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ELIC cocrystallized with isofluorane in a desensitized state
分子名称:	(2R)-2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, 1.7.6 3-bromanylpropan-1-amine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者	Chen, Q, Kinde, M.N, Arjunan, P, Cohen, A, Xu, Y, Tang, P.
登録日	2015-04-09
公開日	2015-09-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (3.3915 Å)
主引用文献	Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC. Sci Rep, 5, 2015

X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a desensitized state
分子名称:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-BROMOETHANOL, 3-AMINOPROPANE, ...
著者	Chen, Q, Kinde, M, Cohen, A, Xu, Y, Tang, P.
登録日	2016-08-10
公開日	2017-06-21
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC. Structure, 25, 2017

X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a resting state
分子名称:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-BROMOETHANOL, Cys-loop ligand-gated ion channel
著者	Chen, Q, Kinde, M, Cohen, A, Xu, Y, Tang, P.
登録日	2016-08-10
公開日	2017-06-21
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3.4 Å)
主引用文献	Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC. Structure, 25, 2017

ELIC bound with the anesthetic isoflurane in the resting state
分子名称:	(2R)-2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Gamma-aminobutyric-acid receptor subunit beta-1
著者	Chen, Q, Kinde, M, Arjunan, P, Cohen, A, Xu, Y, Tang, P.
登録日	2015-04-09
公開日	2015-09-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC. Sci Rep, 5, 2015