2ANO
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![BU of 2ano by Molmil](/molmil-images/mine/2ano) | Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17 | 分子名称: | 1-{[N-(1-IMINO-GUANIDINO-METHYL)]SULFANYLMETHYL}-3-TRIFLUOROMETHYL-BENZENE, Dihydrofolate reductase, MANGANESE (II) ION, ... | 著者 | Summerfield, R.L, Daigle, D.M, Mayer, S, Jackson, S.G, Organ, M, Hughes, D.W, Brown, E.D, Junop, M.S. | 登録日 | 2005-08-11 | 公開日 | 2006-07-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | A 2.13 A Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region J.Med.Chem., 49, 2006
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2ANQ
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![BU of 2anq by Molmil](/molmil-images/mine/2anq) | Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a. | 分子名称: | (2,5-dimethylbenzene-1,4-diyl)dimethanediyl bis(N-carbamimidoylcarbamimidothioate), Dihydrofolate reductase, MANGANESE (II) ION, ... | 著者 | Summerfield, R.L, Daigle, D.M, Mayer, S, Jackson, S.G, Organ, M, Hughes, D.W, Brown, E.D, Junop, M.S. | 登録日 | 2005-08-11 | 公開日 | 2006-07-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | A 2.13 A Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region J.Med.Chem., 49, 2006
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1Q7G
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![BU of 1q7g by Molmil](/molmil-images/mine/1q7g) | Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline | 分子名称: | Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE-5-HYDROXY-4-OXONORVALINE, SODIUM ION | 著者 | Jacques, S.L, Mirza, I.A, Ejim, L, Koteva, K, Hughes, D.W, Green, K, Kinach, R, Honek, J.F, Lai, H.K, Berghuis, A.M, Wright, G.D. | 登録日 | 2003-08-18 | 公開日 | 2003-10-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Enzyme assisted suicide: Molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase Chem.Biol., 10, 2003
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2HW2
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![BU of 2hw2 by Molmil](/molmil-images/mine/2hw2) | |
3JZ0
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![BU of 3jz0 by Molmil](/molmil-images/mine/3jz0) | LinB complexed with clindamycin and AMPCPP | 分子名称: | CLINDAMYCIN, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Lincosamide nucleotidyltransferase, ... | 著者 | Morar, M, Wright, G.D. | 登録日 | 2009-09-22 | 公開日 | 2009-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB. Structure, 17, 2009
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3JYY
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![BU of 3jyy by Molmil](/molmil-images/mine/3jyy) | SeMet LinB complexed with PPi | 分子名称: | Lincosamide nucleotidyltransferase, MAGNESIUM ION, PYROPHOSPHATE | 著者 | Morar, M, Wright, G.D. | 登録日 | 2009-09-22 | 公開日 | 2009-11-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB. Structure, 17, 2009
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