4GH8
| Crystal structure of a 'humanized' E. coli dihydrofolate reductase | 分子名称: | CALCIUM ION, Dihydrofolate reductase, METHOTREXATE, ... | 著者 | French, J.B, Liu, C.T, Hanoian, P, Pringle, T.H, Hammes-Schiffer, S, Benkovic, S.J. | 登録日 | 2012-08-07 | 公開日 | 2013-06-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans. Proc.Natl.Acad.Sci.USA, 110, 2013
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4P66
| Electrostatics of Active Site Microenvironments of E. coli DHFR | 分子名称: | CALCIUM ION, Dihydrofolate reductase, METHOTREXATE, ... | 著者 | Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J. | 登録日 | 2014-03-21 | 公開日 | 2014-07-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase. J.Am.Chem.Soc., 136, 2014
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4P68
| Electrostatics of Active Site Microenvironments for E. coli DHFR | 分子名称: | ACETATE ION, CALCIUM ION, Dihydrofolate reductase, ... | 著者 | Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J. | 登録日 | 2014-03-22 | 公開日 | 2014-07-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase. J.Am.Chem.Soc., 136, 2014
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