed TolB in complex with Pal
分子名称: ACETATE ION, GLYCEROL, PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, ...
著者Sharma, A, Bonsor, D.A, Kleanthous, C.
登録日2009-01-15
公開日2009-02-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Allosteric Beta-Propeller Signalling in Tolb and its Manipulation by Translocating Colicins.
Embo J., 28, 2009
8ODT
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BU of 8odt by Molmil
Structure of TolQR complex from E.coli
分子名称: Tol-Pal system protein TolQ, Tol-Pal system protein TolR
著者Webby, M.N, Kleanthous, C, Press, C.E.
登録日2023-03-09
公開日2023-11-01
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Tunable force transduction through the Escherichia coli cell envelope.
Proc.Natl.Acad.Sci.USA, 120, 2023
4V5K
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BU of 4v5k by Molmil
Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Ng, C.L, Lang, K, Meenan, N.A.G, Sharma, A, Kelley, A.C, Kleanthous, C, Ramakrishnan, V.
登録日2010-05-29
公開日2014-07-09
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3.
Nat.Struct.Mol.Biol., 17, 2010
5FRH
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BU of 5frh by Molmil
Solution structure of oxidised RsrA
分子名称: ANTI-SIGMA FACTOR RSRA
著者Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C.
登録日2015-12-17
公開日2016-08-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
5ODW
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BU of 5odw by Molmil
Structure of the FpvAI-pyocin S2 complex
分子名称: Ferripyoverdine receptor, Pyocin-S2, SULFATE ION
著者White, P, Joshi, A, Kleanthous, C.
登録日2017-07-06
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Exploitation of an iron transporter for bacterial protein antibiotic import.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3O0E
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BU of 3o0e by Molmil
Crystal structure of OmpF in complex with colicin peptide OBS1
分子名称: Colicin-E9, Porin OmpF, octyl beta-D-glucopyranoside
著者Wojdyla, J.A, Housden, N.G, Korczynska, J, Grishkovskaya, I, Kirkpatrick, N, Brzozowski, A.M, Kleanthous, C.
登録日2010-07-19
公開日2010-12-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF.
Proc.Natl.Acad.Sci.USA, 107, 2010
4JML
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BU of 4jml by Molmil
Crystal structure of the TolB(P201C)-ColicinE9 TBE peptide(A33C) complex.
分子名称: CALCIUM ION, Colicin-E9, Protein TolB
著者Wojdyla, J.A, Klein, A, Kleanthous, C.
登録日2013-03-14
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF.
Science, 340, 2013
1V13
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BU of 1v13 by Molmil
CRYSTAL STRUCTURE OF THE MUTANT HIS103ALA OF THE COLICIN E9 DNASE DOMAIN IN COMPLEX WITH ZN+2 (2.0 ANGSTROMS)
分子名称: COLICIN E9, ZINC ION
著者Mate, M.J, Kleanthous, C.
登録日2004-04-06
公開日2004-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases
J.Biol.Chem., 279, 2004
1V15
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BU of 1v15 by Molmil
CRYSTAL STRUCTURE OF THE COLICIN E9, MUTANT HIS103ALA, IN COMPLEX WITH ZN+2 AND DSDNA (RESOLUTION 2.4A)
分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*GP*CP)-3', COLICIN E9, ZINC ION
著者Mate, M.J, Kleanthous, C.
登録日2004-04-06
公開日2004-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases
J.Biol.Chem., 279, 2004
1V14
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BU of 1v14 by Molmil
Crystal Structure of the Colicin E9, mutant His103Ala, in complex with Mg+2 and dsDNA (resolution 2.9A)
分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*GP*CP)-3', COLICIN E9, MAGNESIUM ION
著者Mate, M.J, Kleanthous, C.
登録日2004-04-06
公開日2004-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases
J.Biol.Chem., 279, 2004
4QAY
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BU of 4qay by Molmil
Crystal structure of TamA POTRA domains
分子名称: PHOSPHATE ION, Translocation and assembly module TamA
著者Wojdyla, J.A, Mosbahi, K, Walker, D, Kleanthous, C.
登録日2014-05-06
公開日2015-11-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Recognition of autotransporter passenger domains by the TAM complex
To be Published
3U43
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BU of 3u43 by Molmil
Crystal structure of the colicin E2 DNase-Im2 complex
分子名称: CALCIUM ION, Colicin-E2, Colicin-E2 immunity protein, ...
著者Wojdyla, J.A, Kleanthous, C.
登録日2011-10-07
公開日2012-03-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structure of the Ultra-High-Affinity Colicin E2 DNase-Im2 Complex.
J.Mol.Biol., 417, 2012
4UHP
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BU of 4uhp by Molmil
Crystal structure of the pyocin AP41 DNase-Immunity complex
分子名称: BACTERIOCIN IMMUNITY PROTEIN, LARGE COMPONENT OF PYOCIN AP41
著者Joshi, A, Chen, S, Wojdyla, J.A, Kaminska, R, Kleanthous, C.
登録日2015-03-25
公開日2015-08-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa
J.Mol.Biol., 427, 2015
4UHQ
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BU of 4uhq by Molmil
Crystal structure of the pyocin AP41 DNase
分子名称: CITRIC ACID, LARGE COMPONENT OF PYOCIN AP41, NICKEL (II) ION
著者Joshi, A, Chen, S, Wojdyla, J.A, Kaminska, R, Kleanthous, C.
登録日2015-03-25
公開日2015-08-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa
J.Mol.Biol., 427, 2015
4UDM
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BU of 4udm by Molmil
Crystal structure of Im3 in complex with Y52A mutant of E3RNase
分子名称: CALCIUM ION, CHLORIDE ION, COLICIN-E3, ...
著者Sharma, A, Kleanthous, C.
登録日2014-12-10
公開日2016-01-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Consequences of Inducing Intrinsic Disorder in a High-Affinity Protein-Protein Interaction.
J.Am.Chem.Soc., 137, 2015
1AYI
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BU of 1ayi by Molmil
COLICIN E7 IMMUNITY PROTEIN IM7
分子名称: COLICIN E IMMUNITY PROTEIN 7
著者Dennis, C.A, Pauptit, R.A, Wallis, R, James, R, Moore, G.R, Kleanthous, C.
登録日1997-11-04
公開日1998-01-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity.
Biochem.J., 333 ( Pt 1), 1998
5BY4
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BU of 5by4 by Molmil
Structure and function of the Escherichia coli Tol-Pal stator protein TolR
分子名称: Protein TolR, SODIUM ION
著者Wojdyla, J.A, Kaminska, R, Kleanthous, C.
登録日2015-06-10
公開日2015-09-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structure and Function of the Escherichia coli Tol-Pal Stator Protein TolR.
J.Biol.Chem., 290, 2015
5EW5
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BU of 5ew5 by Molmil
Crystal Structure of Colicin E9 In Complex with Its Immunity Protein Im9
分子名称: Colicin-E9, Colicin-E9 immunity protein
著者Klein, A, Wojdyla, J.A, Kleanthous, C.
登録日2015-11-20
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and biophysical analysis of nuclease protein antibiotics.
Biochem.J., 473, 2016
1E0H
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BU of 1e0h by Molmil
Inhibitor Protein Im9 bound to its partner E9 DNase
分子名称: IMMUNITY PROTEIN FOR COLICIN E9
著者Boetzel, R, Czisch, M, Kaptein, R, Hemmings, A.M, James, R, Kleanthous, C, Moore, G.R.
登録日2000-03-28
公開日2000-10-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR investigation of the interaction of the inhibitor protein Im9 with its partner DNase.
Protein Sci., 9, 2000
1E44
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ribonuclease domain of colicin E3 in complex with its immunity protein
分子名称: 1,2-ETHANEDIOL, COLICIN E3, IMMUNITY PROTEIN
著者Carr, S, Walker, D, James, R, Kleanthous, C, Hemmings, A.M.
登録日2000-06-28
公開日2001-06-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inhibition of a Ribosome Inactivating Ribonuclease: The Crystal Structure of the Cytotoxic Domain of Colicin E3 in Complex with its Immunity Protein
Structure, 8, 2000
1EMV
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CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS)
分子名称: COLICIN E9, IMMUNITY PROTEIN IM9, PHOSPHATE ION
著者Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C.
登録日2000-03-20
公開日2000-09-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes.
J.Mol.Biol., 301, 2000

 

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