6O94
 
 | | Structure of the IRAK4 kinase domain with compound 17 | | 分子名称: | CALCIUM ION, Interleukin-1 receptor-associated kinase 4, N-{5-[4-(hydroxymethyl)piperidin-1-yl]-1-methyl-2-(morpholin-4-yl)-1H-benzimidazol-6-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide | | 著者 | Yu, C, Drobnick, J, Bryan, M.C, Kiefer, J, Lupardus, P.J. | | 登録日 | 2019-03-13 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors.
J.Med.Chem., 62, 2019
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6O9D
 | | Structure of the IRAK4 kinase domain with compound 5 | | 分子名称: | Interleukin-1 receptor-associated kinase 4, N-{7-[4-(aminomethyl)piperidin-1-yl]quinolin-6-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide | | 著者 | Yu, C, Drobnick, J, Bryan, M.C, Kiefer, J, Lupardus, P.J. | | 登録日 | 2019-03-13 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors.
J.Med.Chem., 62, 2019
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6O95
 | | Structure of the IRAK4 kinase domain with compound 41 | | 分子名称: | Interleukin-1 receptor-associated kinase 4, N-[(2R)-2-(hydroxymethyl)-2-methyl-6-(morpholin-4-yl)-2,3-dihydro-1-benzofuran-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, SULFATE ION | | 著者 | Yu, C, Drobnick, J, Bryan, M.C, Kiefer, J, Lupardus, P.J. | | 登録日 | 2019-03-13 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors.
J.Med.Chem., 62, 2019
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5MFC
 | | Designed armadillo repeat protein YIIIM5AII in complex with (KR)4-GFP | | 分子名称: | (KR)4-Green fluorescent protein,Green fluorescent protein, ACETATE ION, YIIIM5AII | | 著者 | Hansen, S, Kiefer, J, Madhurantakam, C, Mittl, P, Plueckthun, A. | | 登録日 | 2016-11-18 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of designed armadillo repeat proteins binding to peptides fused to globular domains.
Protein Sci., 26, 2017
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5MFD
 | | Designed armadillo repeat protein YIIIM''6AII in complex with pD_(KR)5 | | 分子名称: | CALCIUM ION, Capsid decoration protein,pD_(KR)5, YIIIM''6AII | | 著者 | Hansen, S, Kiefer, J, Madhurantakam, C, Mittl, P, Plueckthun, A. | | 登録日 | 2016-11-18 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of designed armadillo repeat proteins binding to peptides fused to globular domains.
Protein Sci., 26, 2017
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7TBA
 | | Pentraxin - ligand complex | | 分子名称: | C-reactive protein, CALCIUM ION, [3-(dibutylamino)propyl]phosphonic acid | | 著者 | Shing, K.S.C.T, Morton, C.J, Parker, M.W. | | 登録日 | 2021-12-21 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein.
Embo Mol Med, 15, 2023
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