1HNG
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![BU of 1hng by Molmil](/molmil-images/mine/1hng) | CRYSTAL STRUCTURE AT 2.8 ANGSTROMS RESOLUTION OF A SOLUBLE FORM OF THE CELL ADHESION MOLECULE CD2 | 分子名称: | CD2 | 著者 | Jones, E.Y, Davis, S.J, Williams, A.F, Harlos, K, Stuart, D.I. | 登録日 | 1994-08-10 | 公開日 | 1995-02-07 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2. Nature, 360, 1992
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1VCA
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![BU of 1vca by Molmil](/molmil-images/mine/1vca) | CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENT OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ANGSTROMS RESOLUTION | 分子名称: | HUMAN VASCULAR CELL ADHESION MOLECULE-1 | 著者 | Jones, E.Y, Harlos, K, Bottomley, M.J, Robinson, R.C, Driscoll, P.C, Edwards, R.M, Clements, J.M, Dudgeon, T.J, Stuart, D.I. | 登録日 | 1995-03-21 | 公開日 | 1995-09-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution. Nature, 373, 1995
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7B50
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![BU of 7b50 by Molmil](/molmil-images/mine/7b50) | Notum complex with ARUK3003778 | 分子名称: | 3-(3,4-dichlorophenyl)sulfanyl-1$l^{4},2,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4,7-tetraen-9-one, DIMETHYL SULFOXIDE, Palmitoleoyl-protein carboxylesterase NOTUM, ... | 著者 | Jones, E.Y, Fish, P. | 登録日 | 2020-12-03 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity. J.Med.Chem., 65, 2022
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7B4X
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![BU of 7b4x by Molmil](/molmil-images/mine/7b4x) | Notum complex with ARUK3002697 | 分子名称: | 1,2-ETHANEDIOL, 6-(4-methylphenyl)sulfanyl-2~{H}-[1,2,4]triazolo[4,3-b]pyridazin-3-one, DIMETHYL SULFOXIDE, ... | 著者 | Jones, E.Y, Fish, P. | 登録日 | 2020-12-02 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8U
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![BU of 7b8u by Molmil](/molmil-images/mine/7b8u) | Notum-Fragment 201 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(piperidin-1-yl)-1,2,5-oxadiazol-3-amine, Palmitoleoyl-protein carboxylesterase NOTUM, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8M
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![BU of 7b8m by Molmil](/molmil-images/mine/7b8m) | Notum-Fragment 193 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-methoxy-2-(1~{H}-pyrazol-3-yl)phenol, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8O
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![BU of 7b8o by Molmil](/molmil-images/mine/7b8o) | Notum-Fragment 199 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Palmitoleoyl-protein carboxylesterase NOTUM, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8N
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![BU of 7b8n by Molmil](/molmil-images/mine/7b8n) | Notum-Fragment 197 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-azanyl-2-(pyridin-3-ylmethylamino)benzoic acid, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8K
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![BU of 7b8k by Molmil](/molmil-images/mine/7b8k) | Notum-Fragment 173 | 分子名称: | 1,2-ETHANEDIOL, 1~{H}-benzimidazol-2-ylcyanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8J
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![BU of 7b8j by Molmil](/molmil-images/mine/7b8j) | Notum-Fragment 163 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8Z
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![BU of 7b8z by Molmil](/molmil-images/mine/7b8z) | Notum-Fragment 277 | 分子名称: | 2-[4-(3-chlorophenyl)piperazin-1-ium-1-yl]ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8X
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![BU of 7b8x by Molmil](/molmil-images/mine/7b8x) | Notum-Fragment 210 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Palmitoleoyl-protein carboxylesterase NOTUM, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8L
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![BU of 7b8l by Molmil](/molmil-images/mine/7b8l) | Notum-Fragment 174 | 分子名称: | 1,2-ETHANEDIOL, 2,4-bis(fluoranyl)-6-(1~{H}-pyrazol-3-yl)phenol, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8Y
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![BU of 7b8y by Molmil](/molmil-images/mine/7b8y) | Notum-Fragment 276 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(3-ethoxyphenyl)-1,3,4-thiadiazol-2-amine, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-13 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7BLS
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![BU of 7bls by Molmil](/molmil-images/mine/7bls) | Notum-maybridge_18 | 分子名称: | 2-[(3-Nitro-2-pyridyl)thio]acetic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2021-01-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Notum Fragment Screen To Be Published
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7BLI
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![BU of 7bli by Molmil](/molmil-images/mine/7bli) | Notum-Bepridil complex | 分子名称: | 1-ISOBUTOXY-2-PYRROLIDINO-3[N-BENZYLANILINO] PROPANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2021-01-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Notum Fragment Screen To Be Published
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7B8C
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![BU of 7b8c by Molmil](/molmil-images/mine/7b8c) | Notum-Fragment 147 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methyl-~{N}-(2-methylpropyl)imidazo[1,2-a]pyridine-3-carboxamide, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B84
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![BU of 7b84 by Molmil](/molmil-images/mine/7b84) | Notum-Fragment065 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B87
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![BU of 7b87 by Molmil](/molmil-images/mine/7b87) | Notum-Fragment074 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B86
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![BU of 7b86 by Molmil](/molmil-images/mine/7b86) | Notum-Fragment067 | 分子名称: | 1,2-ETHANEDIOL, 2-[4-(1~{H}-pyrazol-3-yl)phenoxy]pyrimidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8D
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![BU of 7b8d by Molmil](/molmil-images/mine/7b8d) | Notum-Fragment 151 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-amino-N-(pyridin-2-yl)benzenesulfonamide, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B8A
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![BU of 7b8a by Molmil](/molmil-images/mine/7b8a) | Notum-Fragment 110 | 分子名称: | 1,2-ETHANEDIOL, 1-cyclohexyl-3-(2-pyridin-4-ylethyl)urea, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Notum Fragment Screen To Be Published
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7B89
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![BU of 7b89 by Molmil](/molmil-images/mine/7b89) | Notum-Fragment077 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Palmitoleoyl-protein carboxylesterase NOTUM, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-12 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
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7B7Y
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![BU of 7b7y by Molmil](/molmil-images/mine/7b7y) | Notum-Fragment064 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-(4-methyl-1,3-thiazol-2-yl)propanamide, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-11 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Notum Fragment Screen To Be Published
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7B7X
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![BU of 7b7x by Molmil](/molmil-images/mine/7b7x) | Notum-Fragment063 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-(2,1,3-benzoxadiazol-4-yl)acetamide, ... | 著者 | Zhao, Y, Jonees, E.Y. | 登録日 | 2020-12-11 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Notum Fragment Screen To Be Published
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